Navigation Links
American Academy of Dermatology Issues New Guidelines For the Management of Psoriasis With Systemic Medications
Date:6/4/2009

ial to minimize the toxicity of any therapy. For example, the most common and generally minor side effects of methotrexate that most often occur at the time it is administered include nausea, fatigue, inflammation of the mucous membranes of the mouth and anorexia. The most serious toxicities associated with methotrexate are white blood cell and platelet deficiency, liver damage and lung scarring.

Since methotrexate can cause birth defects or terminate a pregnancy, it is not prescribed to women attempting to conceive. In addition, methotrexate should not be prescribed to nursing mothers, those with chronic liver disease, alcoholics, or patients with immunodeficiency syndromes, among others.

Cyclosporine

Cyclosporine is one of the most effective treatments for psoriasis and induces immunosuppresion by inhibiting the first phase of T-cell activation. When the medication is used long-term (i.e., three to five years), a significant number of patients will develop some degree of glomerulosclerosis, scarring of the kidney's blood vessels. For this reason, Dr. Pariser noted that published guidelines in the United States limit the use of cyclosporine to one year.

Efficacy & Dosage

Numerous clinical trials have demonstrated the efficacy of cyclosporine used as a short-term treatment for psoriasis, with minimal toxicities in healthy patients. Specifically, studies show at 3 mg/kg and 5 mg/kg per day, 36 percent and 65 percent of patients, respectively, achieved a clear or almost clear result after eight weeks. In addition, after eight to 16 weeks, 50 to 70 percent of patients achieved a 75 percent or greater improvement in their PASI score. Cyclosporine is generally prescribed to adult, non-immunocompromised patients with severe psoriasis who have not responded to at least one systemic therapy or in patients who cannot tolerate other systemic medications.

Generally,
'/>"/>

SOURCE American Academy of Dermatology
Copyright©2009 PR Newswire.
All rights reserved

Page: 1 2 3 4 5 6

Related medicine news :

1. Many Older Americans Have Active Sex Lives
2. Despite grumbling, most Americans say they are happy at work
3. Record Number of Americans Lack Health Insurance
4. Longaberger Expands Horizon of Hope Campaign to Build Support for American Cancer Societys Breast Cancer Initiatives
5. AUDIO from Medialink and Pfizer: Number of Uninsured Americans Grows to 47 Million
6. New Survey Shows Americans are Still Concerned About Food Safety, Yet Still Not Smart About What They Like to Eat
7. Novo Nordisk Appoints New Leader of North American Business
8. Amid Improving Life Expectancy Rates, Risk of Premature Death is Still Significant for Americans, New Study Shows
9. Primary biliary cirrhosis more severe in African-American and Hispanic patients
10. AOA President Calls on Congress to Reauthorize SCHIP and Take Action to Ensure Health Care Coverage for All Americans
11. American Chemical Societys Weekly Presspac -- Sept. 5, 2007
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:12/15/2014)... December 15, 2014 Cancer researchers have ... underlying genetic causes of deadly malignant pleural mesothelioma. Surviving ... on their website. Click here to read it ... of Hawaii Cancer Center, and New York’s Langone Medical ... pleural mesothelioma patients in an effort to pinpoint ...
(Date:12/15/2014)... Main Street Dental Team ( http://www.MainStreetDentalTeam.com ), Unionville’s ... new study providing evidence on the impact of 100% ... , Sufficient enough evidence already exists showing a negative ... drinks, with the onset of tooth decay. One question ... as 100% fruit juice, meaning it is completely natural ...
(Date:12/15/2014)... SIMpalm, a leading mobile app development company , ... client, which allows users to keep track of wines ... the right wine. At the center of WineMatch ... and wine information. All this information is assembled to ... that are close counterparts to one another are called ...
(Date:12/15/2014)... 15, 2014 Health Dialog, a ... today that it has received Patient Oriented Accreditation ... for its Disease Management (DM) Programs for asthma, ... coronary heart disease and diabetes. This marks the ... Health Dialog’s Disease Management (DM) Programs, reaffirming Health ...
(Date:12/15/2014)... (HealthDay News) -- Expert pilots process visual information more ... make better decisions during landings, a new study shows. ... for pilots to master, and 36 percent of all ... during final approach and landing. Researchers monitored the ... experienced pilots while they were at the controls of ...
Breaking Medicine News(10 mins):Health News:New Study Reveals Genetic Mutations That May Trigger Mesothelioma, According to Surviving Mesothelioma 2Health News:Main Street Dental Team, Unionville’s Most Innovative Dental Clinic, Comments on New Study Relating Pure Fruit Juice to Poor Oral Hygiene 2Health News:Use WinMatch Connect App to Keep Track of Wines You Like 2Health News:Health Dialog Receives NCQA Accreditation for Disease Management Programs 2Health News:Study Shows Why Expert Pilots Are Experts 2
... July 11 The Natural Orifice Surgery Consortium ... of the American Society for Gastrointestinal Endoscopy (ASGE) ... Surgeons (SAGES), today announced Olympus, continuing commitment to ... therapy known as Natural Orifice Translumenal Endoscopic Surgery(R), ...
... With the two year ... provider, has seen a 70 percent increase in women booking themselves in for botox and fillers ... ... the smoking ban upon us (1st July 2009), SurgiCare, a leading UK cosmetic surgery ...
... American ... providers of nutritional supplements and health-related content, today announced that Jim Barch has joined Healthy ... ... and ACI Capital , majority owners of Healthy Directions, LLC , one ...
... for American Medical Innovation today applauded President Obama,s appointment ... National Institutes of Health (NIH). , , (Logo: ... , "Dr. Collins is both a friend to ... said Council President Dick Gephardt. "His passion and understanding ...
... CHICAGO, July 10 Fundamental American freedoms suffered a ... rule of the Washington Board of Pharmacy took precedence over individual ... Stormans v. Selecky , overturning a lower-court decision blocking a ... Washington will now be forced to provide RU-486 (the abortion pill), ...
... Physicians for Human Rights (PHR) has ... a major New York Times story with ... investigations into alleged war crimes in Afghanistan in 2002. , ... why the Bush Administration impeded an FBI criminal probe of the ...
Cached Medicine News:Health News:NOSCAR(R) Increases NOTES(R) Research with Olympus Medical Systems Corporation Grant 2Health News:NOSCAR(R) Increases NOTES(R) Research with Olympus Medical Systems Corporation Grant 3Health News:NOSCAR(R) Increases NOTES(R) Research with Olympus Medical Systems Corporation Grant 4Health News:UK Smoking Ban Fuels Rise In Surgery 2Health News:Healthy Directions, LLC Welcomes Jim Barch as New Chief Executive Officer 2Health News:Healthy Directions, LLC Welcomes Jim Barch as New Chief Executive Officer 3Health News:Council for American Medical Innovation Applauds Appointment of Geneticist Francis Collins to Head National Institutes of Health 2Health News:Americans United for Life: Ninth Circuit Ruling on Pharmacists Endangers Fundamental Freedoms 2Health News:New Evidence that Bush Administration Impeded 3 Investigations into Alleged Massacre of Up to 2,000 Prisoners in Afghanistan 2Health News:New Evidence that Bush Administration Impeded 3 Investigations into Alleged Massacre of Up to 2,000 Prisoners in Afghanistan 3Health News:New Evidence that Bush Administration Impeded 3 Investigations into Alleged Massacre of Up to 2,000 Prisoners in Afghanistan 4
(Date:12/15/2014)... 2014 As medical device manufacturers join pharmaceutical ... language standard, content teams have a greater role to ... with the standard. Starting January 2015, Data Conversion Laboratory ... the benefits and the critical aspects of implementing SPL. ... by Howard Shatz , DCL,s SPL expert, and ...
(Date:12/15/2014)...   DaVita HealthCare Partners Inc.  (NYSE: ... and most innovative health care communities, today announced ... Clinical Research  (DCR) and  HealthCare Partners Clinical Research , ... clinical research and data analytics services, specifically in ... renal disease (ESRD), as well as primary care ...
(Date:12/15/2014)... BOSTON , December 15, 2014 ... discovery and development company, is pleased to announce the ... United States relating to its GPCR-focused drug ... US significantly strengthens the global patent estate covering Heptares, ... The suite of patents recently granted by the ...
Breaking Medicine Technology:Data Conversion Laboratory Helping Life Sciences Content Producers Understand the Impact and Benefits of Structured Product Labeling 2Data Conversion Laboratory Helping Life Sciences Content Producers Understand the Impact and Benefits of Structured Product Labeling 3DaVita Clinical Research and HealthCare Partners Clinical Research to Merge and Expand Clinical Trials and Data Analytics Capabilities 2DaVita Clinical Research and HealthCare Partners Clinical Research to Merge and Expand Clinical Trials and Data Analytics Capabilities 3DaVita Clinical Research and HealthCare Partners Clinical Research to Merge and Expand Clinical Trials and Data Analytics Capabilities 4Heptares Extends Global Patent Protection for GPCR-Focused Drug Discovery Platform With Grant of Core Patents in the United States 2
... assays are designed for ... 2000, a high-throughput, continuous ... IMMULITE 2000 offers testing ... a rapidly expanding menu ...
... radiography. The XPERT represents a research tool that ... in every digital x-ray image, thus being able ... heretofore were lost to the human eye. With ... to 8 x 8 in size, multi-color digital ...
The Solar Radius Chair is a multi-functional and cost effective working environment. It can be used for simple and advanced urodynamic studies as well as for routine gynecology investigations....
... is the ultimate in positioning ... popular accessories, the 6202 is ... of exam and treatment procedures. ... allow fast & precise positioning ...
Medicine Products: