Navigation Links
Alzheimer's Med Seems Ineffective in Those With Down Syndrome
Date:1/10/2012

TUESDAY, Jan. 10 (HealthDay News) -- A drug commonly used to treat patients with Alzheimer's disease does not appear to be effective for people older than 40 years who have Down syndrome and Alzheimer's, according to a new study.

Although previous animal studies of the Alzheimer's drug, memantine, showed promising results in mice with Down syndrome, this new study of people with Down syndrome aged 40 and older revealed the opposite, the researchers reported in the Jan. 9 online edition of The Lancet.

Memantine was given to 88 people with Down syndrome for one year, while another 85 patients received a placebo (the "control" group). Some of the participants had Alzheimer's and some didn't.

The investigators found that the brain function of the people in both groups declined equally.

Serious adverse effects were experienced by 11 percent of the group that took the medication. Meanwhile, 7 percent of the placebo group had similar adverse events. Five people from the medication group died because of these events, compared to four in the control group.

"Memantine is not an effective treatment in this group of patients. We believe that this robust finding will have implications for clinical practice and research strategy in the future. Specifically, therapies that are beneficial for people with Alzheimer's disease are not necessarily effective for the treatment of cognitive impairment or dementia in the context of Down syndrome," the study's author, Clive Ballard, a professor at the Wolfson Centre for Age-Related Diseases at King's College London, said in a journal news release.

Because nearly 40 percent of people with Down syndrome over 60 years of age are diagnosed with dementia, the study authors pointed out that more research is needed to determine the best way to treat dementia in these individuals.

"Further investment is urgently needed to develop treatments that are effective in this important group of people," the study's co-author, Anne Corbett, research manager at Alzheimer's Society (U.K.), stated in the news release.

More information

The U.S. National Institute of Neurological Disorders and Stroke provides more information on Alzheimer's disease.

-- Mary Elizabeth Dallas

SOURCE: The Lancet, news release, Jan. 9, 2012


'/>"/>
Copyright©2010 ScoutNews,LLC.
All rights reserved  

Related medicine news :

1. Surgery Seems Most Effective for Herniated Discs
2. 1st Artificial Windpipe Made With Stem Cells Seems Successful
3. Newer Drug Seems Better at Controlling Lupus Kidney Complication
4. Regular Exercise Seems to Guard Against Migraine
5. Diabetes Education Seems to Help Improve Blood Sugar Control
6. Heart Defect Seems to Pose Low Risk of Aorta Tear
7. Special Talk Therapy Seems to Help Dying Patients
8. Satisfaction With Life Seems Good for the Heart
9. When It Comes to Memory, Practice Seems to Make Perfect
10. Ovulation Seems to Aid Womens Gaydar
11. Experimental Vaccine Seems to Cure Prostate Cancer in Mice
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Alzheimer's Med Seems Ineffective in Those With Down Syndrome
(Date:8/17/2017)... ... ... Pot Valet is a leading provider of premium medical-grade cannabis in California. ... soon, every state in the country, the company offers patients safe, legal, and discreet ... , According to Pot Valet, all California patients have the legal right to ...
(Date:8/17/2017)... (PRWEB) , ... August 17, 2017 , ... ... Great Employers , an international competition, were announced today. The awards recognize the ... and suppliers who help to create and drive great places to work. , ...
(Date:8/16/2017)... , ... August 16, 2017 , ... The next Patient ... being accepted. , Students who successfully complete the seven-week long Patient Care Academy ... Assistant (CNA). The average starting salary for a CNA in Kalamazoo is $24,428.* , ...
(Date:8/16/2017)... Houston, Texas (PRWEB) , ... August 16, 2017 , ... ... Community Credit Union's Stars in the Classroom and will win a visit by a ... in grades K-12 who are at least five years old can visit texanschecking.com/stars to ...
(Date:8/16/2017)... ATLANTA, Georgia (PRWEB) , ... August 16, 2017 ... ... practice in Atlanta, opened their doors. They celebrate 30 years in business this ... to create an up-to-date, inviting, tranquil space to serve their patients. , ...
Breaking Medicine News(10 mins):
(Date:8/15/2017)... Inc., the creator of the drug Truveta for the treatment ... IPO. The United States spends approximately ... prescription epilepsy drug being $450.00-$1200.00 for a one month supply. ... AXIUM PHARMACEUTICALS, INC ... is the fact that Americans spent $42 billion on anxiety medications last ...
(Date:8/11/2017)... , Aug. 11, 2017 DarioHealth Corp. (NASDAQ: ... health and big data solutions, today announced that it ... August 14 and host a conference call at 9:00am ... operating and financial results and its strategy and outlook ... hosted by Erez Raphael , Chief Executive Officer, ...
(Date:8/7/2017)... 7, 2017 Insightin Health, provider of ... and engagement, announced the selection of Michael ... Development, effective as of February 2017. In this role, ... strategy for our clients. Wood brings with him ... and business analytics within the healthcare industry. Wood ...
Breaking Medicine Technology: