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An individualized approach to breast cancer treatment
Date:1/26/2009

resulting from lung and brain cancer, and could be used to respond to a wide spectrum of neurodegenerative diseases, such as Alzheimer's, Dr. Tsarfaty reports.

Dr. Tsarfaty's MRI-and-ultrasound-imaging application monitors the metabolic changes that occur during cancer metastasis. Increased blood flow (which can be sensed by ultrasound) and an increase of oxygen consumption (measured with an MRI) can indicate cancer metastasis with unprecedented levels of sensitivity.

Normally scientists look for structural changes in the body, such as the presence of a tumor. But with their new methods, Dr. Tsasfaty and his team which includes his wife, a radiologist are actually able to "see" cancer metastasis within a small group of cells long before the cancer spreads to other organs in the body.

Earlier Detection, Earlier Treatment

"Today, clinicians only diagnose cancer when they see a tumor several millimeters in size. But our diagnosis can be derived from observing only a few cells, and looks specifically at the activation levels of a protein called Met. Activated Met is an oncogen," he says. "If the tumor cells show activation of Met, we can design personalized medicine to treat a specific kind of breast cancer."

At Tel Aviv University, Dr. Tsarfaty is now working to establish a Molecular Imaging Center one of the first to encompass a multi-discipline approach to cancer imaging and treatment. The Breast Cancer Research Foundation of America supports his research.


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Contact: George Hunka
ghunka@aftau.org
212-742-9070
American Friends of Tel Aviv University
Source:Eurekalert  

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