Navigation Links
An enzyme in fish can demonstrate environmental toxins
Date:11/8/2011

The level of the enzyme carbonyl reductase (CBR) is elevated in the livers of fish that have been exposed to cleaned wastewater. Scientists at the University of Gothenburg can show that CBR has properties that may make it suitable to be used as a biomarker, an early warning signal of environmental toxins. The aim of the project is to achieve better environmental monitoring.

"While chemists measure the levels of environmental toxins, we biologists monitor their effects. We can use biomarkers to discover these effects before the levels of toxins have become fatal. The increased CBR level in fish is probably caused by chemicals in the water. This means that CBR may be a useful biomarker," says Eva Albertsson, research student in the Department of Zoology at the University of Gothenburg.

Our sewage treatment plants have been designed to remove nutrients from wastewater, but they are not very good at removing many other substances. Fish downstream of the treatment plants thus live in an environment that is filled with both toxic and non-toxic substances. Eva Albertsson's thesis presents work carried out at the Grbo treatment plant. It turned out that fish downstream of the plant had higher levels of an enzyme, CBR, in the liver than fish living upstream of the plant. Similar effects were seen also at the Bors treatment plant.

It is known that CBR in humans can protect against oxidative stress, which is a harmful reaction that the body activates in response to certain substances. Thus, the elevated levels of CBR we have seen in fish may not be harmful: they may act as protection. The elevated levels, however, may be an indication that there are substances in the cleaned wastewater that cause oxidative stress, which may in the long term develop to give harmful effects.

The substances that cause oxidative stress are present at different levels in some water, such as, for example, the water that is downstream of a sewage treatment plant. Metals, pesticides and substances that form during incomplete combustion are examples of substances that act in such a manner. Eva Albertsson has studied rainbow trout and eelpout, and shown that fish that are exposed to substances known to cause oxidative stress had higher levels of CBR. This means that the enzyme is suitable for use as a biomarker, an early warning signal, that can be used by scientists and authorities whose task is to monitor the effects of environmental toxins.


'/>"/>

Contact: Eva Albertsson
eva.albertsson@zool.gu.se
46-317-863-683
University of Gothenburg
Source:Eurekalert

Related medicine news :

1. Live-action films of worm sperm help researchers track critical fertility enzymes
2. Researchers identify enzyme that regulates degradation of damaged proteins
3. High-fat diet and lack of enzyme can lead to heart disease in mice
4. Inhibiting key enzymes kills difficult tumor cells in mice
5. Disorderly enzyme is key for antibody diversity
6. New Delhi metallo-beta-lactamase-1 enzyme acquired in Canada
7. Enzyme may drive breast cancer growth
8. Study suggests enzyme crucial to DNA replication may provide potent anti-cancer drug target
9. The TET1 enzyme steers us through fetal development and fights cancer
10. Investigators discover enzyme essential for healthy lung development
11. Newly discovered role for enzyme in neurodegenerative diseases
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:1/24/2017)... ... 2017 , ... The Cruise Web Inc. was recognized today as ... Annual MSC True Partnerships’ Awards. , The 2016 MSC True Partnerships Awards ... based on overall business growth in revenue and guests and continuous partnership support and ...
(Date:1/24/2017)... ... January 24, 2017 , ... West’s ... its annual Solutions Series of webinars will start January 31 with a session ... number of current health and benefits topics, including employee engagement, pricing transparency, population ...
(Date:1/24/2017)... (PRWEB) , ... January 24, 2017 , ... Center ... 21st century leadership, has named Hector M. Chavez, Manager, Employee & Labor Relations at ... center - as its Hispanic Leader of the Month. City of Hope is committed ...
(Date:1/24/2017)... (PRWEB) , ... January 24, 2017 , ... ... Really Need to Thrive , Well-meaning studies such as the Fordham Institute’s ... can better serve top students, such as including gifted or high-achieving students as ...
(Date:1/24/2017)... MA (PRWEB) , ... January 24, 2017 , ... American ... in Bedford, expanding access to high-quality health care for residents in the area. The ... fourth location opened during the past four years by Dave Adams and Dr. Kristina ...
Breaking Medicine News(10 mins):
(Date:1/24/2017)... Research and Markets has announced the addition of the ... - Forecast to 2025" report to their offering. ... The Global Implantable Medical ... 5.4% over the next decade to reach approximately $54.28 billion by ... is witnessing include 3D medical printing is expected to develop and ...
(Date:1/24/2017)... GAITHERSBURG, Md. , Jan. 24, 2017 /PRNewswire/ ... leader in the engineering and industrialization of biology to improve ... announced that it has entered into a definitive agreement to ... a clinical-stage company and pioneer in the development of AdenoVerse™ ... and expand upon GenVec,s expertise in adenoviral vectors and cGMP ...
(Date:1/24/2017)... 24, 2017   QR Pharma , Inc., ... novel therapies for the treatment of Alzheimer,s, Parkinson,s ... of four world-class key opinion leaders to its ... QR Pharma,s previous roster of impressive advisors in ... support the development of the breakthrough mechanism of ...
Breaking Medicine Technology: