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American Society of Clinical Oncology issues annual report on progress against cancer
Date:12/5/2011

ALEXANDRIA, Va. The American Society of Clinical Oncology (ASCO) today released Clinical Cancer Advances 2011: ASCO's Annual Report on Progress Against Cancer, an independent review of the advances in cancer research that have had the greatest impact on patient care this year. The report also identifies the most promising trends in oncology and provides insights from experts on where the future of cancer care is heading.

"We've made significant strides in clinical cancer research over the past year and this report adds renewed hope for patients," said Nicholas J. Vogelzang, MD, Co-Executive Editor of the report. "More personalized treatment approaches and advances in early detection are helping patients live longer, healthier lives. But we must improve the nation's clinical research system and expand access to quality cancer care to accelerate the pace of progress."

This year's top research advances demonstrate new therapies for reducing cancer recurrence, progress made against hard-to-treat cancers, and improvements in cancer prevention and screening. The report also highlights several new drug approvals that bring smarter, more effective therapies to specific genetic subgroups of patients with cancer. The top five advances selected by the editors are:

  • A Phase III study finding that vemurafenib (Zelboraf), which targets a common mutation in melanoma in a gene called BRAF, improved overall survival in patients with advanced melanoma when compared to standard chemotherapy

  • A large national screening trial of more than 50,000 current and former heavy smokers that found three annual low-dose computed tomography (CT) scans reduced the death rate from lung cancer by 20 percent compared to those who were screened with three annual chest X-rays

  • FDA approvals on therapies for two hard-to-treat cancers:
    1. Crizotinib (Xalkori) was approved for patients with advanced non-small-cell lung cancer who harb
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Contact: Susie Tappouni
susie.tappouni@asco.org
571-483-1355
American Society of Clinical Oncology
Source:Eurekalert

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