Navigation Links
Analysis of Four Large Post-Marketing Surveillance Studies Describe Clinical Effects of Sucrose-Formulated Recombinant Factor VIII
Date:7/13/2009

BOSTON, July 13 /PRNewswire/ -- New data pooled from four large, "real world" post-marketing surveillance studies showed that sucrose-formulated recombinant factor VIII (rFVIII-FS) reduced bleeding and provided data regarding adverse events in more than 950 patients with mild-to-severe hemophilia A. Additionally, rates of inhibitor formation were reported in both previously treated and previously untreated patients. The data were presented at the XXII Congress of the International Society on Thrombosis and Haemostasis (ISTH).(1)(2)

In this analysis, the investigators judged rFVIII-FS hemostasis to be "good" or "very good" in 98.9 percent of patients. Serious adverse drug reactions were seen in 1.1 percent of patients and new (de novo) inhibitors were observed in 0.8 percent of patients.

"In a 'real world' setting, these data reflect some of the extensive global clinical experience with rFVIII-FS," said Georg Lemm, M.D., Ph.D., vice president, Global Clinical Development, and head, Hematology Group, Bayer Schering Pharma. "It is particularly noteworthy that a low rate of inhibitor formation was observed in this analysis of data pooled from post-marketing surveillance studies. Inhibitor formation is a significant challenge for both clinicians and their patients, and its treatment is costly and requires significant time to overcome."

Open label study investigating the efficacy of prophylactic versus on-demand rFVIII-FS treatment

In another presentation, (3) data from an open label clinical study that enrolled 20 adult men with severe hemophilia A (with and without target joints) demonstrated that patients who were changed from on-demand to prophylactic (preventive) infusions of rFVIII-FS had significantly reduced median joint bleeds per 6-month treatment period (zero events versus 15.0 events, respectively; P<0.001) and improved median total Gilbert Scores (18 versus 25, respec
'/>"/>

SOURCE Bayer HealthCare
Copyright©2009 PR Newswire.
All rights reserved

Page: 1 2 3 4 5

Related medicine news :

1. Study, meta-analysis examine factors associated with death from heatstroke
2. Latest DES Analysis Stresses Importance of Physicians Well-Trained in Implantation Technique and Patient Follow-Up
3. Consumer Reports Analysis: Drugs for Nerve Pain, Fibromyalgia Effective, But Not Always Best
4. Takeda statement on ACTOS meta-analysis published in the Journal of the American Medical Association
5. Takeda Statement on ACTOS(R) (Pioglitazone HCl) Meta-Analysis Published in the Journal of the American Medical Association
6. Physical Therapist Provides Injury Analysis for Fantasy Football
7. Sanofi-Aventis renews licenses for Genomatix chip analysis pipeline
8. Meta-Analysis of Blood Phe Levels and Clinical Outcomes in PKU Published
9. OCS and Press Ganey Partner to Create Joint Analysis of Outcomes and Satisfaction
10. New Analysis Underscores Legality of Physician Ranking and Public Reporting Systems When Used by Health Insurers to Improve Health Care Quality
11. Barta joins Conseco as Senior Vice President, Financial Planning & Analysis; Barra named Senior Vice President, Internal Audit; Clarke to head Investor Relations
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:9/17/2014)... University] As Congress adjourns this month for the ... step over on their way out the chamber door ... Medicare Provider Payment Modernization Act of 2014. In a ... Dr. Eli Adashi recounts what he and other advocates ... The perennial trouble with how Medicare pays doctors will ...
(Date:9/17/2014)... 17, 2014 Wright hip lawsuit ... of metal-on-metal hip replacements continue to grow in ... Court, Northern District of Georgia, Bernstein Liebhard LLP ... by the U.S. Judicial Panel on Multidistrict Litigation ... liability claims have been filed in the proceeding ...
(Date:9/17/2014)... 2014 Boston Children’s Museum and ... monthly concert series, introducing young Museum visitors to ... America’s premier national platform celebrating the stories, talents, ... the young musicians featured will also be showcased ... Museum is fortunate to partner with the wonderful ...
(Date:9/17/2014)... Austin, TX (PRWEB) September 17, 2014 ... the Editor’s Picks by Progressive Grocer, a leading trade ... Pizza was awarded for originality and flavor, among other ... featured as an Editor’s Pick in the September print ... Progressive Grocer website. , The pizza won based on ...
(Date:9/17/2014)... 17, 2014 StartX , a ... companies raising rounds of funding at its Summer Demo ... investors and media, was the first such gathering held ... to the university. The presentations were delivered on an ... StartX-QB3 Labs, a 2,000 square foot life science facility ...
Breaking Medicine News(10 mins):Health News:Failed Medicare payments law remains relevant 2Health News:Failed Medicare payments law remains relevant 3Health News:Wright Hip Lawsuit News: Nearly 400 Filings Reported in Federal Wright Conserve Hip Replacement Litigation, Bernstein Liebhard LLP Reports 2Health News:Wright Hip Lawsuit News: Nearly 400 Filings Reported in Federal Wright Conserve Hip Replacement Litigation, Bernstein Liebhard LLP Reports 3Health News:Boston Children's Museum Partners with From the Top to Offer Monthly Concert Series 2Health News:Boston Children's Museum Partners with From the Top to Offer Monthly Concert Series 3Health News:Smart Flour Foods Wins 2014 Progressive Grocer Editor’s Pick Award 2Health News:Stanford-affiliated StartX Showcases Startups, New HQ, and Growth of Stanford-StartX Fund 2Health News:Stanford-affiliated StartX Showcases Startups, New HQ, and Growth of Stanford-StartX Fund 3Health News:Stanford-affiliated StartX Showcases Startups, New HQ, and Growth of Stanford-StartX Fund 4Health News:Stanford-affiliated StartX Showcases Startups, New HQ, and Growth of Stanford-StartX Fund 5Health News:Stanford-affiliated StartX Showcases Startups, New HQ, and Growth of Stanford-StartX Fund 6
... Veto Will Deprive Six Million American Children of Healthcare ... of,Child and Adolescent Psychiatry strongly urges Congress to override,President ... 976) act., The House passed the S-CHIP bill ... enough to override the President,s veto. The Senate passed ...
... Pam Brady,President of the California State PTA, ... federal legislation to expand the State,Children,s Health Insurance ... morning of legislation to expand the SCHIP,program is ... families,including approximately 800,000 in California, who need medical ...
... Oct. 3 Prominent cosmetic dentist Dr. William,Hoskyns has ... partner.,Dr. Hoskyns joins Dr. Debra Gray King and her ... Arizona where he had an international,reputation as the dentist ... reconstruction. Well known for his celebrity and high ...
... Medical,Technologies, Inc. (Nasdaq: VNUS ), a leading provider ... reflux disease, today,announced that it presented at the William ... ET on October 3, 2007, at the New York,Palace ... of the VNUS presentation webcast is available on the,corporate ...
... Effective in High Risk Angioplasty Patients, TORONTO, ... over the,past year about the safety and potential ... possible fatal blood clots, even years,after an angioplasty ... from Ontario,s Institute for Clinical Evaluative Sciences,(ICES) and ...
... 3 The American Health Information,Management Association ... assessment and training consultation services for the,Centers ... AHIMA,s signing of,a contract with the nation,s ... requires AHIMA to determine ICD-10,s,impact(s) on CMS; ...
Cached Medicine News:Health News:American Academy of Child and Adolescent Psychiatry Reacts to S-CHIP Veto 2Health News:Prominent Cosmetic Dentist Dr. William Hoskyns Joins Leading Atlanta Practice 2Health News:New Canadian study finds drug coated heart stents to be safe: 2Health News:New Canadian study finds drug coated heart stents to be safe: 3Health News:New Canadian study finds drug coated heart stents to be safe: 4Health News:AHIMA Signs Contract With CMS for ICD-10 Implementation Assessment and Training 2
(Date:9/17/2014)... NEW YORK , Sept. 17, 2014  Levi ... ALXA) in connection with possible claims of breaches of ... Company. To get more information, click here: ... to you. If you own common stock ... information, please contact Eduard Korsinsky, Esq. either ...
(Date:9/17/2014)... Sept. 17, 2014 /PRNewswire-iReach/ -- ChemImage announced ... discussing improvements in the development of imaging ... both normal and diseased tissue that minimizes ... surgical procedures, lowers surgical costs and potentially ... The clinical and scientific ...
(Date:9/17/2014)... 2014 Bronstein, Gewirtz & Grossman, LLC is ... securities of PDL BioPharma, Inc. ("PDL BioPharma" or the ... are advised to contact Peretz Bronstein or ... info@bgandg.com or 212-697-6484. The investigation ... executives violated federal securities laws. On September ...
Breaking Medicine Technology:Patient Outcomes Improve When Molecular Chemical Imaging Technology Is Used to Aid Robotic Surgical Procedures, According to New White Paper 2Shareholder Alert: Bronstein, Gewirtz & Grossman, LLC Investigates claims on behalf of Investors of PDL BioPharma, Inc. --PDLI 2
... Feb. 21, 2012 A collaboration between NineSigma and ... advance HIV vaccine research by identifying new approaches to ... provider of innovation services , NineSigma has connected ... and helped it identify two scientists who will receive ...
... #8116 -- Precyse, a leader in health information ... HIMSS 2012 Annual Conference and Exposition that the ... improvements in revenue cycle workflow, coding accuracy, and ... adopting Precyse,s integrated health information management (HIM) and ...
Cached Medicine Technology:IAVI and NineSigma Collaborate to Identify New Approaches to Developing AIDS Vaccines 2IAVI and NineSigma Collaborate to Identify New Approaches to Developing AIDS Vaccines 3IAVI and NineSigma Collaborate to Identify New Approaches to Developing AIDS Vaccines 4Growing List of Providers Accelerate Revenue Cycles, Improve Clinical Documentation Through True Computer-Assisted Coding with Natural Language Comprehension™ 2Growing List of Providers Accelerate Revenue Cycles, Improve Clinical Documentation Through True Computer-Assisted Coding with Natural Language Comprehension™ 3Growing List of Providers Accelerate Revenue Cycles, Improve Clinical Documentation Through True Computer-Assisted Coding with Natural Language Comprehension™ 4
... The Vitros ECi brings true ... to immunodiagnostic testing. Highly sensitive assays ... oncology and bone metabolism testing are ... under development. The Vitros ECi can ...
... is a flexible system that ... environments small hospitals, backup ... satellite locations. The Vitros 250 ... can be automated or placed ...
... an effort to improve on the ... toxicology, abused drugs, and immunosuppressants tests, ... which incorporates random access capabilities. Although ... undergone several important changes in the ...
The IMx system is an automated analyzer designed to perform microparticle enzyme immunoassay (MEIA), fluorescence polarization immunoassay (FPIA) and ion capture technologies....
Medicine Products: