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American Academy of Dermatology Issues New Guidelines For The Management of Psoriasis With Topical Therapies
Date:3/2/2009

e, it is not completely understood how it is inherited. However, there are at least eight chromosomes to date that researchers have identified as being linked to the genetic transmission of the disease. In addition, a number of environmental factors play an important role in the development of psoriasis, including drugs, skin trauma, infection and stress. Although psoriasis has been previously thought to be a disease affecting primarily the skin and the joints, a growing body of research suggests that psoriasis patients are at an increased risk of developing serious medical conditions, including cardiovascular disease and diabetes, particularly when their psoriasis is severe. Recent evidence has even suggested an increased overall risk of mortality in patients with severe psoriasis, especially those who have auto immune and cardiovascular diseases.

General Recommendations

Based on a comprehensive analysis of the most current studies on topical therapies for psoriasis - including corticosteroids, vitamin D analogues, combination calcipotriene/betamethasone propionate ointment, tazarotene, tacrolimus and pimecrolimus - the Academy's guidelines address patient expectations, method of application, use of concurrent therapies, length of use, application amount and patient compliance. In addition, specific recommendations for and precautions about these topical therapies used alone or with other widely used therapies in patients with more extensive psoriasis also are outlined.

According to these guidelines, topical therapies can be used safely and effectively in the majority of patients with mild to moderate psoriasis. However, topical therapies should not be used exclusively without other complementary treatments in cases of moderate to severe psoriasis or when the condition is limited but hard to manage.

Patient Expectations

Dermatologists emphasize the importance of matching patient ex
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SOURCE American Academy of Dermatology
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