Navigation Links
Anadys Pharmaceuticals Commences Dosing ANA598 in Hepatitis C Patients in Phase Ib Study
Date:10/28/2008

SAN DIEGO, Oct. 28 /PRNewswire-FirstCall/ -- Anadys Pharmaceuticals, Inc. (Nasdaq: ANDS) announced today that it has initiated dosing ANA598 in patients chronically infected with hepatitis C virus (HCV) in a Phase Ib study. ANA598 is an investigational, oral, non-nucleoside polymerase inhibitor. The Phase Ib clinical trial is a double-blind, placebo-controlled study that will evaluate the tolerability, pharmacokinetics and viral kinetics of multiple, ascending doses of ANA598 over a period of three days. Anadys expects to enroll approximately 30 patients in the study of ANA598 at doses of 200 mg bid (twice-a-day), 400 mg bid and 800 mg bid.

"ANA598 demonstrated favorable tolerability and pharmacokinetics as a single dose in healthy volunteers in our recently concluded Phase I study," said James Freddo, M.D., Anadys' Senior Vice President, Drug Development and Chief Medical Officer. "We look forward to building upon these results and testing the compound in HCV patients, first in this monotherapy study and subsequently in combination studies. We expect the maximal benefit of direct antivirals to be realized when used in combination regimens incorporating multiple anti-HCV agents."

ANA598 Phase Ib Study

In the Phase Ib monotherapy study, ANA598 will be administered to naive genotype 1a and 1b patients over three days, at doses of 200 mg bid, 400 mg bid or 800 mg bid. Ten patients are planned to be enrolled in each of the three cohorts - eight on active treatment and two on placebo. Anadys expects to have viral load data from all three cohorts in the first quarter of 2009. Anadys may elect to explore other dose levels of ANA598 and/or once-daily dosing based on data from the first three cohorts.

About ANA598

<
'/>"/>
SOURCE Anadys Pharmaceuticals, Inc.
Copyright©2008 PR Newswire.
All rights reserved

Page: 1 2 3 4 5

Related medicine news :

1. Anadys Pharmaceuticals to Present at Bio Investor Forum
2. Anadys Pharmaceuticals to Present at BIO InvestorForum 2007
3. Idenix Pharmaceuticals to Present at Two Upcoming Investor Conferences
4. Alexion Pharmaceuticals Chooses Blue Mountain Regulatory Asset Manager(R) for Best-in-class Calibration Management Integrated with SAP(R)
5. Perrigo Company Licenses Prescription Brands to Medimetriks Pharmaceuticals
6. CoLucid Pharmaceuticals Names Linda Hogan VP of Business Development
7. Memory Pharmaceuticals Announces Issuance of Key U.S. Patent for R3487/MEM 3454 and R4996/MEM 63908
8. Access Pharmaceuticals Presents ProLindac(TM) Data at the AACR-NCI-EORTC Symposium 2008
9. Avidas Pharmaceuticals Signs Agreement to Acquire North American Rights to Products That Address Chronic Dermatologic Conditions
10. Genesis Pharmaceuticals Received New Purchase Orders Worth $12 Million
11. ISTA Pharmaceuticals to Present at the Thomas Weisel Partners Healthcare Conference 2008
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:11/28/2014)... 2014 Secura Consultants, based in ... marketing organizations in the country focused on delivering ... marketplace. Secura Consultants is proud to offer complimentary ... Group, a leading global financial company. , Many ... the ownership interest comes the need for business ...
(Date:11/28/2014)... 28, 2014 Not only is the ... free of petroleum, parabens and other cancer-causing agents, but ... research, education and awareness programs that help in the ... owners have raised an incredible, record-breaking contribution of $30,000 ... sales of the Sweet Red Rose Whip Moisturizer and ...
(Date:11/28/2014)... New York, New York (PRWEB) November 28, 2014 ... lawsuits ( http://www.consumerinjurylawyers.com/stryker-rejuvenate/stryker-hip-lawsuits/ ) have now been filed ... pair of recalled metal implants, Bernstein Liebhard LLP ... November 18th in Bergen County Superior Court reflects ... and ABG II modular-neck hip stems, which were ...
(Date:11/28/2014)... "Most of my life, I have suffered from foot issues ... from Findlay, Ohio. "I thought that there had to be ... inspired me to invent this accessory." , She developed the ... an injured foot. The sling makes it easier for the ... The design redistributes weight so that the individual does not ...
(Date:11/28/2014)... November 28, 2014 talklocal ( ... to the right service professionals by phone in about 90 ... at least two tornadoes were reported to have touched down ... damage was reported following the tornadoes, Denver residents now know ... unexpected. Having TalkLocal is like having local pros in over ...
Breaking Medicine News(10 mins):Health News:Secura Consultants Offers Complimentary Buy-Sell Agreement Reviews 2Health News:Éminence Organic Skin Care Donates Record-breaking $30,000 to Breast Cancer Research 2Health News:Éminence Organic Skin Care Donates Record-breaking $30,000 to Breast Cancer Research 3Health News:More than 2,100 Stryker Hip Lawsuits Included in New Jersey Litigation after Settlement Announcement, Bernstein Liebhard LLP Reports 2Health News:More than 2,100 Stryker Hip Lawsuits Included in New Jersey Litigation after Settlement Announcement, Bernstein Liebhard LLP Reports 3Health News:TalkLocal Launches In Denver A Week After Multiple Tornadoes Hit Near City 2
... ... its remarkable success in alcohol recovery, National Institute For Alcohol Recovery (NIFAR®) is launching ... , ... (PRWEB) December 29, 2009 -- On the heels of its remarkable success in alcohol ...
... Health gurus say recommit each Monday until the habit is gone ... millions of Americans will resolve to quit smoking -- again. Yet many ... and the American Cancer Society say it doesn,t have to be that ... quit again the following Monday. And recommit to stay quit each Monday ...
... 29 TeamStaff, Inc. (Nasdaq: TSTF ), ... Government, today announced that it has reached a definitive agreement ... healthcare subsidiary, TeamStaff Rx, Inc. to Advantage RN, LLC. TeamStaff ... structured as an all cash purchase which is expected to ...
... ... Housewives of Orange County ,” Dr. Milind Ambe consulted with Lynne Curtin’s teen-age daughter ... breast augmentation with the 19 year-old. , ... (Vocus) December 29, 2009 -- Newport Beach plastic surgeon, ...
... ... growing companies , ... (PRWEB) December 29, 2009 -- Lexi-Comp, Inc., a leader in providing drug and clinical information ... 2009 Weatherhead 100 list that showcases the fastest growing companies in Northeast Ohio. ...
... NEWPORT BEACH, Calif., Dec. 28 With the New Year just ... resolutions. , , Lose weight., ... underlying theme of most New Year,s resolutions is health-related, many tend ... visits to the doctor. Even more so, we forgo the regular ...
Cached Medicine News:Health News:Now Millions Suffering With Alcohol Addiction Can Get Breakthrough Recovery in Ultimate Privacy 2Health News:Now Millions Suffering With Alcohol Addiction Can Get Breakthrough Recovery in Ultimate Privacy 3Health News:This New Years, Smokers Get 52 Chances to Stay Quit 2Health News:TeamStaff Announces Agreement to Sell Its Travel Healthcare Subsidiary 2Health News:TeamStaff Announces Agreement to Sell Its Travel Healthcare Subsidiary 3Health News:Newport Beach Plastic Surgeon Educates About the Pros and Cons of Plastic Surgery 2Health News:Newport Beach Plastic Surgeon Educates About the Pros and Cons of Plastic Surgery 3Health News:Lexi-Comp, Inc. Receives Weatherhead 100 Honor 2Health News:Celebrate the New Year With a New You 2
(Date:11/26/2014)...  Cohen, Placitella & Roth, PC is investigating ... Nymox Pharmaceutical Corporation ("Nymox" or "Company") (NASDAQ: ... 31, 2011 through November 2, 2014 ("Class Period").  ... its officers and directors publically disseminated materially false ... and 20(a) of the Securities Exchange Act of ...
(Date:11/26/2014)... VIEJO, Calif. , Nov. 26, 2014 /PRNewswire/ ... announced that the U.S. Food and Drug Administration ... its New Drug Application (NDA) for AVP-825. AVP-825 ... low-dose sumatriptan powder delivered intranasally utilizing a novel ... the Complete Response letter, and consistent with the ...
(Date:11/26/2014)...  BioScrip ® , Inc. (NASDAQ: BIOS ) announced ... Officer, will present at the Bank of America Merrill Lynch 2014 ... Date: , , , Wednesday, December 3, 2014 , , ... , , , Location: , , , Boca Raton Resort and ... BioScrip, Inc. is a leading national provider ...
Breaking Medicine Technology:Cohen, Placitella & Roth, PC Investigating Nymox Pharmaceutical Corporation for Failing to Disclose Material Information 2Cohen, Placitella & Roth, PC Investigating Nymox Pharmaceutical Corporation for Failing to Disclose Material Information 3Avanir Pharmaceuticals Receives Complete Response Letter (CRL) from FDA on AVP-825 NDA 2Avanir Pharmaceuticals Receives Complete Response Letter (CRL) from FDA on AVP-825 NDA 3Avanir Pharmaceuticals Receives Complete Response Letter (CRL) from FDA on AVP-825 NDA 4
... Craneware, Inc., the market leader in automated revenue ... with Kingman Regional Medical Center, a 235-bed non-profit ... of the nation,s five star hospitals in community ... InSight Denials® to the range of Craneware Revenue ...
... Vanda Pharmaceuticals Inc. (Vanda) (NASDAQ: VNDA ), ... of products for central nervous system disorders, today announced ... will deliver a corporate presentation on Thursday, June 9, ... will take place as part of the Jefferies 2011 ...
Cached Medicine Technology:Kingman Adds Craneware Revenue Integrity Solution - InSight Denials® 2Kingman Adds Craneware Revenue Integrity Solution - InSight Denials® 3Kingman Adds Craneware Revenue Integrity Solution - InSight Denials® 4
Pediatric model. Spring-controlled spread of blades with locking mechanism. Dull finish. Blades: 11 mm....
Solid 14 mm free-swinging blades, suture posts, and stabilizing disk. Dull finish....
Double bent ends prevent wire from catching when pushed forward. Designed for use with the Castroviejo Snare (E3675). Package of 12 stainless steel wires. Overall length 4.3 inches....
... be used only with the E3671 twisted snare ... the wing nut and the loop can be ... ratchet so that the loop can be slipped ... length - 5.6 inches. Comes with one package ...
Medicine Products: