Navigation Links
Amgen Announces KRAS Safety Update to U.S. Prescribing Information for Vectibix(R) (Panitumumab)
Date:7/17/2009

es, avoiding unnecessary treatments in patients who are unlikely to benefit," said Sean Harper.

This label update is specific to the utility of KRAS as a biomarker for Vectibix used as a monotherapy. In the combination chemotherapy setting, the Vectibix "181" and "PRIME (203)" trials will be the first prospective Phase 3 clinical studies testing the clinical utility of KRAS as a predictive biomarker in mCRC patients in earlier lines of therapy. Data from the "181" and "PRIME (203)" trials are expected in the third quarter of 2009.

This update follows recent KRAS related action from key cancer organizations, including the American Society of Clinical Oncology (ASCO) and the National Comprehensive Cancer Network (NCCN). A Clinical Provisional Opinion (CPO) was issued by ASCO in January, where the organization recommended the use of the KRAS biomarker in selecting the appropriate patients for anti-EGFr antibody therapy. In November 2008, the NCCN announced updates to their Guidelines on Colon and Rectal Cancers. The guideline updates included the recommendation that a determination of the KRAS gene status of either the primary tumor or a site of metastasis should be part of the pre-treatment work-up for patients diagnosed with metastatic colorectal cancer.

About Colorectal Cancer

Colorectal cancer is the third most common cancer diagnosed in men and in women in the United States (U.S.). The American Cancer Society estimates that about 106,100 new cases of colon cancer and 40,870 new cases of rectal cancer will be diagnosed in 2009. Colorectal cancer is the second leading cause of cancer death among men and women in the U.S. and it has been estimated that more than 49,000 people will die from colorectal cancer in 2009. That means that one person in the U.S. dies of colorectal cancer every 9.3 minutes.

About Vectibix


'/>"/>

SOURCE Amgen
Copyright©2009 PR Newswire.
All rights reserved

Page: 1 2 3 4 5 6 7

Related medicine news :

1. Amgen Appoints Rebecca M. Henderson to the Companys Board of Directors
2. 34 Outstanding Teachers and Schools Receive $10,000 Amgen Award for Science Teaching Excellence
3. AUDIO from Medialink and Amgen: Experts Agree Infection in Cancer Patients Impacts Treatment Success
4. Amgen to Present at the Goldman Sachs Global Healthcare Conference
5. Loyola fellow receives Amgen grant to study treatments for older leukemia patients
6. Amgens Denosumab and Eli Lillys Forteo/Forsteo Will Drive Robust Annual Growth in the Osteoporosis Drug Market From 2013 to 2018
7. Amgen Highlights Data to Be Presented at ASCO
8. Amgen to Present at the Deutsche Bank 34th Annual Healthcare Conference
9. Amgen and ONSEdge Partner With Cancer Survivor Jan Ping for New Campaign
10. Amgens First Quarter 2009 Adjusted Earnings Per Share Decreased 4 Percent to $1.08
11. Amgen Announces Webcast of 2009 First Quarter Financial Results
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:8/20/2014)... August 20, 2014 With 3943.8% growth, Connexion ... of the nation’s fastest growing companies. The Inc. 500 ranks ... care sector. Connexion Point is the #1 fastest growing company ... Medicare and Medicaid, and its clients include four of the ... employs 1,000 people and has offices and contact centers in ...
(Date:8/20/2014)... a novel approach to treating cancer - using Botox. ... Science Translational Medicine shows that cancer growth ... nerves that are linked to cancer stem cells. The ... made the treatment cheap, safe and efficient. The researchers ... will soon start testing on humans. , The nervous ...
(Date:8/20/2014)... of endophthalmitis, a potentially blinding condition that can occur ... the well-known staphylococci ("staph") and streptococci ... in the August issue of Ophthalmology and ... at New York Eye and Ear Infirmary of Mount ... gram-positive bacteria, which include staph and strep infections, accounted ...
(Date:8/20/2014)... A common approach to treating kidney ... not improve survival chances for people who suddenly developed ... the University of Pittsburgh School of Medicine. ... journal PLOS One , suggest acute hemodialysis, an ... sudden kidney failure, may not provide a definitive benefit ...
(Date:8/20/2014)... UK (PRWEB) August 20, 2014 The ... to increase considerably in the offing across the top ... as of 2013 to around USD 8 billion by ... period. The growth is projected to be driven by ... which is currently lacking efficient treatment, unlike the non-squamous ...
Breaking Medicine News(10 mins):Health News:With 3943.8% Growth, Connexion Point, a Leader in Contact Centers for Health Care, Ranks 86th on the Inc. 500 List as One of the Nation’s Fastest Growing Companies 2Health News:Treating gastric cancer -- with Botox 2Health News:Researchers pinpoint most common causes of dangerous eye infection post surgery and trauma 2Health News:Researchers pinpoint most common causes of dangerous eye infection post surgery and trauma 3Health News:Pitt Analysis Questions Use of Acute Hemodialysis Treatment 2Health News:Top 8 Developed Nations NSCLC Market to Grow at CAGR of 6.6% Through 2020, Says GBI Research in Its Report Published at MarketPublishers.com 2Health News:Top 8 Developed Nations NSCLC Market to Grow at CAGR of 6.6% Through 2020, Says GBI Research in Its Report Published at MarketPublishers.com 3Health News:Top 8 Developed Nations NSCLC Market to Grow at CAGR of 6.6% Through 2020, Says GBI Research in Its Report Published at MarketPublishers.com 4
... kill cervical cancer cells missed by chemotherapy , , TUESDAY, ... Avastin to radiation and chemotherapy improves results for patients ... mifepristone (RU-486, the so-called abortion pill) to chemotherapy kills ... are the conclusions of two reports on new trends ...
... OrthoSynetics(TM), the largest,provider of business services to orthodontic ... by hiring four new team members with,extensive experience ... year, we have bolstered our leadership team and,infrastructure ... said Chris Roussos, president and CEO of OrthoSynetics. ...
... Primary Less Than One Week Away, AARP Members,Gather ... They Debate,In Philadelphia., PHILADELPHIA, April 15 ... primary vote, the nation will be,watching Sen. Barack ... for,the Democratic Party,s presidential nomination during a debate ...
... Va., April 15 The American,Chemistry Council (ACC) ... Toxicology Program,s (NTP) Center for the Evaluation of,Risks ... last year,yesterday,s release of the draft NTP Brief ... or high level concerns for adverse effects of,bisphenol ...
... colon cancer, premature aging poses worries for manned missions ... -- Astronauts may be at increased risk of colon ... in space, a new report says. , The study, ... for Cancer Research annual meeting in San Diego, has ...
... tumors may be a factor, experts suggest, , , TUESDAY, ... of breast cancer dropped dramatically after millions of American ... doesn,t seem to have benefited black women. ... stayed essentially the same for black women from 2002 ...
Cached Medicine News:Health News:Extra Drug Improves Rectal Cancer Treatment 2Health News:Extra Drug Improves Rectal Cancer Treatment 3Health News:OrthoSynetics(TM) Expands Sales Team; Prepares to Grow 2Health News:AARP to Host Discussion and Debate Watch Event 2Health News:AARP to Host Discussion and Debate Watch Event 3Health News:Draft National Toxicology Program Report Supports Safety of Bisphenol A 2Health News: Space Radiation a Risk for Astronauts 2Health News:Breast Cancer Unchanged in Black Women, Despite Drop in HRT Use 2Health News:Breast Cancer Unchanged in Black Women, Despite Drop in HRT Use 3
(Date:8/20/2014)... 20, 2014 Reportlinker.com announces that ... in its catalogue: Personal Accident ... and Opportunities to 2017 ... The report provides in depth market analysis, ... accident and health insurance segment, including: • ...
(Date:8/20/2014)... , Aug. 20, 2014 The National Necrotizing ... Fernando Davila has been successfully treated for a life ... Dr, Anibal R. Gauto , Medical Director of Inpatient ... Eisenhower Medical Center in Rancho Mirage, California ... pioneered by Dr. John Crew at Seton Hospital ...
(Date:8/20/2014)... 20, 2014   Ventana Medical Systems, Inc. ... announced that its VENTANA System for Primary Diagnosis ... European Union for routine pathology, including primary diagnosis ... VENTANA Virtuoso software coupled with either the VENTANA ... scanner, provides automated digital slide creation, case management ...
Breaking Medicine Technology:Personal Accident and Health Insurance in Canada, Key Trends and Opportunities to 2017 2Personal Accident and Health Insurance in Canada, Key Trends and Opportunities to 2017 3Personal Accident and Health Insurance in Canada, Key Trends and Opportunities to 2017 4Personal Accident and Health Insurance in Canada, Key Trends and Opportunities to 2017 5Personal Accident and Health Insurance in Canada, Key Trends and Opportunities to 2017 6Personal Accident and Health Insurance in Canada, Key Trends and Opportunities to 2017 7Personal Accident and Health Insurance in Canada, Key Trends and Opportunities to 2017 8Personal Accident and Health Insurance in Canada, Key Trends and Opportunities to 2017 9Personal Accident and Health Insurance in Canada, Key Trends and Opportunities to 2017 10Personal Accident and Health Insurance in Canada, Key Trends and Opportunities to 2017 11Personal Accident and Health Insurance in Canada, Key Trends and Opportunities to 2017 12Personal Accident and Health Insurance in Canada, Key Trends and Opportunities to 2017 13Personal Accident and Health Insurance in Canada, Key Trends and Opportunities to 2017 14Personal Accident and Health Insurance in Canada, Key Trends and Opportunities to 2017 15Personal Accident and Health Insurance in Canada, Key Trends and Opportunities to 2017 16Personal Accident and Health Insurance in Canada, Key Trends and Opportunities to 2017 17Personal Accident and Health Insurance in Canada, Key Trends and Opportunities to 2017 18Personal Accident and Health Insurance in Canada, Key Trends and Opportunities to 2017 19Personal Accident and Health Insurance in Canada, Key Trends and Opportunities to 2017 20Personal Accident and Health Insurance in Canada, Key Trends and Opportunities to 2017 21Personal Accident and Health Insurance in Canada, Key Trends and Opportunities to 2017 22Personal Accident and Health Insurance in Canada, Key Trends and Opportunities to 2017 23Rancho Mirage, California Physician Saves Casino Worker from Deadly 'Flesh Eating Disease' 2Rancho Mirage, California Physician Saves Casino Worker from Deadly 'Flesh Eating Disease' 3Rancho Mirage, California Physician Saves Casino Worker from Deadly 'Flesh Eating Disease' 4Rancho Mirage, California Physician Saves Casino Worker from Deadly 'Flesh Eating Disease' 5Rancho Mirage, California Physician Saves Casino Worker from Deadly 'Flesh Eating Disease' 6Full digitization of the anatomic pathology lab is here with the VENTANA System for Primary Diagnosis 2Full digitization of the anatomic pathology lab is here with the VENTANA System for Primary Diagnosis 3
... Md., July 26, 2011 Vapotherm announced today ... device developed specifically for homecare and other low ... the U.S. and European markets. ... patients in home and other extended care environments. ...
... July 26, 2011 Patients at Resurrection Medical Center (RMC), ... now receive non-invasive, whole-body PET/CT scans in just minutes. The ... in the world, the new 128-slice PET/CT scanner is a ... imaging techniques within a single machine. The ...
Cached Medicine Technology:Vapotherm Announces Commercial Launch of Flowrest® Homecare Device 2Resurrection Medical Center First in Chicago - 8th in the World - to Offer 128-Slice PET/CT Scanner Technology 2
... drying system, 220-240 V, includes Model 583 gel ... 583 gel dryer is a vacuum-based gel dryer ... cm with variable temperature control and three preprogrammed ... vacuum pump used for pulling vacuum on gel ...
... system utilizes a hot air drying device for ... to four drying frames at once. Gels are ... viewing. The assembly table is recessed to provide ... frame. This 230 V, 50 Hz system includes ...
The GelAir™ dryer is a component of the GelAir drying system. Supplied as a 115 V, 60 Hz gel drying oven....
... voltage power supply, the 105 is very simple ... switch control the output, which is variable in ... two-position switch toggles the bright LED display from ... is equipped with an over current detector for ...
Medicine Products: