Navigation Links
Anadys Pharmaceuticals Reports Fourth Quarter and Year-End 2008 Financial Results and Highlights
Date:2/26/2009

in 2007.

Development Program Highlights

ANA598

ANA598 is an investigational oral non-nucleoside polymerase inhibitor that Anadys is developing for the treatment of chronic hepatitis C virus (HCV) infection. ANA598 has recently demonstrated potent antiviral activity at the first dose level in an ongoing short-term study in HCV patients. The magnitude of viral load decline seen at the first dose level was greater than has been reported for any other non-nucleoside polymerase inhibitor in a monotherapy study. A number of clinical, toxicology and manufacturing activities are underway which, if successful in the short-term, should position ANA598 to be ready in mid-2009 for Phase II studies in combination with current standard of care. In December 2008, Anadys announced that the U.S. Food and Drug Administration granted Fast Track Designation to ANA598 as a treatment for chronic HCV infection.

  • Antiviral Potency of ANA598 in HCV. In the first quarter of 2009, Anadys announced results from the first dose level in an ongoing Phase Ib clinical trial of ANA598 over three days. The median viral load decline at the end of treatment was 2.4 log10 (with a range of 0.4-3.4 log10) for the eleven patients who received ANA598 at 200 mg twice-daily (bid). The five genotype 1a patients who received ANA598 demonstrated a median viral load decline of 1.5 log10, while the six genotype 1b patients who received ANA598 demonstrated a median viral load decline of 2.6 log10. No patients demonstrated viral rebound while on study drug. ANA598 was very well tolerated at 200 mg bid and no serious adverse events were reported, although conclusions regarding longer-term safety and tolerability cannot be made until the results of future clinical trials of longer duration in more patients are known. Enrollment has been completed in the 400 mg bid and 800 mg bid cohorts. The Comp
    '/>"/>

SOURCE Anadys Pharmaceuticals, Inc.
Copyright©2009 PR Newswire.
All rights reserved

Page: 1 2 3 4 5 6 7 8 9 10

Related medicine news :

