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American Cancer Society awards 152 new research and training grants
Date:5/17/2010

he disease, and provide the basis for the development of new treatment options.

  • Dr. Mikhail Kolinin of the University of Texas Health Sciences Center in Houston is studying the association of obesity and cancer. In his studies, he is investigating how adipose tissue might promote tumor growth, perhaps providing avenues for new drug development or even to prevent cancer progression.

  • Kimberley Evason, PhD, at the University of California at San Francisco is seeking to better understand the mechanisms involved in Hepatic Stellate Cells (HSC) development, and learn more precisely how these cells affect the behavior of liver cancer. These studies will improve the understanding of how liver cancer is initiated, grows, and metastasizes and in the long term may suggest ways in which HSCs could be targeted in humans to prevent or treat liver cancer.

  • Sharon DeMorrow, PhD at Texas A&M University will test the idea that serotonin and dopamine help bile duct cancer cells migrate and invade other tissues, in hopes of identifying targets for the development of new treatment options for this devastating cancer.

  • Dr. Emmanuel Skordalakes at the Wistar Institute is studying the role of telomerase in maintaining telomere length and thus preventing cell senescence. Determining the structure of telomerase will allow the design of therapies to inactivate this enzyme in cancers and prevent the immortalization that tumor cells have developed.

    Cancer Prevention

    • Jane McElroy, PhD of the University of Missouri, Columbia is studying the risk of endometrial cancer as it relates to cadmium body burden levels, as measured by the amount of cadmium in urine. Her study seeks to investigate cadmium exposure and endometrial cancer risk in a population-based case-control study.

    • Dorothy Apollonio, PhD, at the University of California at San Francisco is investigating how emerging research can be translated
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    Contact: David Sampson
    david.sampson@cancer.org
    American Cancer Society
    Source:Eurekalert

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