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Andrew J. Dannenberg, M.D., honored with AACR-Prevent Cancer Foundation Award
Date:10/19/2011

rate-limiting enzyme responsible for estrogen synthesis. This latter work led to an observational study in which the use of aspirin was associated with a reduced risk for hormone receptor-positive breast cancer.

In his most recent work that provides new insights into the link between obesity, inflammation and breast cancer, Dannenberg conducted a preclinical study in which he used experimental models to demonstrate the presence of the obesityinflammationaromatase axis in the mammary gland. As a result, COX-2-derived PGE2 appeared to play an important role in inducing aromatase in the mammary glands of obese mice. Subsequently, he successfully translated these preclinical findings.

Dannenberg will present his lecture, "Obesity and Breast Inflammation: Implications for Cancer Prevention," on Sunday, Oct. 23, 2011, at 5:15 p.m.


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Contact: Michele Sharp
Michele.Sharp@aacr.org
267-446-7156
American Association for Cancer Research
Source:Eurekalert

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