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American Cancer Society awards new research and training grants
Date:4/8/2013

bined with endocrine therapies to create more broadly effective treatments for this most common breast cancer.

Zhongsheng You, PhD, of Washington University School of Medicine is studying a type of DNA mutation called a double-strand break that can lead to cancer. Most human cancers are caused by DNA mutations, but the body's cells normally repair themselves when breaks occur. When this self-repair doesn't happen, cancer can develop. Dr. You seeks to understand the processes by which the body monitors DNA mutations and repairs them. A fundamental understanding of these processes is vital to development of effective treatments.

Robert Gramling, MD, DSc, of the University of Rochester is directing his research at two key missions of the American Cancer Society to advance the science of palliative care and to ameliorate health disparities. Dr. Gramling is exploring how health care providers communicate with patients and family about prognosis in advanced cancer and how racial and ethnic culture affects communication. Effective communication is essential for crafting individual treatment plans that honor patient preferences and goals in their cultural context.

Jinping Xu, MD, of Wayne State University is conducting psychosocial research to learn why 90% of men with low-risk prostate cancer detected by prostate-specific antigen screening choose immediate, aggressive treatment instead of active surveillance. Surgery and radiation treatment can cause diminished sexual function and urinary incontinence while active surveillance involves monitoring the cancer and treating only if it progresses. Dr. Xu's two-year study of white and black men with newly diagnosed low-risk prostate cancer will elucidate how and why men choose a specific treatment and what role race or geographical location play in treatment choice.

Egbert Grinage, MD, of Yale University is the 2013 recipient of the American Cancer Society Audrey Meyer Mars International Fell
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Contact: David Sampson
david.sampson@cancer.org
American Cancer Society
Source:Eurekalert

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