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Amylin Pharmaceuticals Reports First Quarter Financial Results
Date:4/21/2008

lead the call. During the call, the Company plans to review its first quarter financial results, and information regarding assumptions for the remainder of 2008 operations. For those without access to the Internet, the live call may be accessed by phone by calling (888) 536-6007 (U.S./Canada) or (706) 758-4632 (international), Conference ID# 43245695. A replay of the call will also be available by phone for 24 hours beginning approximately one hour after the close of the call and can be accessed at (800) 642-1687 (U.S./Canada) or (706) 645-9291 (international), Conference ID# 43245695.

Note Regarding Use of Non-GAAP Financial Measures

Amylin reports non-GAAP, research and development expenses, net of cost- sharing payments, which is a non-GAAP financial measure. The Company believes that investors' understanding of Amylin's net investment in research and development activities is enhanced by this disclosure. In addition, the Company refers to this non-GAAP financial information with its analysis of the Company's financial performance. This non-GAAP financial information should be considered in addition to, and not as a substitute for, or superior to, financial measures calculated in accordance with GAAP. A reconciliation of reported GAAP research and development expenses to non-GAAP research and development expenses, net of cost-sharing payments, is provided in the table that follows.

Quarter ended March 31,

2008 2007

GAAP research and development expenses $77,206 $59,564

Cost-sharing payments (17,445) (8,903)

Non-GAAP net research and development expenses,

net of cost sharing payments $59,761 $50,661

About Amylin

Amylin Pharmaceuticals is a biopharmaceutical company committed to improving lives through the
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SOURCE Amylin Pharmaceuticals, Inc.
Copyright©2008 PR Newswire.
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