Navigation Links
Analysis of Millions of U.S. Births Shows Association Between Birth Defects and Preterm Birth
Date:5/20/2008

WHITE PLAINS, N.Y., May 21 /PRNewswire-USNewswire/ -- Babies born preterm were more than twice as likely to have major birth defects as full-term infants, according to a new analysis of nearly 7 million U.S. live births published online this week in the Springer journal Maternal and Child Health Journal.

Preterm birth, live birth before 37 completed weeks gestation, is a growing national health crisis, according to the March of Dimes. More than a half million babies are born too soon each year, and the rate continues to rise. Birth defects and preterm birth are the leading causes of infant death.

About 8 percent of babies born preterm had a birth defect, according to the research by a team of investigators from the March of Dimes, the U.S. Centers for Disease Control and Prevention (CDC), and several other major institutions.

For this study, the researchers looked at live births between 1995 and 2000 from 13 states, representing about 30 percent of all U.S. births. The findings supported those of earlier, smaller studies.

"The causes of most birth defects are still not known," says Margaret Honein, Ph.D., MPH of the CDC's National Center on Birth Defects and Developmental Disabilities and lead author of the study. "While it is likely that the most common defects are caused by a combination of genetic and environmental factors, the identification of specific risk factors continues to be a major research and public health priority."

Research into the link between birth defects and preterm birth was called for in the PREEMIE Act (P.L. 109-450) that was signed into law in December 2006. The act, which authorized increased federal support for research and education on prematurity, also called for a Surgeon General's Conference, scheduled for June 2008, to establish a public-private agenda on premature birth.

"Infants born preterm were more than twice as likely to have major birth defects as infants born at term, and the association was strongest among very preterm babies," said Joann Petrini, Ph.D., MPH, director of the March of Dimes Perinatal Data Center, who also co-authored the study. "This study highlights the importance of understanding the possible shared causes and risk factors that lead to preterm birth among those infants affected by major birth defects."

Very preterm babies, those born between 24 and 31 weeks gestation, were five times as likely as full-term infants to have a birth defect. The most common birth defects for this group were central nervous system defects, such as spina bifida, and cardiovascular defects, such as a hole in the heart.

"The Association Between Major Birth Defects and Preterm Birth" by Honein, et al. was published online this week at:

http://dx.doi.org/10.1007/s10995-008-0348-y. The article is available free of charge.

Springer Science+Business Media (http://www.springer.com) is one of the world's leading suppliers of scientific and specialist literature. It is the second-largest publisher of journals in the science, technology, and medicine (STM) sector and the largest publisher of STM books. The group publishes more than 1,700 journals and more than 5,500 new books a year, as well as the largest STM eBook Collection worldwide.

The March of Dimes is the leading nonprofit organization for pregnancy and baby health. With chapters nationwide and its premier event, March for Babies(SM), the March of Dimes works to improve the health of babies by preventing birth defects, premature birth and infant mortality. For the latest resources and information, visit marchofdimes.com or nacersano.org. And for detailed national, state and local perinatal statistics, visit PeriStats at http://www.marchofdimes.com/peristats.


'/>"/>
SOURCE March of Dimes
Copyright©2008 PR Newswire.
All rights reserved

Related medicine news :

1. Data re-analysis shows drug finasteride reduces risk for most prostate cancers
2. Carnegie Mellon engineering researchers automate analysis of protein patterns
3. Queen Rania Launches Situation Analysis of Children in Jordan Highlighting Jordans Progress in Improving Quality of Life; 6 Ministers Commit to Further Improving Results
4. New analysis shows DAYTRANA offered ADHD symptom control for 12 months
5. PA Governor Says Financial Analysis Shows Nothing Stands in Way of Senate Action to Help Pennsylvanias Uninsured
6. Analysis of alcoholics brains suggests treatment target
7. New Lewin Group Analysis: Medicare Cuts for Nursing Facility Care Could Have Economic Impact Up to $4.2 Billion, Threaten Jobs
8. Carnegie Mellon technique accelerates biological image analysis
9. New analysis finds daycare attendance early in life cuts childhood leukemia risk by 30 percent
10. Analysis shows combining sorafenib with carboplatin/paclitaxel adds no benefit in lung cancer
11. Invention gives improved gene technology analysis
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:2/5/2016)... ... February 05, 2016 , ... Looking for a last-minute Valentine’s Day ... tips of your toes. Foot massage, whether administered by a professional masseuse or a ... The American Board of Multiple Specialties in Podiatry (ABMSP) has taken the ...
(Date:2/5/2016)... ... February 05, 2016 , ... ... from across the country gathered at the La Valencia Hotel in San Diego, ... PROSHRED Chicago was named the year’s most outstanding franchise, walking away with the ...
(Date:2/5/2016)... ... February 05, 2016 , ... Pivot ... 2015 Best in KLAS: Software & Services for HIT Implementation Support & Staffing ... report independently ranks vendor performance by healthcare executives, managers and clinicians representing over ...
(Date:2/5/2016)... ... February 05, 2016 , ... Colorize is a ... drop zone to the next using Colorize's dynamic moving camera. Colorize is perfect for ... includes a 3D slideshow environment with 1 to 5 focus points per scene, stage ...
(Date:2/5/2016)... ... , ... Calls Blacklist has just been updated by mobile app developer Vlad ... has fixed known bugs within the app. Calls Blacklist allows its users to only ... any of their device’s battery power or memory. It provides a powerful call blocker ...
Breaking Medicine News(10 mins):
(Date:2/5/2016)... WARSAW, Ind. , Feb. 5, 2016  Zimmer ... the pricing of the previously announced underwritten secondary offering ... of its stockholders, consisting of affiliates of Blackstone and ... public at an initial price of $96.45 per share. ... of the offering.  Neither Zimmer Biomet nor any of ...
(Date:2/5/2016)... France , Germany , Italy ... ). It includes a 10-year epidemiology forecast for the total prevalent ... sex in these markets. GD epidemiology report is written and developed by ... and market-driven, providing expert analysis of disease trends in the 7MM. ... Italy , Spain , UK, and ...
(Date:2/4/2016)... Feb. 4, 2016  The Senior Care Pharmacy ... Reform Committee Chairman Jason Chaffetz (R-UT) ... today,s hearing , "Developments in the Prescription ... and growing questions about abusive pharmacy benefit manager ... (R-UT) and Ranking Member Elijah Cummings (D-MD) are ...
Breaking Medicine Technology: