Navigation Links
Analysis Finds Clinical Trials Often Small, of Poor Quality
Date:5/2/2012

By Randy Dotinga
HealthDay Reporter

TUESDAY, May 1 (HealthDay News) -- A new analysis of registered U.S. clinical trials -- the research that seeks to determine if medical treatments and prevention strategies work -- finds that many are small and of poor quality.

Studies of cancer treatments, in particular, often fail to follow the highest standards of medical research, the analysis found. Meanwhile, a full 7 percent of the studies didn't bother to mention their purpose, while others failed to provide other important details.

"We think expert groups need to start scrutinizing the database more and really examine the quality of the trials one by one," said report author Dr. Robert Califf, vice chancellor for clinical and translational research at Duke University. "For the first time, we have a chance to look at the entire universe [of clinical research] and we can see that we can do better."

Califf and his colleagues examined the Clinicaltrials.gov database, which includes medical research studies that enroll people. By law in the United States, many kinds of studies must be registered in this database.

As the law has been strengthened, the number of registered trials has grown. A total of 40,970 trials were registered between October 2007 and September 2010, compared to 28,881 trials registered over the previous three years.

"In the past, there would be a lot of studies done, but many would never be studied or reported anywhere," Califf explained. "Sometimes you'd only see the ones that were positive. Now, we have much more accurate information."

However, the analysis found that most clinical research in the database isn't very extensive, raising questions about reliability.

The new report says 62 percent of the trials from 2007-2010 were small, with 100 or fewer participants. Only 4 percent had more than 1,000 participants.

"There are 330 new clinical trials being registered every
'/>"/>

Copyright©2010 ScoutNews,LLC.
All rights reserved  

Page: 1 2 3

Related medicine news :

