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ARTICLE #5 EMBARGOED FOR 9 A.M., EASTERN TIME, Sept. 10, 2007

Lung on a chip and other marvels from microfluidic devices
Chemical & Engineering News

Tiny new laboratory tools termed microfluidic devices are helping biomedical researchers to better understand the physiological and chemical processes underlying high blood pressure, stroke, sickle cell disease and other disorders, according to an article scheduled for the Sept.10 issue [http://pubs.acs.org/cen/coverstory/85/8537cover.html] of Chemical & Engineering News, ACS weekly newsmagazine.

Among the exciting developments described in the article is a lung on a chip device that will give researchers new insights into fluid dynamics in the diseased lung a key to new treatments for pneumonia, cystic fibrosis and asthma.

In the C&EN cover story, senior editor Celia Henry Arnaud describes how microfluidic devices, which include such features as micrometer-scale channels and wells as part of sophisticated lab-on-a-chip instruments, provide unprecedented biological realism needed to shed light on todays most challenging medical problems. The devices enable scientists to study the kinds of fluid movements and chemical interactions that occur in cells, tissues, and even organs in ways that arent possible with test tubes and Petri dishes, Arnaud notes.

ARTICLE #5 EMBARGOED FOR 9 A.M., EASTERN TIME, Sept. 10, 2007
Mimicking biological systems: Microscale control of the chemistry and physics of cellular microenvironments reveals new biology

This story will be available on Sept. 10 at http://pubs.acs.org/cen/coverstory/85/8537cover.html

FOR ADVANCE INFORMATION, CONTACT:
Michael Bernstein
ACS News Service
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