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American Heart Association 2008 Wrap-Up Report: Top Research Advances Include Studies That Influence Medical Care, Apply Science To 'Real World' Communities
Date:1/21/2009

roke and the GWTG: Coronary Artery Disease (CAD) modules of GWTG, demonstrate that participation in hospital-based quality improvement programs such as GWTG is associated with substantially improved hospital performance.

Source: 1) Archives of Internal Medicine, Feb. 25, 2008; Arch Intern Med 2008; 168:411-17; 2) Archives of Internal Medicine, Sept. 8, 2008; Arch Intern Med 2008; 168:1813-19; www.jama.ama-assn.org.

Funding: 1) Supported in part by an unrestricted educational grant to the American Heart Association by Pfizer Inc. 2) Funded in part by a grant from the National Center for Research Resources (NCRR), a component of the National Institutes of Health (NIH); GWTG-CAD is supported by an unrestricted educational grant from Merck-Schering-Plough Pharmaceutical; data analysis was funded by a grant from the American Heart Association.

3. Type 2 diabetes: What is the legacy of intensive treatment?

10-year follow-up of intensive glucose control in type 2 diabetes; Long-term follow-up after tight control of blood pressure in type 2 diabetes

The UKPDS (UK Prospective Diabetes Study) has now followed patients with type 2 diabetes for 10 years after the initial period in which the benefits of HbA1c control by drug treatment were established. In 2008, follow-up data demonstrated that, while the improvement in HbA1c levels was lost after the first several years, the reduction in diabetes-related endpoints and microvascular disease continued, and over time, a significant reduction in heart attacks and deaths from any cause emerged. This reinforces the benefit of good diabetes control in type 2 diabetes, adding importantly to the benefits demonstrated by the earlier Diabetes Control and Complications Trial. In contrast, in another section of the study,
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