1. Anadys Pharmaceuticals to Present at BIO InvestorForum 2007
2. Anadys Pharmaceuticals to Present at Bio Investor Forum
3. Anadys Pharmaceuticals Commences Dosing ANA598 in Hepatitis C Patients in Phase Ib Study
4. Anadys Pharmaceuticals to Present at the BIO CEO & Investor Conference
5. Anadys Pharmaceuticals to Report Fourth Quarter and Year End 2008 Financial Results
6. Arena Pharmaceuticals to Present at the NewsMakers in the Biotech Industry Conference
7. Schering-Plough/Merck Pharmaceuticals Announce FDA Filing Acceptance of New Drug Application for Loratadine/Montelukast Tablet
8. Provectus Pharmaceuticals, Inc. Begins Phase 2 Clinical Trial for Metastatic Melanoma
9. Idenix Pharmaceuticals to Present at Two Upcoming Investor Conferences
10. Vista Partners Updates Coverage on Tapestry Pharmaceuticals
11. Transcept Pharmaceuticals, Inc. to Present at UBS 2007 Global Life Sciences Conference
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:7/31/2015)... , ... July 31, 2015 , ... ... Times magazine. What are the STASH awards? The Significant Technological Achievements in ... the cannabis-cultivation community as well as tried-and-true products that have stood the test ...
(Date:7/31/2015)... New York (PRWEB) , ... July 31, 2015 , ... ... strut their stuff, Super-Sod debuted their new type of sod called Leisure Time(TM) ... trademark application in process. , To commemorate introduction of this new type of sod, ...
(Date:7/31/2015)... ... ... Bowl 50 will emanate from Levi’s Stadium in Santa Clara, CA on Sunday, February ... In the two weeks that separate the conference championships and the Super Bowl, there is ... will mark the 50th time it has been held and the festivities will take place ...
(Date:7/31/2015)... , ... July 31, 2015 , ... Precision Aesthetics is ... years. It was also the first provider of Exilis non-surgical fat reduction in ... after procedures it has attracted a large International clientele. Many patients travel to ...
(Date:7/31/2015)... ... July 31, 2015 , ... ... run by GoodThreads. The store can be accessed by visiting http://www.curemeso.org/store . ... which are customizable. The best part: whenever a product is purchased, the Meso ...
Breaking Medicine News(10 mins):Health News:The High Times S.T.A.S.H. Awards Are in, Guess Who Took Home the Prize for “Best Grow System” 2Health News:Super-Sod Introduces Leisure Time(TM) Zoysia Grass with an Adirondack Chair Promotion 2Health News:Cheap 2016 Super Bowl Tickets at Levi's Stadium: Ticket Down Slashes Ticket Prices on Super Bowl 50 Tickets in Santa Clara, CA at Levi's Stadium 2Health News:Mesothelioma Organization Launches New Store 2Health News:Mesothelioma Organization Launches New Store 3
... A new study by researchers at the University of Southern ... , Researchers found that a storyline on the primetime ... and healthy eating habits had a positive impact on the ... study, published in the Sept. 14 Journal of Health Communication ...
... warning, experts say , SATURDAY, Sept. 22 (HealthDay News) ... be so silent, experts say. , That,s why women ... to possible symptoms of ovarian cancer, according to a ... who are trying to increase awareness about the disease. ...
... have worked hard to get into,summer shape, but now ... may have taken a toll on our waistlines. Now ... into the one thing that will never lie to,us. ... Registered journalists can access video, audio, text, ...
... WASHINGTON, Sept. 21 The following is a,statement ... on Budget,and Policy Priorities, on the new congressional ... coverage to several million,low-income uninsured children, a major ... the children who would gain coverage are poor,and ...
... to persist, experts say, , , FRIDAY, Sept. 21 (HealthDay News) -- ... passage. But new research suggests it has a darker side, one ... start to drink at a younger age more likely to develop ... to be in motor vehicle crashes and to be in fights," ...
... Scientists at Johns Hopkins recently discovered that a chemical ... from insects to humans could mean the difference between ... Sept. 21 issue of Cell, describes how organs can ... reaction is perturbed. , This chain reaction, a ...
Cached Medicine News:Health News:ER episode impacts viewers' health knowledge and behavior 2Health News:Pelvic Exams Can Help Spot Ovarian Cancer 2Health News:Statement by Robert Greenstein, Executive Director of the Center on Budget and Policy Priorities, on the New Congressional SCHIP Agreement 2Health News:Teenage Drinking Can Spell Lasting Trouble 2Health News:Teenage Drinking Can Spell Lasting Trouble 3Health News:Controlling for size may also prevent cancer 2
(Date:7/31/2015)... , July 31, 2015  In today,s ever-changing marketplace, ... are increasingly mobile, increasingly connected, and increasingly impatient with ... of customer interaction channels and tools is driving call ... media. According to research by benchmarking ... counter (OTC) segment in a call center study realize ...
(Date:7/31/2015)... , July 31, 2015 More than 1,500 ... country will convene in Indianapolis ... 2015 Mid-Year Training Institute . The week-long training, ... to address one of our nation,s biggest public health ... Mid-Year Training Institute is a one-of-a-kind intensive training opportunity, ...
(Date:7/31/2015)... , July 31, 2015 ... 2015 market research report that provides an overview ... using data sourced from in-house databases, secondary and ... and needles market products pipeline spread across 124 ... with 73 tables and 5 figures is now ...
Breaking Medicine Technology:Best Practices in Building World-Class Consumer & Over-the-Counter Call Centers 2Community Leaders From Across The Country Head To Indianapolis For CADCA 2015 Mid-Year Training Institute Aug. 2-6 2Syringes and Needles Market Products Pipeline Review 2015 Report 2Syringes and Needles Market Products Pipeline Review 2015 Report 3Syringes and Needles Market Products Pipeline Review 2015 Report 4Syringes and Needles Market Products Pipeline Review 2015 Report 5
... 2011   Radiotherapy Clinics of Georgia has announced the ... physicians of Radiotherapy Clinics of Georgia in January.  These courses ... and treatment options. All Prostate Cancer Lecture Series ... a light dinner at 5 p.m. followed by a lecture ...
... Md., Dec. 16, 2011 The U.S. Food and Drug ... heart of children with heart failure to help keep them ... found. (Logo: http://photos.prnewswire.com/prnh/20090824/FDALOGO ) ... Pediatric System, made by a German company, Berlin Heart. The ...
Cached Medicine Technology:Radiotherapy Clinics of Georgia Present Prostate Cancer Lecture Series 2FDA Approves Mechanical Cardiac Assist Device for Children With Heart Failure 2FDA Approves Mechanical Cardiac Assist Device for Children With Heart Failure 3
Kelman - McPherson tying forceps with serrated handle, platform 4 mm and overall length of 85 mm....
Castroviejo tying forceps, straight....
Moria tying forceps are straight, very delicate platforms for 10-0 and 11-0 monofilament. Platforms fully meet to hold suture firmly....
Fine tying forceps, standard with smooth jaws. For 7-0 to 9-0 sutures....
Medicine Products: