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An international study identifies new DNA variants that increase the risk for cancer
Date:3/27/2013

Benítez concludes: "Every tumour is born with its own distinct genetic history, so if we identify those individuals whose genetic characteristics confer them a greater probability of developing cancer, we will be able to provide them with more adequate follow-up and thus reduce the appearance of the disease or diagnose it in its initial phases."

The collaborative effort of thousands of national and international scientists has opened new perspectives for cancer research, offering new clues to the understanding of the molecular pathways in cancer cells. These studies could also expand the possibilities in the search for new therapeutic treatments against cancer.

The CNIO, in addition to coordinating the genotyping of tumours, has also taken part in the genotyping of breast cancer studies via the National Genotyping Centre-Instituto de Salud Carlos III (CeGen-ISCIII), in collaboration with Anna González-Neira, Head of the Human Genotyping- CEGEN Core Unit as well as in the corresponding data analysis with the help of Roger Milne from the Human Genetics Group and Ana Osorio from the Genetic and Molecular Epidemiology Group. This work has been made possible thanks to the collaboration of the Monte Naranco hospital in Oviedo and the La Paz hospital in Madrid.

About COGS

The main aims of the European COGS project are directed towards the study of the genetic and environmental factors that predispose people to the appearance of breast, prostate and ovarian cancers, the most common forms of cancer in developing countries, and towards how society might benefit from such results.

The European COGS project is the result of the collaboration between four international consortiums: BCAC, whose aim is to study breast cancer; PRACTICAL, which researches genetic alterations associated with prostate cancer; OCAC, whose aim is to study ovarian cancer, and CIMBA, which studies BRCA1 and BRCA2 modifications.'/>"/>

Contact: Nuria Noriega
comunicacion@cnio.es
Centro Nacional de Investigaciones Oncologicas (CNIO)
Source:Eurekalert

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