Navigation Links
An ideal therapy for peptic ulcer disease
Date:11/11/2008

Since the discovery of the etiological role of Helicobacter pylori (H pylori) in peptic ulcer disease, its eradication became the main objective of therapy, and several treatment regimens were developed. Currently, triple therapy with omeprazole, amoxicillin, and clarithromycin remains the best therapeutic option. Despite its efficacy, 10% to 20% of the patients present with treatment failure, demanding alternative therapeutic regimes with variable success rates. The development of effective salvage treatments is of paramount importance in this situation.

The research team led by Jaime Natan Eisig, from Brazil addresses this question and this will be be published on October 28; 2008 in the World Journal of Gastroenterology.

The therapeutic regimen consisted of 20 mg omeprazole, 240 mg colloidal bismuth subcitrate, 1000 mg amoxicillin, and 200 mg furazolidone, taken twice a day for seven days. Patients were considered as eradicated when samples taken from the gastric antrum and corpus twelve weeks the end of treatment were negative for H pylori (rapid urease test and histology). Safety was determined by the adverse effects.

In this study, fifty one patients were enrolled. The eradication rate was 68.8% (31/45). Adverse effects were reported by 31.4% of the patients, and these were usually considered to be slight or moderate in the majority of the cases. Three patients had to withdraw from the treatment due to the presence of severe adverse effect. Their result indicated that the association of bismuth, furazolidone, amoxicillin and a proton-pump inhibitor is a valuable alternative for peptic ulcer patients.


'/>"/>

Contact: Lai-Fu Li
wjg@wjgnet.com
0086-105-908-0039
World Journal of Gastroenterology
Source:Eurekalert

Page: 1

Related medicine news :

1. Jenny Craig Announces Finalists for the 2008 Ideal Size Contest
2. Through-Wave Ultrasound: Effective, Economical and Ideal for Breast Imaging, Biopsy
3. The Neuropathy Associations Scientific Research Grants Focus: Autoimmune and Chemotherapy-Induced Neuropathies
4. Sale of Enzymatic Therapy, Inc. to Natures Way Holding Company Finalized
5. Ellex Announces Six-Month Results on Retina Regeneration Therapy
6. ESF workshop makes major advance in cancer radiotherapy
7. 5th Annual Global Conference on Stem Cell Therapy to be held Jan. 13-16, 2009 in NYC
8. New Study Demonstrates Cost Effectiveness of NeuroStar TMS Therapy(R) in the Treatment of Depression
9. Hormone therapy helps short children grow up
10. Therapy may block expansion of breast cancer cells
11. TomoTherapy Completes Acquisition of Linear Accelerator Manufacturer in China
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:3/24/2017)... , ... March 24, 2017 , ... “Vintage and Harvest ... retired minister and college Bible teacher residing in North Carolina with his wife, Anna ... have blessed them with six grandchildren. David is also the author of “Shadow and ...
(Date:3/24/2017)... ... ... “The Adventures of Joey, The Dog Who Barks at Puddles”: a boisterous story ... fullest, as God intended. “The Adventures of Joey, The Dog Who Barks at Puddles” ... passion for writing, especially about truth and human behavior. , Published by Christian Faith ...
(Date:3/23/2017)... ... 23, 2017 , ... A recent report from the National Council on Teacher ... NCTQ report suggests, based on a review of GPA and SAT/ACT requirements at 221 ... the U.S. It argues that this higher bar should be set by states, by ...
(Date:3/23/2017)... ... March 23, 2017 , ... Demonstrating their commitment to ... public health departments have been awarded national accreditation through the Public Health ... the expanding network of communities across the nation whose health departments meet rigorous ...
(Date:3/23/2017)... ... March 23, 2017 , ... PAINWeekEnd (PWE) Oklahoma City, on ... Avenue, will be an educational and exciting program providing busy clinicians and allied ... chronic pain. , Oklahoma is in a healthcare crisis. The state ranks 46th ...
Breaking Medicine News(10 mins):
(Date:3/23/2017)... Mosaic Life Care, based in St. Joseph, Missouri , ... network of 58 clinics, located in 22 cities, and its flagship St. Joseph Medical ... improve the delivery of health care to its patients, including the insurance, billing and ... ... Mosaic Life Care St. Joseph Medical Center ...
(Date:3/23/2017)... 2017  Transportation Insight, a multi-modal lead logistics solutions ... management firm with expertise serving clients in the food ... Zaffarano was named a 2017 Food Logistics ... the only publication exclusively dedicated to covering the movement ... "Rick has brought to Transportation Insight a wealth ...
(Date:3/23/2017)... 23, 2017 As a result of ... the prevalence of allergic diseases, cutting edge developments ... revolutionising the ways in which pharmaceutical and biotech ... promises to be both a high quality meeting ... interest groups, immunologists, research scholars and doctors. The ...
Breaking Medicine Technology: