The American Cancer Society, the largest non-government, not-for-profit funding source of cancer research in the United States, has awarded 94 new national research and training grants totaling $45,097,000 to 61 institutions nationwide in the second of two grants cycles for 2009. The grants go into effect beginning January 1, 2010.
For more than 60 years, the American Cancer Society has funded research and training of health professionals to investigate the causes, prevention, and early detection of cancer, as well as new treatments, cancer survivorship, and end of life support for patients and their families. Since its founding in 1946, the American Cancer Society's extramural research grants program has devoted about $3.4 billion to cancer research and has funded 42 researchers who have gone on to win the Nobel Prize. Below are highlights of new grants.
Julian Sage, PhD, Stanford University has developed a mouse model of small cell lung cancer that may allow him to identify lung cancer stem cells. Those cells could provide an important platform for the development of more effective techniques for early detection and new treatments.
Curtis Schneider, PhD, California Institute of Technology, working with Dr. Jackie Barton, will investigate whether the recently identified loss of DNA repair pathways in tumor cells can be exploited for both therapy and for diagnostics, and has devised a strategy to develop compounds that could mark cells in the colon before they progress to cancer.
Titia de Lange, PhD, Rockefeller University, a new ACS Research Professor, is studying the role of telomeres in cancer. Telomeres are the protective caps on the end of chromosomes that limit how many times the cell can divide. Unlike normal cells, cancer cells develop ways to maintain the length and function of telomeres so they survive no matter how many times they divide.
Nicole Neel, PhD, Lineberger Comprehe
|Contact: David Sampson|
American Cancer Society