1. Kaiser Analysis Finds Record Medicaid Enrollment Growth in 2009
2. New approach to immune cell analysis seen as first step to better distinguish health and disease
3. National Center for Policy Analysis and Salem Radio Network Deliver One Million Emails to Congress to Stop ObamaCare
4. Pregnancy for breast cancer survivors: Meta-analysis reveals it is safe and could improve survival
5. Improved device provides more rapid, comprehensive analysis of circulating tumor cells
6. Know What Works with Semantic Design's Test Coverage Analysis Tool for C#/.Net
7. Social Media Network Analysis Workshop
8. University of Miami College of Engineering to develop new methods for data analysis
9. Biosensor chip enables high-sensitivity protein analysis for disease diagnosis
10. MetaGeek Announces Chanalyzer Pro Spectrum Analysis Software for Wi- Spy, Adds Device Classification, Device Finder and Automated Reports
11. Voice Analysis May Allow Early Detection of Parkinsons
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Analysis Finds Clinical Trials Often Small, of Poor Quality 
(Date:4/28/2015)... (PRWEB) April 28, 2015 Dead or damaged ... and their property. In many cases, tree removal by a ... way to eliminate the threat. , In their ... of tree removal available to property owners today. Each method ... for a job well done. , The article states that, ...
(Date:4/28/2015)... (PRWEB) April 28, 2015 Once considered an ... Lights have taken the industry by storm with perfectly tailored ... use unit. , More than half of every ... KIND LED , proving the stigma is gone and LED ... overwhelming positive response from customers and their first hand experience ...
(Date:4/28/2015)... 2015 The Awareness Counselor team has introduced ... of judging. According to Awareness Counselor, there are ramifications of ... outward, and to an individual who self-judges. This new concept ... a class or one one one talk. , The premise ... Counselor, is that every being on earth is here for ...
(Date:4/28/2015)... 28, 2015 LifeAID® Beverage ... convenient nutrition for every lifestyle, announced today ... United Natural Foods Inc (UNFI), the leading ... specialty foods including nutritional supplements. FitAID®, GolferAID® ... thousands of retailers and consumers through the ...
(Date:4/27/2015)... Churchview Supportive Living, a Gardant affordable assisted living community, ... from 10:30 a.m. to noon on May 8. , ... St. in Chicago, serves low-income older adults, including those ... independence. , “Mothers, grandmothers, godmothers and mothers-to-be are invited ... Director of Marketing Elizabeth Clippard. , The menu will ...
Breaking Medicine News(10 mins):Health News:Tree Removal Methods and Services Discussed in Recent Article by Precision Tree Services 2Health News:SuperCloset Reports Surge in KIND LED Grow Light Sales, Saving Indoor Growing Enthusiasts up to 40% on their Power Usage. 2Health News:What Happens When We Judge Ourselves and Others? – A New Concept Introduced 2Health News:What Happens When We Judge Ourselves and Others? – A New Concept Introduced 3Health News:LifeAID Beverage Co. Announces Expanded Distribution Roll Out Through UNFI -- United Natural Foods Inc. 2Health News:LifeAID Beverage Co. Announces Expanded Distribution Roll Out Through UNFI -- United Natural Foods Inc. 3Health News:Churchview Supportive Living Community in Chicago to Host Mother's Day Brunch 2
... 7-9 in Las Vegas , ... Denver -- As part of its ... Water Works Association (AWWA), the authoritative resource on safe water, today ... , Oct. 7-9, 2009, in Las Vegas., , , , ,Debuted last ...
... comes as use of stimulant for enhanced mental function is ... -- A drug used to treat narcolepsy is increasingly being ... evidence that it also harbors the potential for abuse. , ... brain, the new study shows. , "This drug does seem ...
... Carestream Health, Inc. is a leading provider of dental and medical ... ... NY (PRWEB) March 17, 2009 -- Carestream Health, Inc., announced new ... (DR) imaging systems that provide direct digital capture of medical x-ray ...
... The Netherlands A number of updated guidelines will be ... of Urology (EAU) held in Stockholm, from 17 though 21 ... based on the extended text documents will also be available ... of clinical guidelines is one of the core activities of ...
... Ill., March 17 It happens in an instant, standing ... Vice President Joe Biden,s mother. For 92 year old ... guarding against taking a tumble is fast becoming a full ... now take added precautions to help prevent a fall and ...
... tobacco, and drug useOLYMPIA, Wash., March 17 A ... good choices about their health. Still, far too many ... behavior.The Healthy Youth Survey focuses on health risk behaviors. ... by more than 210,000 public school kids around the ...
Cached Medicine News:Health News:AWWA partners with WaterSmart Innovations conference 2Health News:Narcolepsy Drug Might Be Addictive 2Health News:Narcolepsy Drug Might Be Addictive 3Health News:Carestream Health Announces New Orders From from U.S. Healthcare Facilities For for Its Digital Radiography Solutions 2Health News:EAU launches new clinical guidelines for 2009 -- kidney cancer 2Health News:Safety Alert: From the American Academy of Orthopaedic Surgeons 2Health News:New Survey Results Give a Window Into Teen Behavior and Risks 2Health News:New Survey Results Give a Window Into Teen Behavior and Risks 3
(Date:4/27/2015)...   Intarcia Therapeutics, Inc. today announced the ... an equity conversion option at a $5.5 billion Company ... the initiation of additional head-to-head comparative and switch studies ... 2 diabetes therapies. In addition, proceeds from the financing ... launch ITCA 650 in the United States ...
(Date:4/27/2015)... 2015 Array BioPharma Inc. (Nasdaq: ... third quarter of fiscal 2015 and hold ... on Monday, May 4, 2015.  Ron Squarer, ... May 4, 2015Time:9:00 a.m. Eastern TimeToll-Free:(844) 464-3927Toll:(765) ... Conference Call Slides:  http://edge.media-server.com/m/p/8tsxszuw/lan/en ...
(Date:4/27/2015)... THE WOODLANDS, Texas , April 27, 2015 /PRNewswire/ ... a biopharmaceutical company focused on developing breakthrough treatments for ... results on Wednesday, April 29, 2015 after the financial ... and webcast to discuss clinical development progress and financial ... Eastern Time on April 29, 2015. The ...
Breaking Medicine Technology:Intarcia Therapeutics Closes Novel $225 Million Synthetic Royalty Financing With Equity Conversion Option At $5.5 Billion Valuation 2Intarcia Therapeutics Closes Novel $225 Million Synthetic Royalty Financing With Equity Conversion Option At $5.5 Billion Valuation 3Lexicon To Report First Quarter 2015 Financial Results On April 29, 2015 2
... ARUP Laboratories is a national reference ... laboratory research and development. ARUP offers an ... unique medical tests in clinical and anatomic ... ARUP Laboratories' clients include more than half ...
... national reference laboratory and a worldwide leader ... offers an extensive test menu of highly ... and anatomic pathology. Owned by the University ... than half of the nation's university teaching ...
... is a national reference laboratory and a ... development. ARUP offers an extensive test menu ... in clinical and anatomic pathology. Owned by ... include more than half of the nation's ...
... Laboratories is a national reference laboratory and ... and development. ARUP offers an extensive test ... tests in clinical and anatomic pathology. Owned ... clients include more than half of the ...
Medicine Products: