Navigation Links
An enzyme in fish can demonstrate environmental toxins
Date:11/8/2011

The level of the enzyme carbonyl reductase (CBR) is elevated in the livers of fish that have been exposed to cleaned wastewater. Scientists at the University of Gothenburg can show that CBR has properties that may make it suitable to be used as a biomarker, an early warning signal of environmental toxins. The aim of the project is to achieve better environmental monitoring.

"While chemists measure the levels of environmental toxins, we biologists monitor their effects. We can use biomarkers to discover these effects before the levels of toxins have become fatal. The increased CBR level in fish is probably caused by chemicals in the water. This means that CBR may be a useful biomarker," says Eva Albertsson, research student in the Department of Zoology at the University of Gothenburg.

Our sewage treatment plants have been designed to remove nutrients from wastewater, but they are not very good at removing many other substances. Fish downstream of the treatment plants thus live in an environment that is filled with both toxic and non-toxic substances. Eva Albertsson's thesis presents work carried out at the Grbo treatment plant. It turned out that fish downstream of the plant had higher levels of an enzyme, CBR, in the liver than fish living upstream of the plant. Similar effects were seen also at the Bors treatment plant.

It is known that CBR in humans can protect against oxidative stress, which is a harmful reaction that the body activates in response to certain substances. Thus, the elevated levels of CBR we have seen in fish may not be harmful: they may act as protection. The elevated levels, however, may be an indication that there are substances in the cleaned wastewater that cause oxidative stress, which may in the long term develop to give harmful effects.

The substances that cause oxidative stress are present at different levels in some water, such as, for example, the water that is downstream of a sewage treatment plant. Metals, pesticides and substances that form during incomplete combustion are examples of substances that act in such a manner. Eva Albertsson has studied rainbow trout and eelpout, and shown that fish that are exposed to substances known to cause oxidative stress had higher levels of CBR. This means that the enzyme is suitable for use as a biomarker, an early warning signal, that can be used by scientists and authorities whose task is to monitor the effects of environmental toxins.


'/>"/>

Contact: Eva Albertsson
eva.albertsson@zool.gu.se
46-317-863-683
University of Gothenburg
Source:Eurekalert

Related medicine news :

1. Live-action films of worm sperm help researchers track critical fertility enzymes
2. Researchers identify enzyme that regulates degradation of damaged proteins
3. High-fat diet and lack of enzyme can lead to heart disease in mice
4. Inhibiting key enzymes kills difficult tumor cells in mice
5. Disorderly enzyme is key for antibody diversity
6. New Delhi metallo-beta-lactamase-1 enzyme acquired in Canada
7. Enzyme may drive breast cancer growth
8. Study suggests enzyme crucial to DNA replication may provide potent anti-cancer drug target
9. The TET1 enzyme steers us through fetal development and fights cancer
10. Investigators discover enzyme essential for healthy lung development
11. Newly discovered role for enzyme in neurodegenerative diseases
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:2/9/2016)... ... 2016 , ... The Journal of Pain Research has published the ... , As corresponding author Dr John F. Peppin says “Terminology matters, yet little attention ... pain patients. ‘Chronic cancer pain’ and ‘chronic non-cancer pain’ are replete in the ...
(Date:2/9/2016)... (PRWEB) , ... February 09, 2016 , ... ... therapy products, announced today the introduction of the newly designed, innovative shoulder wrap. ... and better cold therapy coverage for the injured arm and shoulder to promote ...
(Date:2/9/2016)... ... ... Shark Finds and Kevin Harrington, and the Product Managers of AsSeenOnTV.pro are pleased ... newly patented product that has solved some of the basic problems golfers have faced since ... or right after a rain shower, might understand the struggle of placing the club down ...
(Date:2/8/2016)... ... 2016 , ... Coast Dental has a new way to help parents keep ... family dentist Yvonne Dorrian, DMD, is hosting a free seminar on Friday, February 19 ... Target at 1207 North Peachtree Parkway in Peachtree City. Dr. Dorrian will have healthy ...
(Date:2/8/2016)... , ... February 08, 2016 , ... If you are ... to handle, you are not alone. According to the Center for Disease Control and ... stroke, type 2 diabetes and certain types of cancer, some of the leading causes ...
Breaking Medicine News(10 mins):
(Date:2/9/2016)... FRANCISCO , February 9, 2016 ... biotechnology company focused on developing products for Regenerative Medicine, ... be a featured presenting company at Source Capital Group,s ... on February 10-11, 2016 in New York ... on Wednesday, February 10, 2016 at 12:30 pm by ...
(Date:2/9/2016)... 9, 2016 Hearing protection devices refer to ... transmitted to the inner ear. Hearing protection devices include ... devices are recommended for users exposed to noise levels ... to HPD that are inserted in the ear canal ... to provide more natural sound perception with the help ...
(Date:2/9/2016)... -- The leader in accelerated orthodontics, OrthoAccel ® ... recipient of the 2015 Townie Choice Award in the ... device that speeds up orthodontic tooth movement by as ... with treatment, AcceleDent was selected by orthodontists from across ... survey of the most reliable and reputable products ...
Breaking Medicine Technology: