Navigation Links
American College of Cardiology/American Heart Association Comment on the FDA Public Health Advisory Regarding a Drug Interaction Between Clopidogrel and Omeprazole
Date:11/17/2009

ORLANDO, Fla., Nov. 17 /PRNewswire-USNewswire/ -- Today the FDA notified healthcare professionals of new safety information concerning a drug interaction between clopidogrel, an anti-clotting medication, and omeprazole, a proton pump inhibitor (PPI) used to reduce stomach acid.

The FDA notes that they have new data showing that when healthy volunteers received clopidogrel with omeprazole, clopidogrel was less effective in its anti-clotting action than when given without omeprazole. The data are not yet peer-reviewed and published; however the FDA recommends that patients who are using clopidogrel should consult with their healthcare provider if they are currently taking or considering taking omeprazole, including Prilosec OTC.

Clopidogrel is often prescribed to people who have chest pain, have had a heart attack or undergone an artery-opening procedure such as angioplasty or stenting. Effective anti-clotting therapy is proven to reduce the risk of another heart event.

Since clopidogrel can cause bleeding in the stomach, medications like omeprazole may be used in combination to reduce stomach acid and prevent stomach bleeding. Omeprazole is available both by prescription and as an over-the-counter preparation (Prilosec OTC) used to treat frequent heartburn.

The FDA public health advisory lists other medications including antacids and medicines that reduce stomach acid (ranitidine, famotidine, nizatidine) that do not interfere with the anti-clotting activity of clopidogrel, but they suggest that cimetidine should not be used.

The FDA's statement is not based on any new published, peer-reviewed clinical trials showing changes in cardiovascular outcomes.

Visit http://www.fda.gov/Drugs/DrugSafety/PublicHealthAdvisories/ucm110594.htm for the full FDA announcement.

The American Heart Association receives funding primarily from individuals; foundations and corporations (including pharmaceutical, device manufacturers and other companies) that also make donations and fund specific association programs and events. The association has strict policies to prevent these relationships from influencing science content. Revenues from pharmaceutical and device corporations are available at www.americanheart.org/corporatefunding.

SOURCE American Heart Association; American College of Cardiology


'/>"/>
SOURCE American Heart Association; American College of Cardiology
Copyright©2009 PR Newswire.
All rights reserved

Related medicine news :

1. Highlights of NHLBI-supported research presented at American Heart Associations Scientific Sessions
2. Mississippi Baptist Medical Center Receives American College of Cardiology Foundation's NCDR ACTION Registry-GWTGTM Gold Performance Achievement Award
3. The ZigBee Alliance and the American Telemedicine Association to Collaborate on Advancing Use of Telehealth Solutions
4. United American Healthcare Corporation Announces Fiscal 2010 First Quarter Results
5. American Heart Association Late Breaking Clinical Trial Report: In Patients on Statins, Raising Good Cholesterol with Niacin, but not Reducing Bad Cholesterol with Ezetimibe, Decreases Plaque Build-Up
6. American Heart Associations Scientific Sessions Media Alert
7. American Heart Association Late Breaking Clinical Trial Report: Tests Predict Which Patients Are Resistant to Anti-Clotting Therapy During Angioplasty, Stenting
8. LTC Awareness Month Finds Americans Still in Dark about Long-Term Care
9. New Poll Finds 71 Percent of Americans Favor Investing More in Disease Prevention as Central to Health Reform
10. Regence Recognized as an American Heart Association Start! Fit-Friendly Company
11. African-Americans with colorectal cancer have poorer outcomes, lower survival rates
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:1/20/2017)... raton florida (PRWEB) , ... January 20, 2017 , ... ... at the Dana Farber Cancer Institute. For Betsy, the clinical trial has been ... her cancer has not worsened. , Betsy Brauser was diagnosed with ovarian cancer ...
(Date:1/20/2017)... ... January 20, 2017 , ... “Code Word: Chocolate Biscuit”: a biographical account following a man ... is the creation of published author, Marlyn Ivey, born in Lynn Haven, Florida and at ... school and at 19 years of age, he joined the Navy and got married right ...
(Date:1/20/2017)... , ... January 20, 2017 , ... “Knowledge is God’s ... guided by faith. “Knowledge is God’s Lighthouse” is the creation of published author, Gene ... novels, and poetry collections. , “I have been writing since high school and ...
(Date:1/19/2017)... , ... January 19, 2017 , ... Next week after ... be repealed by Congressional political games that circumvent health needs of over 30 million. ... capture the human anxieties and needs government public servants were suppose to prioritize. Interviews ...
(Date:1/19/2017)... ... January 19, 2017 , ... WhoHaha , a digital media company ... Heart Association (AHA) to produce a three-part video series that uses humor to highlight ... of the launch of AHA’s Healthy For Good™ movement, which is designed to inspire ...
Breaking Medicine News(10 mins):
(Date:1/19/2017)... Jan. 19, 2017 Report Details ... Which areas are going to grow at the fastest ... 2026, assessing data, trends, opportunities and prospects. Our ... the most lucrative areas in the industry and the ... forecasted sales across the all the major categories of ...
(Date:1/19/2017)... , Jan. 19, 2017 Conference Call and Webcast to ... ) today announced it will release results for the fourth quarter ... ... host a conference call at 4:30 PM ET on Wednesday, February ... full year 2016 financial results and other corporate activities. To participate ...
(Date:1/19/2017)... Jan. 19, 2017 Many patients don,t realize ... medication when a pharmacy just a few blocks away ... alleviate this problem Medicationdiscountcard.com has created a ... exactly how much their medication will cost at most ... Medicationdiscountcard.com takes all ...
Breaking Medicine Technology: