Navigation Links
Alzheimer's Research Brings Progress, Setbacks
Date:7/18/2008

Once-promising vaccine fails to ease symptoms, but old drug offers new hope

FRIDAY, July 18 (HealthDay News) -- It's one step forward, one step back in the search for treatments against Alzheimer's disease.

In one of two studies in the July 19 issue of The Lancet, an older drug called dimebon significantly improved Alzheimer's symptoms. But in a second report, a once-promising vaccine failed to prevent the progression of Alzheimer's -- even though it cleared dementia-linked amyloid plaques in the brain.

This week's issue of the journal is devoted to research into the causes and treatment of dementia, including Alzheimers disease. According to the U.S. National Institutes of Health, an estimated 4.5 million Americans have Alzheimer's disease, which is thought to affect one in 20 people between the ages of 65 and 74. The estimated rate goes up to nearly half of those aged 85 and older.

In one study, British researchers led by Dr. Clive Holmes, from the Memory Assessment and Research Centre at Moorgreen Hospital in Southampton, analyzed data on 80 Alzheimer's patients who were treated with an experimental vaccine that for now is dubbed AN1792.

The vaccine is targeted at the removal of amyloid protein plaques that clump around brain cells in increasing numbers as Alzheimer's progresses. The theory was that dementia could be slowed or reversed once the plaques were cleared, and experiments in animals have shown that removing these plaques improves brain function.

Indeed, long-term follow-up of Alzheimer's patients treated with AN1792 did show, "a reduction in the number of plaques in the brains of patients -- in some cases there was a virtually complete removal of plaques," Holmes said.

But there was a catch. "Crucially, there was no evidence that the patients benefited by the removal of plaques and even those subjects with virtually complete removal continued to deteriorate and ha
'/>"/>

Copyright©2008 ScoutNews,LLC.
All rights reserved  

Page: 1 2 3 4

Related medicine news :

1. Alzheimers Research Target May Be a Dead End
2. Stanford researchers find culprit in aging muscles that heal poorly
3. Children of depressed moms do better when dad is involved, SLU researcher finds
4. UCLA researchers identify markers that may predict diabetes in still-healthy people
5. Mayo Clinic researchers discover new diagnostic test for detecting infection in prosthetic joints
6. New research shows how chronic stress worsens neurodegenerative disease course
7. New research explores newborn in-hospital weight loss
8. Research may unlock mystery of autisms origin in the brain
9. Bipolar disorder relapses halved by Melbourne researchers
10. HIVs impact in Zimbabwe explored in new research
11. U.S. Research Funding Continues to Flatten as U.S. Health Costs Climb - in August 31 Science
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Alzheimer's Research Brings Progress, Setbacks
(Date:9/2/2014)... CITY, GA (PRWEB) September 02, 2014 Last ... whole new level with the launch of a luxurious line ... to announce that the SEA ISLAND COTTON Socks are joining ... compression level, giving more people the comfort of natural cotton ... COTTON Socks, they are surprised to find socks as soft ...
(Date:9/2/2014)... FL (PRWEB) September 02, 2014 Alliance ... targeting and multi-channel email marketing is pleased to announce ... market, Firearms & Freedom as well as ... properties represent more than one million concerned Americans who ... advertising. , “We are honored to continue providing ...
(Date:9/2/2014)... hospitalized, but your outpatient doctor does not know? ... follow-up care, but your doctor does not have ... Missing or incomplete communication from hospitals to outpatient ... experiences and lead to hospital readmissions. , ... can improve hospitals, communication during patient care transitions. ...
(Date:9/2/2014)... many health risks, including heart disease and diabetes, but ... to mitigate one often-overlooked risk: not buckling up in ... H. Jacobson, a professor of computer science and of ... with a decrease in seatbelt usage. However, these effects ... , "Primary seatbelt laws lead to increased use of ...
(Date:9/2/2014)... Farmington, New York (PRWEB) September 02, 2014 ... Millworks is making it easy to create a consistent look ... the physical structure, to the floor you walk on and ... shop for all custom reclaimed wood designs. , “We’re ... customers to our product line. It saves time, adds consistency, ...
Breaking Medicine News(10 mins):Health News:SIGVARIS’ Luxury Line of Compression Socks, SEA ISLAND COTTON, Now Available in Stronger Compression Level 2Health News:ASG Continues to Bring New Lists to Market 2Health News:ASG Continues to Bring New Lists to Market 3Health News:Can data motivate hospital leaders to improve care transitions? 2Health News:Seatbelt laws encourage obese drivers to buckle up 2Health News:Pioneer Millworks Now Offering Products Beyond Reclaimed Wood Flooring 2
... The Advertising Standards Authority ruled yesterday that a Walkers ... salt content.// ,According to the industry watchdog ... in its crisps to "7% of your guideline daily ... did not apply to all Walkers crisps. They have ...
... scheme launched in Madhya Pradesh to help malnourished children is ... Shakti scheme was unveiled to aid the 5.7 million malnourished ... years in age, Grassroots Features reported. ,Two-and-a-half-year-old Prem ... 4.2 kg when she was brought to the Bal Shakti ...
... to a new study at the University of Michigan Depression ... not getting// any treatment nor are the ones with the ... ,In the latest issue of General Hospital Psychiatry, the ... of treatment, are not getting enough. ,Without adequate treatment ...
... Bill Gates said inadequate access to treatment and continued discrimination ... in addresses to the largest ever AIDS conference under way ... stigma and stop people from being scared to know their ... Gates have donated billions of dollars to combat the spread ...
... the use of Herceptin in advanced breast cancer patients led ... percent of patients treated with Herceptin// , which no ... of the damage to the heart can be remedied with ... in the Journal of Clinical Oncology, concludes that use of ...
... that reduced levels of testosterone, which is the male sex ... whether a man would die early. ,US scientists ... 858 military veterans aged over 40. Reporting their findings in ... low hormone levels had an 88% increased risk of death ...
Cached Medicine News:Health News:Scheme for Combating Malnourishment in MP Children Yet to Pick Up 2Health News:No therapy for most of the pregnant women with depression 2Health News:No therapy for most of the pregnant women with depression 3Health News:No therapy for most of the pregnant women with depression 4Health News:Herceptin Use May Enhance Cardiac Toxicity, Study 2Health News:Herceptin Use May Enhance Cardiac Toxicity, Study 3Health News:Low Testosterone Linked With Early Death 2
(Date:9/2/2014)...  Boston Scientific Corporation (NYSE: BSX ... purchase the Interventional business of Bayer AG. The ... offer physicians and healthcare systems a more complete ... The addition of the Bayer Interventional ... Boston Scientific strategy to provide a comprehensive portfolio ...
(Date:9/2/2014)... , Sept. 2, 2014  Volcano Corporation ... focused on improving patient and economic outcomes on ... minimally invasive coronary and peripheral visualization, physiology diagnostics ... participating in the Morgan Stanley Healthcare conference on ... Scott Huennekens , president and chief executive ...
(Date:9/2/2014)... SAN DIEGO , Sept. 2, 2014  Arena ... that the US Food and Drug Administration (FDA) has ... of pulmonary arterial hypertension. "The FDA ... clinical data submissions from sponsors to identify and designate ... help advance the evaluation and development of such products," ...
Breaking Medicine Technology:Boston Scientific Closes Acquisition Of Interventional Business Of Bayer AG 2Boston Scientific Closes Acquisition Of Interventional Business Of Bayer AG 3Boston Scientific Closes Acquisition Of Interventional Business Of Bayer AG 4Boston Scientific Closes Acquisition Of Interventional Business Of Bayer AG 5Arena Pharmaceuticals' APD811 Granted Orphan Drug Status for Pulmonary Arterial Hypertension 2Arena Pharmaceuticals' APD811 Granted Orphan Drug Status for Pulmonary Arterial Hypertension 3Arena Pharmaceuticals' APD811 Granted Orphan Drug Status for Pulmonary Arterial Hypertension 4
... national reference laboratory and a worldwide leader ... offers an extensive test menu of highly ... and anatomic pathology. Owned by the University ... than half of the nation's university teaching ...
... national reference laboratory and a worldwide leader ... offers an extensive test menu of highly ... and anatomic pathology. Owned by the University ... than half of the nation's university teaching ...
... a national reference laboratory and a worldwide ... ARUP offers an extensive test menu of ... clinical and anatomic pathology. Owned by the ... more than half of the nation's university ...
... national reference laboratory and a worldwide leader ... offers an extensive test menu of highly ... and anatomic pathology. Owned by the University ... than half of the nation's university teaching ...
Medicine Products: