An enzyme in fish can demonstrate environmen... ( The level of the enzyme carbonyl red...)

An enzyme in fish can demonstrate environmental toxins

Date:11/8/2011

The level of the enzyme carbonyl reductase (CBR) is elevated in the livers of fish that have been exposed to cleaned wastewater. Scientists at the University of Gothenburg can show that CBR has properties that may make it suitable to be used as a biomarker, an early warning signal of environmental toxins. The aim of the project is to achieve better environmental monitoring.

"While chemists measure the levels of environmental toxins, we biologists monitor their effects. We can use biomarkers to discover these effects before the levels of toxins have become fatal. The increased CBR level in fish is probably caused by chemicals in the water. This means that CBR may be a useful biomarker," says Eva Albertsson, research student in the Department of Zoology at the University of Gothenburg.

Our sewage treatment plants have been designed to remove nutrients from wastewater, but they are not very good at removing many other substances. Fish downstream of the treatment plants thus live in an environment that is filled with both toxic and non-toxic substances. Eva Albertsson's thesis presents work carried out at the Grbo treatment plant. It turned out that fish downstream of the plant had higher levels of an enzyme, CBR, in the liver than fish living upstream of the plant. Similar effects were seen also at the Bors treatment plant.

It is known that CBR in humans can protect against oxidative stress, which is a harmful reaction that the body activates in response to certain substances. Thus, the elevated levels of CBR we have seen in fish may not be harmful: they may act as protection. The elevated levels, however, may be an indication that there are substances in the cleaned wastewater that cause oxidative stress, which may in the long term develop to give harmful effects.

The substances that cause oxidative stress are present at different levels in some water, such as, for example, the water that is downstream of a sewage treatment p
'/>"/>

Contact: Eva Albertsson
eva.albertsson@zool.gu.se
46-317-863-683
University of Gothenburg
Source:Eurekalert

0

GOOD

Page: 1 2
Related medicine news :

1. Live-action films of worm sperm help researchers track critical fertility enzymes
2. Researchers identify enzyme that regulates degradation of damaged proteins
3. High-fat diet and lack of enzyme can lead to heart disease in mice
4. Inhibiting key enzymes kills difficult tumor cells in mice
5. Disorderly enzyme is key for antibody diversity
6. New Delhi metallo-beta-lactamase-1 enzyme acquired in Canada
7. Enzyme may drive breast cancer growth
8. Study suggests enzyme crucial to DNA replication may provide potent anti-cancer drug target
9. The TET1 enzyme steers us through fetal development and fights cancer
10. Investigators discover enzyme essential for healthy lung development
11. Newly discovered role for enzyme in neurodegenerative diseases

Post Your Comments:

(Date:5/18/2013)... California (PRWEB) May 18, 2013 Online watch ... be Rolex watch owners at a fraction of ... of luxury timepieces in the world, buyers are urged to ... compared to buying a Rolex watch from a brick-and-mortar store, ... owned Rolex watches priced at unbelievable rates. Although some ...

(Date:5/18/2013)... Thompson HealthDay Reporter , , FRIDAY, May 17 ... the latest edition of what is considered the "bible" ... many changes continues. "This is unprecedented, the amount ... Lieberman, president-elect of the American Psychiatric Association (APA). "It,s ... it is. You have to evaluate it and then ...

(Date:5/18/2013)... (HealthDay News) -- Just a few extra cups of ... an autoimmune liver disease known as primary sclerosing cholangitis ... Mayo Clinic in Rochester, Minn., found that drinking coffee ... disease, which can lead to cirrhosis of the liver, ... not prove a cause-and-effect relationship. "While rare, ...

(Date:5/18/2013)... The use of a smartphone application significantly ... new research presented today at Digestive Disease Week ... advance of the procedure, includes dietary restrictions and ... at strict intervals. The better the preparation, the ... and precancerous polyps in the colon. The study, ...

(Date:5/18/2013)... ROCHESTER, Minn. -- Regular consumption of coffee is ... cholangitis (PSC), an autoimmune liver disease, Mayo Clinic ... the Digestive Disease Week 2013 conference in Orlando, ... of the bile ducts that results in inflammation ... of the liver, liver failure and biliary cancer. ...

Breaking Medicine News(10 mins):Health News:Time and Gems Offers Buyers the Largest Collection of Rolex Watches Yet 2 Health News:Time and Gems Offers Buyers the Largest Collection of Rolex Watches Yet 3 Health News:Latest Edition of Psychiatry's 'Bible' Launched Amid Controversy 2 Health News:Latest Edition of Psychiatry's 'Bible' Launched Amid Controversy 3 Health News:Latest Edition of Psychiatry's 'Bible' Launched Amid Controversy 4 Health News:Study Links Coffee to Lower Risk for Rare Liver Disease 2 Health News:New smartphone application improves colonoscopy preparation 2

[0] Time and Gems Offers Buyers the Largest Collection of Rolex Watches Yet [0] Latest Edition of Psychiatry's 'Bible' Launched Amid Controversy [0] Study Links Coffee to Lower Risk for Rare Liver Disease [0] New smartphone application improves colonoscopy preparation [0] Consuming coffee linked to lower risk of detrimental liver disease, Mayo Clinic finds

... - Exclusive, multi-year contract executed by Intercell and ... First sales of IXIARO under this military contract ... ICLL; OTC Bulletin Board: INRLY) announced today that ... contract with the Defense Logistics Agency (DLA), Defense ...

... Sunday, individuals all over the nation will be celebrating a ... life: their mothers. While people in the United States turn ... (IBMP) hopes to inspire some to also think of mothers ... the United States send their breast milk to infants in ...

... may be used someday against Parkinson,s, too, expert suggests, , , ... to lend a hand in the death of brain cells ... according to a newly published study. , ... normally guides molecules in and out of cells, but it ...

... and recovery fairly quick , , FRIDAY, May 8 (HealthDay News) ... from over, with hundreds of new cases being reported each day, ... issue that,s been concerning me, that has to do with a ... over," Dr. Richard Besser, acting director of the U.S. Centers for ...

... Almost Family, Inc. (Nasdaq: AFAM ), a ... that William Yarmuth, President and Chief Executive Officer, and Steve ... to present at two upcoming investor conferences. The first ... 2009 Growth Stock Conference at the Four Seasons Hotel in ...

... ANN ARBOR, Mich., May 8 Thomson Reuters on ... hospital system for significantly improving the quality and managing ... plans and Tallahassee Memorial HealthCare are overall winners of ... hospitals and healthcare payers that use data analytics to ...

Intercell Executes Multi-Year Contract for Supply of IXIARO(R) to the United States Military International Breast Milk Project Helps Mothers Worldwide Protein Might Mute Effects of Methamphetamine As Swine Flu Cases Mount, CDC Says U.S. Hasn't 'Dodged a Bullet'Almost Family to Present at Two Upcoming Conferences Thomson Reuters Honors Keystone Mercy and AmeriHealth Mercy Health Plans and Tallahassee Memorial HealthCare

(Date:5/18/2013)... , May 18, 2013 Faruqi ... firm, is investigating potential securities fraud at AVEO ... (Logo: http://photos.prnewswire.com/prnh/20120119/MM38856LOGO ) ... and its executives violated federal securities laws by ... Company,s Phase III drug trials for Tivopath (tivozanib) ...

(Date:5/17/2013)... , May 17, 2013 Orexigen® Therapeutics, Inc. (Nasdaq: ... company overview at the UBS Global Healthcare Conference in ... Wednesday, May 22 nd at 11 a.m. Eastern Time. ... the presentation, please visit the Investor Relations section of the ... be available for 14 days after the event. ...

(Date:5/17/2013)... YORK , May 17, 2013 /PRNewswire-iReach/ -- United ... Advanced Cardiac Life Support (ACLS), Pediatric Advanced Life Support ... free PALS, BLS and ACLS online course ... manuals, people simply need to build an account with ... materials for these programs, United Medical Education is setting ...

Breaking Medicine Technology:Faruqi & Faruqi, LLP Encourages Investors Who Suffered Losses In Excess Of $100,000 Investing In AVEO Pharmaceuticals, Inc. To Contact The Firm 2 ACLS Online Course Manuals are Now Available at No Cost through United Medical Education 2

[0] Faruqi & Faruqi, LLP Encourages Investors Who Suffered Losses In Excess Of $100,000 Investing In AVEO Pharmaceuticals, Inc. To Contact The Firm [0] Orexigen Therapeutics to Present at the UBS Global Healthcare Conference [0] ACLS Online Course Manuals are Now Available at No Cost through United Medical Education

... BETHESDA, Md., April 14 Micromet, Inc.,(Nasdaq: ... novel, proprietary,antibodies for the treatment of cancer, ... meeting of the American Association for,Cancer Research ... that commercial,anti-cancer antibodies trastuzumab (Herceptin(R); Genentech, Roche),cetuximab ...

... the, Tumor Suppressor P53 Inhibited Tumor Growth Synergistically in Preclinical ... ... 14 ,Peregrine Pharmaceuticals, Inc. (Nasdaq: PPHM ) announced today that ... 2008 Annual Meeting of the American Association for Cancer Research,(AACR) further ...

Cached Medicine Technology:Micromet Demonstrates That the Antibodies in Commercial Products Herceptin, Erbitux, Vectibix and Xolair Can Be Converted Into Highly Potent, T Cell- Engaging BiTE Antibodies 2 Micromet Demonstrates That the Antibodies in Commercial Products Herceptin, Erbitux, Vectibix and Xolair Can Be Converted Into Highly Potent, T Cell- Engaging BiTE Antibodies 3 Micromet Demonstrates That the Antibodies in Commercial Products Herceptin, Erbitux, Vectibix and Xolair Can Be Converted Into Highly Potent, T Cell- Engaging BiTE Antibodies 4 Micromet Demonstrates That the Antibodies in Commercial Products Herceptin, Erbitux, Vectibix and Xolair Can Be Converted Into Highly Potent, T Cell- Engaging BiTE Antibodies 5 Preclinical Study Presented at AACR Annual Meeting Shows Broad Anti-Cancer Potential of Peregrine's anti-PS Vascular Targeting Antibodies 2 Preclinical Study Presented at AACR Annual Meeting Shows Broad Anti-Cancer Potential of Peregrine's anti-PS Vascular Targeting Antibodies 3 Preclinical Study Presented at AACR Annual Meeting Shows Broad Anti-Cancer Potential of Peregrine's anti-PS Vascular Targeting Antibodies 4

Micromet Demonstrates That the Antibodies in Commercial Products Herceptin, Erbitux, Vectibix and Xolair Can Be Converted Into Highly Potent, T Cell- Engaging BiTE Antibodies Preclinical Study Presented at AACR Annual Meeting Shows Broad Anti-Cancer Potential of Peregrine's anti-PS Vascular Targeting Antibodies

Touch-Trol Pediatric Suction Catheter Mini-Tray...

SAFE-T-VAC Suction Catheter Kits with Protective Sleeve...

Our suction kits include a Tri-Flo® suction catheter, a pop-up solution basin and two sturdy, precuffed latex exam gloves in an inner wallet. Infant and pediatric kits (5/6, 8 and 10 Fr) feature ...

... kit includes a Tri-Flo® suction ... for flushing and lubrication, two ... inner wallet and a rigid ... (5/6, 8 and 10 Fr) ...

Medicine Products:

Touch-Trol Suction Pediatric Catheter Mini-Tray SAFE-T-VAC Suction Catheter Kits with Protective Sleeve AirLife™ Brand Cath-N-Glove® Suction Kits In Peel Pouch Rigid Suction Tray Kits With Saline