Navigation Links
An enzyme in fish can demonstrate environmental toxins
Date:11/8/2011

The level of the enzyme carbonyl reductase (CBR) is elevated in the livers of fish that have been exposed to cleaned wastewater. Scientists at the University of Gothenburg can show that CBR has properties that may make it suitable to be used as a biomarker, an early warning signal of environmental toxins. The aim of the project is to achieve better environmental monitoring.

"While chemists measure the levels of environmental toxins, we biologists monitor their effects. We can use biomarkers to discover these effects before the levels of toxins have become fatal. The increased CBR level in fish is probably caused by chemicals in the water. This means that CBR may be a useful biomarker," says Eva Albertsson, research student in the Department of Zoology at the University of Gothenburg.

Our sewage treatment plants have been designed to remove nutrients from wastewater, but they are not very good at removing many other substances. Fish downstream of the treatment plants thus live in an environment that is filled with both toxic and non-toxic substances. Eva Albertsson's thesis presents work carried out at the Grbo treatment plant. It turned out that fish downstream of the plant had higher levels of an enzyme, CBR, in the liver than fish living upstream of the plant. Similar effects were seen also at the Bors treatment plant.

It is known that CBR in humans can protect against oxidative stress, which is a harmful reaction that the body activates in response to certain substances. Thus, the elevated levels of CBR we have seen in fish may not be harmful: they may act as protection. The elevated levels, however, may be an indication that there are substances in the cleaned wastewater that cause oxidative stress, which may in the long term develop to give harmful effects.

The substances that cause oxidative stress are present at different levels in some water, such as, for example, the water that is downstream of a sewage treatment plant. Metals, pesticides and substances that form during incomplete combustion are examples of substances that act in such a manner. Eva Albertsson has studied rainbow trout and eelpout, and shown that fish that are exposed to substances known to cause oxidative stress had higher levels of CBR. This means that the enzyme is suitable for use as a biomarker, an early warning signal, that can be used by scientists and authorities whose task is to monitor the effects of environmental toxins.


'/>"/>

Contact: Eva Albertsson
eva.albertsson@zool.gu.se
46-317-863-683
University of Gothenburg
Source:Eurekalert

Related medicine news :

1. Live-action films of worm sperm help researchers track critical fertility enzymes
2. Researchers identify enzyme that regulates degradation of damaged proteins
3. High-fat diet and lack of enzyme can lead to heart disease in mice
4. Inhibiting key enzymes kills difficult tumor cells in mice
5. Disorderly enzyme is key for antibody diversity
6. New Delhi metallo-beta-lactamase-1 enzyme acquired in Canada
7. Enzyme may drive breast cancer growth
8. Study suggests enzyme crucial to DNA replication may provide potent anti-cancer drug target
9. The TET1 enzyme steers us through fetal development and fights cancer
10. Investigators discover enzyme essential for healthy lung development
11. Newly discovered role for enzyme in neurodegenerative diseases
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:6/24/2016)... ... 2016 , ... Marcy was in a crisis. Her son James, eight, was out of control. ... and physically. , “When something upset him, he couldn’t control his emotions,” remembers Marcy. ... rocks at my other children and say he was going to kill them. If ...
(Date:6/24/2016)... (PRWEB) , ... June 24, 2016 , ... Global law ... magazine’s 2016 Legal Elite. The attorneys chosen by their peers for this recognition are ... , Seven Greenberg Traurig Shareholders received special honors as members of this year’s Legal ...
(Date:6/24/2016)... ... June 24, 2016 , ... Comfort Keepers® of San Diego, ... and the Road To Recovery® program to drive cancer patients to and from their ... to ensure the highest quality of life and ongoing independence. Getting to and ...
(Date:6/24/2016)... ... June 24, 2016 , ... People across the U.S. ... magazine’s Code Talker Award, an essay contest in which patients and their families pay ... be presented at the 2016 National Society of Genetic Counselors (NSGC) Annual Education Conference ...
(Date:6/24/2016)... NY (PRWEB) , ... June 24, 2016 , ... ... Haute Living, is proud to recognize Dr. Barry M. Weintraub as a prominent ... “the most beautiful women in the world, and the most handsome men, look ...
Breaking Medicine News(10 mins):
(Date:6/23/2016)... and INDIANAPOLIS , June ... receiving a Lilly Diabetes Tomorrow,s Leaders Scholarship is any ... scholarship winners, announced today online at www.diabetesscholars.org ... type 1 diabetes stand in the way of academic ... supported the Foundation,s scholarship program since 2012, and continues ...
(Date:6/23/2016)...  Guerbet announced today that it has been named ... . One of 12 suppliers to receive ... support of Premier members through exceptional local customer service ... to lower costs. ... outstanding customer service from Premier," says Massimo Carrara ...
(Date:6/23/2016)... , June 23, 2016  Experian Health, ... and transforming the patient payment and care ... innovative new products and services that will ... revenue cycle offerings. These award-winning solutions will ... workflows, remain compliant in an ever-changing environment ...
Breaking Medicine Technology: