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American Chemical Society's Weekly PessPac -- Feb. 18, 2009
Date:2/23/2009

of Response to Isoliquiritigenin in Brains of Acute Cocaine Treated Rats"

DOWNLOAD FULL TEXT ARTICLE: http://pubs.acs.org/stoken/presspac/presspac/full/10.1021/pr800237s

CONTACT:
Meeyul Hwang, Ph.D.
The Research Center for Biomedical Resource of Oriental medicine
Daegu Haany University
Daegu, South Korea
Phone: 82-53-770-2296
Fax: 82-53-770-2335
Email: meeyul@hanmail.net


ARTICLE #4 FOR IMMEDIATE RELEASE

Soybean product fights abnormal protein involved in Alzheimer's disease
Journal of Agricultural and Food Chemistry

A vegan food renowned in Asia for its ability to protect against heart attacks also shows a powerful ability in lab experiments to prevent formation of the clumps of tangled protein involved in Alzheimer's disease, scientists in Taiwan are reporting. Their study is in the Feb. 11 issue of ACS' Journal of Agricultural and Food Chemistry, a bi-weekly publication.

Rita P. Y. Chen and colleagues point out that people in Asia have been eating natto a fermented food made from boiled soybeans for more than 1,000 years. Natto contains an enzyme, nattokinase, that has effects similar to clot-busting drugs used in heart disease.Nattokinase is sold a dietary supplement to improve the body's circulatory system. The scientists term this the first study on whether nattokinase also can dissolve amyloids. Those tangled proteins are involved in Alzheimer's disease and several other health problems.

In the study, the nattokinase degraded several kinds of amyloid fibrils, suggesting its possible use in the treatment of amyloid-related diseases. "Moreover, since natto has been ingested by humans for a long time, it would be worthwhile to carry out an epidemiological study on the rate of occurrence of various a
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Contact: Michael Woods
m_woods@acs.org
202-872-6293
American Chemical Society
Source:Eurekalert  

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