Navigation Links
Amphetamine use increases risk of aortic tears in young adults, UT Southwestern researchers report
Date:8/16/2010

DALLAS Aug. 17, 2010 Young adults who abuse amphetamines may be at greater risk of suffering a tear in the main artery leading from the heart, UT Southwestern Medical Center researchers have found.

In the study, published in the August issue of American Heart Journal, researchers examined medical records from nearly 31 million people between 18 and 49 years old hospitalized from 1995 to 2007 and found that amphetamine abuse was associated with a threefold increase in the odds of aortic dissection.

"Aortic dissection in young people is rare, but it frequently can lead to death," said Dr. Arthur Westover, assistant professor of psychiatry at UT Southwestern and the study's lead author. "Doctors should screen young adults with aortic dissection for amphetamine abuse in searching for a potential cause."

Individual case reports have suggested a link between aortic dissection and amphetamine abuse, but this is believed to be the first epidemiological study of a large group of people on the issue, Dr. Westover said.

The aorta stems from the heart and is the largest artery in the body. Dissection occurs when a tear develops in the inner layer of the aorta, allowing blood to separate, or dissect. The blood can eventually cause a rupture in the aortic wall, often resulting in death.

Amphetamines are stimulants that can be used to treat medical conditions such as attention-deficit disorder. They also are abused illegally as recreational drugs or performance enhancers. Researchers note that the abuse of amphetamines including methamphetamines, or "meth" significantly increased among hospitalized young adults from 1995 to 2007.

Amphetamines act on the body in similar ways as cocaine, which also is associated with adverse effects on the heart. Medically, amphetamines are known to increase blood pressure, and hypertension is a known trigger of aortic dissection.

Researchers also analyzed medical data for more than 49 million people 50 years or older from the same time period.

"We found that the frequency of aortic dissection is increasing in young adults but not older adults," Dr. Westover said. "It is not yet clear why."

Researchers noted that in California, Hawaii, Oregon and Washington state, the percentage of aortic dissection cases linked to amphetamine abuse among young adults during the study period was three times greater than the national figure.

"This illustrates that in areas where amphetamine abuse is more common, there are greater public health consequences," Dr. Westover said.

Dr. Westover's research previously has linked amphetamine abuse to stroke and heart attack.

"This adds to our growing understanding of the cardiovascular risks associated with abuse of amphetamines," said Dr. Paul Nakonezny, associate professor of clinical sciences and psychiatry at UT Southwestern and an author on the paper.


'/>"/>

Contact: LaKisha Ladson
lakisha.ladson@utsouthwestern.edu
214-648-3404
UT Southwestern Medical Center
Source:Eurekalert

Related medicine news :

1. Drug control efforts in Mexico reduce methamphetamine treatment admissions in Mexico and US
2. Dental school gets $1.86 million from NIH for study of methamphetamines effect on oral health
3. Researchers ID brain abnormalities in children exposed to methamphetamine in utero
4. Internet access at home increases the likelihood that adults will be in relationships
5. MicroRNA molecule increases number of blood stem cells, may help improve cancer treatment
6. Small increases in vaccine cost can cause large gaps in protection
7. Use of decision-aid program increases safety for women experiencing abuse, researchers find
8. Wood smoke exposure multiplies damage from smoking, increases risk of COPD
9. The Laser Warehouse Increases its Inventory of Used Cosmetic Lasers to Meet Growing Demand
10. Ticking biological clock increases womens libido, new research shows
11. JDR increases its 5-Year SIF and remains number one dental journal of 64 in its category
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:8/18/2017)... St. Louis, Missouri (PRWEB) , ... August 18, 2017 , ... ... ” says Suzanne Tucker, Founder of St. Louis-based positive education company Generation Mindful. To ... way they help children learn social and emotional skills, she created the Time-In Toolkit, ...
(Date:8/18/2017)... ... August 18, 2017 , ... With ... specializing in bioidentical hormone replacement therapy and integrative medicine, has become a frontrunner ... of aging, such as menopause, andropause, thyroid disorder and adrenal insufficiencies. , ...
(Date:8/18/2017)... ... 18, 2017 , ... Yisrayl Hawkins, Pastor and Overseer at The House of Yahweh in Abilene, ... on false teachings pertaining to the mother of the Savior whom the world calls “Mother ... different picture of the role of this historical woman. , “The world bows, kisses ...
(Date:8/18/2017)... ... August 18, 2017 , ... Alcovit, a lime-flavored beverage that ... its marketing efforts with its product now available through Jet.com. , After 25 ... The effervescent powdered drink is designed to quickly detox the body thereby avoiding alcohol-induced ...
(Date:8/18/2017)... CA & CARMEL, IN (PRWEB) , ... August 18, 2017 , ... ... on its 36th annual list, the most prestigious ranking of the nation's fastest-growing private ... been included in the exclusive Inc. 5000 ranking . This year’s ranking reflects ...
Breaking Medicine News(10 mins):
(Date:8/17/2017)... 17, 2017 MJAC2017 , the premier cannabis ... Media, today reveals its leading lineup. MJAC2017 ... global cannabis innovator specializing in the development of pharmaceutical and ... MassRoots, Rambridge™ and The Green Organic Dutchman are gold sponsors ... Vapes™ as silver sponsors. ...
(Date:8/17/2017)... August 17, 2017 DarioHealth Corp. (NASDAQ: ... mobile health and big data solutions, announced today ... domestic and non-U.S. investors for the sale of ... of the Company,s newly designated Series B Convertible ... Company expects to conduct a closing with respect ...
(Date:8/17/2017)... LLC Chief Science Officer, Dr. Adam Elhofy , will be discussing ... Universal Titer Boost at the 9 th annual Bioprocessing ... Bioprocessing Summit convenes more than 1,000 international bioprocess professionals to share practical ... Cell-Ess Universal ... Cell-Ess is the world,s first ...
Breaking Medicine Technology: