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Amylin Pharmaceuticals Reports 2008 Financial Results
Date:1/27/2009

2,104 14,837 55,115 59,064 Other non-cash compensation 5,833 18,425 24,680 21,693 Depreciation and amortization 7,161 4,700 25,280 15,049 Restructuring 54,926 - 54,926 - Non-GAAP operating loss $(20,215) $(46,985) $(137,219) $(147,170)

A reconciliation of reported GAAP research and development expenses to non-GAAP research and development expenses, net of cost-sharing payments, is provided in the table that follows (in thousands, unaudited):


                              Quarter ended          Year ended
                               December 31,          December 31,
                               2008    2007         2008    2007

    GAAP research and
     development expenses    $67,022  $83,888     $293,095  $276,600
    Cost-sharing payments    (16,498) (26,248)     (70,481)  (60,261)

    Non-GAAP research and
     development expenses,
     net of cost sharing
     payments                $50,524  $57,640     $222,614  $216,339



                             AMYLIN PHARMACEUTICALS, INC.
                        CONDENSED CONSOLIDATED BALANCE SHEETS
                                   (in thousands)
                                     (unaudited)

                                                 December 31,   December 31,
                                                     2008           2007
    Assets
     Cash, cash equivalents and
      short-term investments                        $816,838     $1,130,415
     Accounts receivable, net                         62,369         73,579
     Inventories, net                                115,823        100,214
     Other current assets                             41,038         32,100
     Property, plant and equipment, net              636,922        390,301
     Other assets            
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SOURCE  Amylin Pharmaceuticals, Inc.
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