Navigation Links
Amgen Announces KRAS Safety Update to U.S. Prescribing Information for Vectibix(R) (Panitumumab)
Date:7/17/2009

es, avoiding unnecessary treatments in patients who are unlikely to benefit," said Sean Harper.

This label update is specific to the utility of KRAS as a biomarker for Vectibix used as a monotherapy. In the combination chemotherapy setting, the Vectibix "181" and "PRIME (203)" trials will be the first prospective Phase 3 clinical studies testing the clinical utility of KRAS as a predictive biomarker in mCRC patients in earlier lines of therapy. Data from the "181" and "PRIME (203)" trials are expected in the third quarter of 2009.

This update follows recent KRAS related action from key cancer organizations, including the American Society of Clinical Oncology (ASCO) and the National Comprehensive Cancer Network (NCCN). A Clinical Provisional Opinion (CPO) was issued by ASCO in January, where the organization recommended the use of the KRAS biomarker in selecting the appropriate patients for anti-EGFr antibody therapy. In November 2008, the NCCN announced updates to their Guidelines on Colon and Rectal Cancers. The guideline updates included the recommendation that a determination of the KRAS gene status of either the primary tumor or a site of metastasis should be part of the pre-treatment work-up for patients diagnosed with metastatic colorectal cancer.

About Colorectal Cancer

Colorectal cancer is the third most common cancer diagnosed in men and in women in the United States (U.S.). The American Cancer Society estimates that about 106,100 new cases of colon cancer and 40,870 new cases of rectal cancer will be diagnosed in 2009. Colorectal cancer is the second leading cause of cancer death among men and women in the U.S. and it has been estimated that more than 49,000 people will die from colorectal cancer in 2009. That means that one person in the U.S. dies of colorectal cancer every 9.3 minutes.

About Vectibix


'/>"/>

SOURCE Amgen
Copyright©2009 PR Newswire.
All rights reserved

Page: 1 2 3 4 5 6 7

Related medicine news :

1. Amgen Appoints Rebecca M. Henderson to the Companys Board of Directors
2. 34 Outstanding Teachers and Schools Receive $10,000 Amgen Award for Science Teaching Excellence
3. AUDIO from Medialink and Amgen: Experts Agree Infection in Cancer Patients Impacts Treatment Success
4. Amgen to Present at the Goldman Sachs Global Healthcare Conference
5. Loyola fellow receives Amgen grant to study treatments for older leukemia patients
6. Amgens Denosumab and Eli Lillys Forteo/Forsteo Will Drive Robust Annual Growth in the Osteoporosis Drug Market From 2013 to 2018
7. Amgen Highlights Data to Be Presented at ASCO
8. Amgen to Present at the Deutsche Bank 34th Annual Healthcare Conference
9. Amgen and ONSEdge Partner With Cancer Survivor Jan Ping for New Campaign
10. Amgens First Quarter 2009 Adjusted Earnings Per Share Decreased 4 Percent to $1.08
11. Amgen Announces Webcast of 2009 First Quarter Financial Results
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:7/13/2014)... Nature Genetics identifies a novel genetic and ... esophagitis (EoE), opening up potential new therapeutic strategies ... , EoE is a chronic inflammatory disorder of ... hypersensitivity to certain foods and an over-accumulation in ... (part of the body,s immune system). EoE can ...
(Date:7/13/2014)... North American water storage systems market is estimated to grow ... at a CAGR of 21.0%, from 2013 to 2018. The ... in North America. The U.S. is experiencing high growth on ... and collection, and the increased spending on modernization and upgradation ... rate in Canada, and is rising at a rapid pace ...
(Date:7/13/2014)... July 13, 2014 According to ... and Computing Market by Component (processor, GPU, DSP, ... MDA, Medical), and Geography - Forecast and Analysis ... Mobile Processing & Computing Market is expected to ... CAGR of 20.75% from 2014 to 2020. , ...
(Date:7/13/2014)... Athletes with a certain genetic make-up ... according to research presented today at the American Orthopaedic ... The research marks the first of its kind investigating ... physical events that occur after a head injury. ... in the (GT)n genotype were four times more likely ...
(Date:7/13/2014)... Fadhits.com is popular among worldwide women. Its ... beautiful. Recently, the company has announced its new selection ... more, all these outfits are available at discounted prices ... the supplier is now offering similar discounts for many ... has many other designs for sale, including flower girl ...
Breaking Medicine News(10 mins):Health News:Study finds cause of mysterious food allergy, suggests new treatment strategy 2Health News:Study finds cause of mysterious food allergy, suggests new treatment strategy 3Health News:North American Water Storage Systems Market is Expected to Reach $5,450 million by 2018 - New Report by MicroMarket Monitor 2Health News:North American Water Storage Systems Market is Expected to Reach $5,450 million by 2018 - New Report by MicroMarket Monitor 3Health News:Heterogeneous Mobile Processing & Computing Market Worth $61.70 Billion by 2020 – New Report by MarketsandMarkets 2Health News:Heterogeneous Mobile Processing & Computing Market Worth $61.70 Billion by 2020 – New Report by MarketsandMarkets 3Health News:Heterogeneous Mobile Processing & Computing Market Worth $61.70 Billion by 2020 – New Report by MarketsandMarkets 4Health News:Genetic Factors May Be Responsible for Slowing Concussion Recovery in Athletes 2Health News:Fadhits.com Announces a Special Offer on Elegant Quinceanera Dresses 2
... Gardner HealthDay Reporter , TUESDAY, Aug. 31 (HealthDay ... a strong policy statement directed toward pediatricians, parents and the ... are getting about sex from television, the Internet and other ... Media , was published online Aug. 30 and in the ...
... the National Institutes of Health and University of Chicago ... mice reduces the severity of skin and soft-tissue damage ... Staphylococcus aureus infections in the United States. By ... found they could greatly reduce the damaging effects of ...
... lawsuit about gay marriage, the talk at some point turns ... parents? Will their children whether adopted, conceived with the ... relationship adjust, adapt and succeed in a world dominated ... giving them, and come dressed in anecdotes and colored by ...
... (August 31, 2010) A new study ... Massachusetts General Hospital (MGH) suggests that S-Adenosyl Methionine ... effective, relatively well-tolerated, adjunctive treatment for adults with ... their treatment with antidepressant medication. This first-of-its-kind ...
... vaccination of healthcare personnel is a professional and ... regarding vaccination should not be tolerated, according to ... for Healthcare Epidemiology of America (SHEA). The paper, ... Healthcare Epidemiology journal and endorsed by the ...
... OAK BROOK, Ill. A study of triathletes published in ... reveals that the heart adapts to triathlon training by working ... first study using MRI to investigate effects of triathlon training ... associate professor at the University of Erlangen-Nuremberg in Erlangen, Germany. ...
Cached Medicine News:Health News:U.S. Pediatricians Decry Media's Portrayal of Sex 2Health News:U.S. Pediatricians Decry Media's Portrayal of Sex 3Health News:Treatment for S. aureus skin infection works in mouse model 2Health News:Treatment for S. aureus skin infection works in mouse model 3Health News:Children raised by gay couples show good progress through school 2Health News:Children raised by gay couples show good progress through school 3Health News:Study findings show value of dietary supplement SAMe in treatment of adults with major depressive disorders 2Health News:Study findings show value of dietary supplement SAMe in treatment of adults with major depressive disorders 3Health News:Nation's leading ID experts call for mandatory flu vaccine for all health-care personnel 2Health News:Combining resistance and endurance training best for heart health 2
(Date:7/11/2014)... , July 11, 2014 ... "Scintillator Market by Composition of Material, Application (Healthcare, ... others), End Product (Personal Instrument, Hand-Held Instruments, Fixed, ... and Analysis to 2013 - 2020", published by MarketsandMarkets, the ... CAGR of 5.62% from 2014 to 2020, and ...
(Date:7/11/2014)... -- Kindred Hospital Houston Northwest, with Wound Care Specialists, ... new outpatient wound healing center.  The wound healing ... hard to heal wounds. Chronic wounds include diabetic ... leg wounds related to blood flow issues, post-surgical ... wounds which are complex and demonstrate delayed healing. ...
(Date:7/11/2014)... On Thursday, July 10, 2014, the ... Industrial Average finished the day 0.42% lower at 16,915.07, and ... were broad based as eight out of ten sectors ended ... Index ended the day at 711.88, down 0.02%, while the ... has initiated coverage on the following equities: Covidien PLC (NYSE: ...
Breaking Medicine Technology:Scintillator Market will be worth $479.16 Million by 2020 2Scintillator Market will be worth $479.16 Million by 2020 3Scintillator Market will be worth $479.16 Million by 2020 4Kindred Hospital Houston Northwest, With Wound Care Specialists, Opens Outpatient Wound Healing And Hyperbaric Center 2Health Care Equipment Equities Movers and Shakers -- Research on Covidien, Baxter, DexCom, and Boston Scientific 2Health Care Equipment Equities Movers and Shakers -- Research on Covidien, Baxter, DexCom, and Boston Scientific 3Health Care Equipment Equities Movers and Shakers -- Research on Covidien, Baxter, DexCom, and Boston Scientific 4
... 2011 Reportlinker.com announces that a new ... catalogue: Dental Implants and ... and Market Forecasts to 2016 ... Implants and Biomaterials - Global Pipeline Analysis, ...
... 2011 Reportlinker.com announces that a new market ... Hospital Mammography Census ... the most comprehensive European market report on the ... Mammography, R&F, Angiography, CT, MRI,) and radiology IT ...
Cached Medicine Technology:Reportlinker Adds Dental Implants and Biomaterials - Global Pipeline Analysis, Opportunity Assessment and Market Forecasts to 2016 2Reportlinker Adds Dental Implants and Biomaterials - Global Pipeline Analysis, Opportunity Assessment and Market Forecasts to 2016 3Reportlinker Adds Hospital Mammography Census 2
... national reference laboratory and a worldwide leader ... offers an extensive test menu of highly ... and anatomic pathology. Owned by the University ... than half of the nation's university teaching ...
... national reference laboratory and a worldwide leader ... offers an extensive test menu of highly ... and anatomic pathology. Owned by the University ... than half of the nation's university teaching ...
... ARUP Laboratories is a national reference ... laboratory research and development. ARUP offers an ... unique medical tests in clinical and anatomic ... ARUP Laboratories' clients include more than half ...
... Laboratories is a national reference laboratory and ... and development. ARUP offers an extensive test ... tests in clinical and anatomic pathology. Owned ... clients include more than half of the ...
Medicine Products: