Navigation Links
American Diabetes Association's preferred testing method fails to identify kids with diabetes
Date:11/21/2011

In 2009, the American Diabetes Association (ADA) recommended that Hemoglobin A1c be exclusively used for the diagnosis of diabetes in children. The simple test measures longer-term blood sugar levels -- without requiring patients to fast overnight. However, a new U-M study has shown that these tests are not very accurate in children.

"We found that Hemoglobin A1c is not as reliable a test for identifying children with diabetes or children at high risk for diabetes compared with other tests in children," says Joyce M. Lee, M.D., M.P.H., lead author of the study and a pediatric endocrinologist at U-M's C.S. Mott Children's Hospital. "In fact, it failed to diagnose two out of three children participating in the study who truly did have diabetes."

Although tests that require patients to fast are the most accurate tests, they are difficult to obtain in clinical practice, highlighting the need for improved nonfasting testing strategies.

Due in part to high rates of childhood obesity, the Centers for Disease Control estimates that approximately 2.5 million children in the U.S. currently qualify for diabetes screening.

The study, published online ahead of print in the journal Diabetes Care, tested 254 overweight children using both fasting and non-fasting methods. Researchers found that the recommended test, Hemoglobin A1c, missed more cases of pre-diabetes or diabetes compared to other tests.

Participants in the study were defined as having prediabetes or diabetes based on a gold standard test. They were first tested using the Hemoglobin A1C test. After fasting for 12 hours, they returned on a separate day and were tested using a fasting method.

Based on the results, researchers urge that a nonfasting one-hour glucose challenge test, or a random glucose, may be promising methods for identifying children with prediabetes or diabetes.

"Other pediatric organizations, like the American Academy of Pediatrics, have not endorsed the use of HbA1c yet. However, there is concern that should they endorse it, more and more providers would use these testing methods, leading to an increase in missed diagnoses in the pediatric population," says Lee.

Researchers intend to use their data to drive future recommendations about screening for diabetes.

"We are currently studying whether the promising nonfasting tests, including the 1-hour glucose challenge test or the random glucose, could be used in combination with clinical characteristics to better identify which children have prediabetes or diabetes," says Lee.


'/>"/>

Contact: Lauren McLeod
lemcleod@med.umich.edu
734-764-2220
University of Michigan Health System
Source:Eurekalert

Related medicine news :

1. More Americans Living to 90, U.S. Census Finds
2. Poorer Americans See Sharper Health Declines With Age
3. Leading North American institutions endorse the Berlin Declaration on Open Access to Knowledge
4. Community leaders honored for helping Americans most in need
5. Older Americans Encouraged to Get Fit
6. Scott & White Healthcare and American Cancer Society enter into partnership for prevention study
7. Gene variant increases risk of kidney disease in African-Americans
8. More African-Americans burdened by osteoarthritis in multiple large joints
9. Foreclosure Crisis Threatening Americans Health: Study
10. African-American women with gestational diabetes face high long-term diabetes risk
11. African-Americans more likely to donate kidney to family member
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:3/28/2017)... ... 28, 2017 , ... Columbus OH. Dr. Justin Harper, Founder of Juvly Aesthetics ... in the country to sit on the 2017 National Advisory Board for Allergan’s Facial ... Dr. Harper helped propel the clinic from a small start-up to number 78 in ...
(Date:3/28/2017)... ... March 28, 2017 , ... AutismOne announced the Board ... of Integrative Medicine and available for application on Saturday, May 27, 2017, following ... in Colorado Springs. , Ed Arranga, president of AutismOne, stated: "Many of the ...
(Date:3/28/2017)... Square, PA (PRWEB) , ... March 28, 2017 , ... ... online and across a variety of business channels. , While many results are ... of any public relations program. , When it comes to measurement, firms should ...
(Date:3/28/2017)... Perry, GA (PRWEB) , ... March 28, 2017 , ... ... headquarters to Marshallville, Georgia, in early March. , The seed processing plant opened in ... the location since 2016. The new office allows opportunity for transition of Patten Seed ...
(Date:3/28/2017)... NY (PRWEB) , ... March 28, 2017 , ... Oily skin is a common and ... Advanced Dermatology has a lot to offer to the discussion of dealing with ... news is that there are many home remedies that can help remove the oily shine ...
Breaking Medicine News(10 mins):
(Date:3/27/2017)... Md. , March 27, 2017  ImMAGE Biotherapeutics ... its immunotherapy successfully passed early toxicology and efficacy studies. ... system to target a specific protein, MAGE A, in ... negative breast cancer. After 4 weeks ... able to show very little toxicity in a full ...
(Date:3/27/2017)... STUTTGART, Germany , March 27, 2017 /PRNewswire/ ... provide over 7,000 attendees and more than 600 ... learn, and discover opportunities and solutions that will ... - 6 April 2017 at the Messe Stuttgart, ... is the preeminent medical technology platform showcasing the ...
(Date:3/27/2017)... CHICAGO , March 27, 2017  A ... Educators (AADE) found that Medicare,s Competitive Bidding Program (CBP) ... diabetes testing supplies. The lack of choice forces beneficiaries ... can have dire health consequences. AADE,s ... reports by AADE and others pointing out the inherent ...
Breaking Medicine Technology: