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Amylin Pharmaceuticals Reports 2007 Financial Results
Date:1/28/2008

ember 31, 2007, compared to $63.8 million for the same period in 2006.

Net loss was $76.9 million, or $0.57 per share, for the quarter ended December 31, 2007, compared to a net loss of $58.4 million, or $0.45 per share, for the same period in 2006.

Fourth quarter highlights

Highlights of Amylin's fourth quarter include the following:

-- Positive results from a 24-week study of monotherapy, or stand alone,

BYETTA in drug nave patients with type 2 diabetes. The Company plans

for a regulatory submission for a monotherapy indication to the U.S.

Food and Drug Administration, or FDA, in the first half of 2008.

-- Positive results from a 30-week comparator study of exenatide once

weekly injection and BYETTA taken twice daily in patients with type 2

diabetes. The Company anticipates a regulatory submission to the FDA by

the end of the first half of 2009.

-- Positive results from a 24-week proof-of-concept study with the

combination treatment of pramlintide, an analog of human amylin, and

metreleptin, an analog of human leptin in overweight or obese subjects,

validating the Company's novel integrated neurohormonal treatment of

obesity (INTO) strategy. The Company plans for additional clinical

development in 2008, including the initiation of a Phase 2B study.

Year ended December 31, 2007

Total revenue for the year ended December 31, 2007 was $781.0 million. This includes net product sales of $701.5 million, consisting of $636.0 million for BYETTA and $65.5 million for SYMLIN. This compares to total revenue of $510.9 million for the same period in 2006, including net product sales of $474.0 million consisting of $430.2 million for BYETTA and $43.8 million for SYMLIN.

Revenues under collaborative agreements were $79.5 million for the year ended December 31, 2007, compared to $36.8 million for the same period in 20
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SOURCE Amylin Pharmaceuticals, Inc.
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