Navigation Links
Alzheimer's vaccine trial a success
Date:6/7/2012

A study led by Karolinska Institutet in Sweden reports for the first time the positive effects of an active vaccine against Alzheimer's disease. The new vaccine, CAD106, can prove a breakthrough in the search for a cure for this seriously debilitating dementia disease. The study is published in the distinguished scientific journal Lancet Neurology.

Alzheimer's disease is a complex neurological dementia disease that is the cause of much human suffering and a great cost to society. According to the World Health Organisation, dementia is the fastest growing global health epidemic of our age. The prevailing hypothesis about its cause involves APP (amyloid precursor protein), a protein that resides in the outer membrane of nerve cells and that, instead of being broken down, form a harmful substance called beta-amyloid, which accumulates as plaques and kills brain cells.

There is currently no cure for Alzheimer's disease, and the medicines in use can only mitigate the symptoms. In the hunt for a cure, scientists are following several avenues of attack, of which vaccination is currently the most popular. The first human vaccination study, which was done almost a decade ago, revealed too many adverse reactions and was discontinued. The vaccine used in that study activated certain white blood cells (T cells), which started to attack the body's own brain tissue.

The new treatment, which is presented in Lancet Neurology, involves active immunisation, using a type of vaccine designed to trigger the body's immune defence against beta-amyloid. In this second clinical trial on humans, the vaccine was modified to affect only the harmful beta-amyloid. The researchers found that 80 per cent of the patients involved in the trials developed their own protective antibodies against beta-amyloid without suffering any side-effects over the three years of the study. The researchers believe that this suggests that the CAD106 vaccine is a tolera
'/>"/>

Contact: KI Press Office
pressinfo@ki.se
46-852-486-077
Karolinska Institutet
Source:Eurekalert

Page: 1 2

Related medicine news :

1. Study Suggests Vaccine May Help Kids With Brain Cancer
2. Young girls more likely to report side effects after HPV vaccine
3. Preteens More Likely to Report HPV Vaccine Side Effects
4. Vaccine yielded encouraging long-term survival rates in certain patients with NSCLC
5. Early Study Finds Some Promise for Lung Cancer Vaccine
6. From a Failed Vaccine, New Insights Into Fighting HIV
7. From herd immunity and complacency to group panic: How vaccine scares unfold
8. Brain Tumor Vaccine Shows Promise in Early Trial
9. Army researcher develops potential vaccine carrier
10. A physicians guide for anti-vaccine parents
11. Shingles Vaccine Safe, Underutilized, Study Says
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:7/13/2014)... identifies a novel genetic and molecular pathway in ... up potential new therapeutic strategies for an enigmatic ... a chronic inflammatory disorder of the esophagus. The ... foods and an over-accumulation in the esophagus of ... body,s immune system). EoE can cause a variety ...
(Date:7/13/2014)... July 13, 2014 Victorian Hotel has ... promoting the rental of bikes for its "Cycle the ... Victorian Hotel to tour the area using a rental ... Bicycle enthusiasts love to call Vancouver home, as it ... cycle travel and picturesque journeys through the countryside. Vancouver ...
(Date:7/13/2014)... Advanced boilers are preferred over conventional ... fossil fuels, produce high-capacity power, emit fewer pollutants, ... warming and climate change concerns, many countries have ... emissions and pollutants coming from fossilfuel-based power plants.North ... advance boilers market., The global power rental market ...
(Date:7/13/2014)... July 13, 2014 A Massachusetts couple ... the cancer risks associated with power morcellators ( http://www.gynecaremorcellatorlawsuit.com/ ... story to federal regulators, as they presented poignant testimony ... & Drug Administration (FDA) advisory panel meeting convened to ... to the Rochester Democrat and Chronicle, Dr. Hooman Noorchashm ...
(Date:7/13/2014)... New York, New York (PRWEB) July 13, 2014 ... mesh lawsuits ( http://www.transvaginalmeshlawsuithelp.com/ ) filed against ... the litigation’s second bellwether trial, which is expected to ... Control Order issued in the U.S. District Court, Southern ... Pretrial Conference will be held on August 7, 2014 ...
Breaking Medicine News(10 mins):Health News:Study finds cause of mysterious food allergy, suggests new treatment strategy 2Health News:Study finds cause of mysterious food allergy, suggests new treatment strategy 3Health News:Victorian Hotel Creates Excitement by Adding "Cycle the City" Bike Rentals for Its Vancouver Hotel Rooms 2Health News:North America Advanced Boilers Market is Expected to Reach $518.7billion by 2019 - New Report by MicroMarket Monitor 2Health News:North America Advanced Boilers Market is Expected to Reach $518.7billion by 2019 - New Report by MicroMarket Monitor 3Health News:Couple Who Brought Attention to Morcellator Cancer Risks Testify on Second Day of FDA Advisory Panel Meeting, Bernstein Liebhard LLP Reports 2Health News:Couple Who Brought Attention to Morcellator Cancer Risks Testify on Second Day of FDA Advisory Panel Meeting, Bernstein Liebhard LLP Reports 3Health News:Couple Who Brought Attention to Morcellator Cancer Risks Testify on Second Day of FDA Advisory Panel Meeting, Bernstein Liebhard LLP Reports 4Health News:Ethicon Vaginal Mesh Lawsuits Move Forward, As Federal Court Schedules Pretrial Conference for Second Bellwether Case, Bernstein Liebhard LLP Reports 2Health News:Ethicon Vaginal Mesh Lawsuits Move Forward, As Federal Court Schedules Pretrial Conference for Second Bellwether Case, Bernstein Liebhard LLP Reports 3Health News:Ethicon Vaginal Mesh Lawsuits Move Forward, As Federal Court Schedules Pretrial Conference for Second Bellwether Case, Bernstein Liebhard LLP Reports 4
... , THURSDAY, April 5 (HealthDay News) -- For people ... be just as good as having the appendix removed, ... hundreds of patients to determine that treatment with antibiotics ... been the so-called "gold standard" of care for an ...
... (HealthDay News) -- Patients with digestive disorders such ... levels of radiation from diagnostic imaging tests, a new ... patients with gastrointestinal disorders between 1999 and 2009, ... diagnostic imaging tests such as computed tomography (CT) imaging. ...
... Doheny HealthDay Reporter , THURSDAY, April 5 (HealthDay ... mammogram may be at higher long-term risk of developing breast ... a new Danish study. However, the link between false-positive ... among women who had been screened from the early 2000s ...
... common among long-term survivors of acute lung injury ... a telephone-based test battery, according to a new ... as an important outcome among survivors of critical ... has not been assessed in a multi-center trial, ...
... , ,Airport security screening has increased substantially during the ... rise. According to the American Academy of Orthopaedic ... (THR) were performed in the United States. A ... Security Checkpoints: How Has Heightened Security Affected Patients," ...
... 5, 2012 - Old houses and vacant lots may not look ... is better than gold. Excavations over the years can create ... if dirt and debris ended up mixed in a blender then ... one scientist and geologist is finding some of the city,s abandoned ...
Cached Medicine News:Health News:Study Finds Antibiotics Best for Appendicitis 2Health News:Study Finds Antibiotics Best for Appendicitis 3Health News:Diagnostic Scans Tied to Radiation Risk for Gastro Patients 2Health News:False-Positive Mammogram Results May Turn Out Not to Be: Study 2Health News:False-Positive Mammogram Results May Turn Out Not to Be: Study 3Health News:Long-term neuropsychological impairment is common in acute lung injury survivors 2Health News:Clinical news alert from the American Academy of Orthopaedic Surgeons 2Health News:History of abandoned urban sites found stored in soil 2
(Date:7/11/2014)... 2014 /PRNewswire-iReach/ -- VAPETEK™, Inc. has announced a ... use in portable vaporizers, which contains CBD, or ... cannabis, cannabidiol offers consumers a THC-free product made ... vaporizer technology. Photo - http://photos.prnewswire.com/prnh/20140711/126344 ... different compounds which are currently known, two of ...
(Date:7/11/2014)... , July 11, 2014 ... "Scintillator Market by Composition of Material, Application (Healthcare, ... others), End Product (Personal Instrument, Hand-Held Instruments, Fixed, ... and Analysis to 2013 - 2020", published by MarketsandMarkets, the ... CAGR of 5.62% from 2014 to 2020, and ...
(Date:7/11/2014)... ALBANY, New York , July 11, 2014 /PRNewswire/ ... published by Transparency Market Research "Endoscopy Devices Market (Endoscopes, ... Analysis, Size, Share, Growth, Trends and Forecast, 2013-2019" the ... billion in 2012 and is expected to grow at ... reach an estimated value of USD 36.9 billion in ...
Breaking Medicine Technology:VAPETEK Releases CBD-Infused eLiquid For The Consumer Market 2Scintillator Market will be worth $479.16 Million by 2020 2Scintillator Market will be worth $479.16 Million by 2020 3Scintillator Market will be worth $479.16 Million by 2020 4Global Endoscopy Devices Market is Expected to Reach USD 36.9 Billion by 2019: Transparency Market Research 2Global Endoscopy Devices Market is Expected to Reach USD 36.9 Billion by 2019: Transparency Market Research 3Global Endoscopy Devices Market is Expected to Reach USD 36.9 Billion by 2019: Transparency Market Research 4Global Endoscopy Devices Market is Expected to Reach USD 36.9 Billion by 2019: Transparency Market Research 5Global Endoscopy Devices Market is Expected to Reach USD 36.9 Billion by 2019: Transparency Market Research 6
... Feb. 17, 2012 Angeion Corporation (NASDAQ: ANGN ) ... the first quarter fiscal 2012, ended January 31, 2012. The call ... The Company will report financial results for the first quarter fiscal ... 2012. Those wishing to participate can dial (877) ...
... Inc. (Nasdaq: ALXA ), today announced that it ... to purchase shares of its common stock in an underwritten ... book-running manager in the offering. The offering ... assurance as to whether or when the offering may be ...
Cached Medicine Technology:Angeion Corporation to Report First Quarter Fiscal 2012 Financial Results on Tuesday, February 28, 2012 2Alexza Announces Proposed Public Offering of Common Stock and Warrants 2Alexza Announces Proposed Public Offering of Common Stock and Warrants 3Alexza Announces Proposed Public Offering of Common Stock and Warrants 4
... reference laboratory and a worldwide leader in ... an extensive test menu of highly complex ... anatomic pathology. Owned by the University of ... half of the nation's university teaching hospitals ...
... national reference laboratory and a worldwide leader ... offers an extensive test menu of highly ... and anatomic pathology. Owned by the University ... than half of the nation's university teaching ...
... a national reference laboratory and a worldwide ... ARUP offers an extensive test menu of ... clinical and anatomic pathology. Owned by the ... more than half of the nation's university ...
... reference laboratory and a worldwide leader in ... an extensive test menu of highly complex ... anatomic pathology. Owned by the University of ... half of the nation's university teaching hospitals ...
Medicine Products: