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Amplification of a Stat5 gene produces excess oncogenic protein that drives prostate cancer spread
Date:5/7/2013

. Nevalainen. "We don't know exactly why this happens, but it is related to imperfect cell division and unstable genomes."

While it is known that excess Stat5 protein predicts early recurrence of prostate cancer, development of metastatic disease and death from prostate cancer, researchers will need to determine if Stat5 gene amplification is also linked to those outcomes, she adds.

Researchers who contributed to the study included investigators from Georgetown University, the University of Helsinki in Finland, the University of Basel in Switzerland, and the University of Tampere in Finland. The authors declare no conflicts of interest.


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Contact: Jackie Kozloski
jackie.kozloski@jefferson.edu
215-955-5296
Thomas Jefferson University
Source:Eurekalert

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