Navigation Links
Alzheimer's-Like Memory Loss Reversed in Mice
Date:2/29/2012

By Randy Dotinga
HealthDay Reporter

WEDNESDAY, Feb. 29 (HealthDay News) -- New research in mice suggests that Alzheimer's disease triggers a protein that contributes to the breakdown of the brain's memory.

If the findings are confirmed in humans, they could solve part of the puzzle of how gunk-like substances in the brain cause Alzheimer's disease and lead to memory loss. It's conceivable that a drug could be developed to turn off the process and reverse memory problems -- as the researchers managed to do with mice.

For now, the research is in its early stages and it could take five to 10 years to get to drug experiments in humans, said study author Johannes Graff, a postdoctoral researcher at Massachusetts Institute of Technology. Even if a drug is developed using this knowledge, it would only treat the symptoms of Alzheimer's and not the root cause, he said.

But it could mark a major advance to be able to turn around the memory problems spawned by Alzheimer's, Graff said, adding, "We can show that this is potentially reversible."

There are more than 5 million Americans who have been diagnosed with Alzheimer's, according to the U.S. National Institute of Neurological Disorders and Stroke (NINDS).

Researchers believe that Alzheimer's disease begins when the brain becomes clogged by substances known as beta-amyloid plaques and tau tangles. The new research in mice, Graff said, suggests that when a protein known as histone deacetylase 2 (HDAC2) is triggered, it shuts down genes that are crucial to memory. By preventing the buildup of HDAC2 in the brains of mice, the researchers were able to protect against memory loss.

Brain tissue from deceased Alzheimer's patients also showed higher levels of HDAC2 in regions where memory and learning are known to be located, the scientists added, and they theorized that the accumulation of beta amyloid deposits in the brain may be what sends HDAC2 into overdri
'/>"/>

Copyright©2010 ScoutNews,LLC.
All rights reserved  

Page: 1 2

Related medicine news :

1. Alzheimers-Linked Brain Plaques May Affect Memory in Healthy People
2. Decaffeinated coffee preserves memory function by improving brain energy metabolism
3. Men more likely to have an accurate memory of unpleasant experiences
4. Could Nicotine Patches Help Stave Off Memory Loss?
5. Silent Strokes Linked to Memory Loss in Elderly: Study
6. New clues as to why some older people may be losing their memory
7. Exercise/memory research for Parkinsons
8. Pycnogenol® found to improve memory and test scores in college students in new clinical trial
9. Very Low Birth Weight May Affect Adult Memory, IQ
10. Seniors Memory Doesnt Seem to Improve With Sleep: Study
11. Breast Cancer Chemo Tied to Memory Troubles
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Alzheimer's-Like Memory Loss Reversed in Mice
(Date:10/19/2014)... 2014 Recently, BambooIndustry.com, one of the ... new range of bamboo deckings . Moreover, the ... items; they are now available at deeply discounted rates. ... is hard to overstate the significance of online business ... online services. The company’s workers are striving to deliver ...
(Date:10/19/2014)... (PRWEB) October 20, 2014 Recently, ... and announced that JustHost, GoDaddy and HostMonster are ... market. VPS (Virtual Private Server) is the method ... servers, each of which has the appearance and ... That is why the site pays close attention ...
(Date:10/19/2014)... October 20, 2014 Stephen T. Greenberg, M.D., ... nominated for the 10th consecutive year as one of Long ... Greenberg was also been nominated as the best provider for ... nominated as best Day Spa and best Laser Treatment center ... 14th and readers can vote for the contest once per ...
(Date:10/19/2014)... 2014 The federal litigation involving ... move forward in Massachusetts federal court, where more ... the dialysis medication, Bernstein Liebhard LLP reports. ... shows 2,127 claims now filed over GranuFlo and ... U.S. District Court, District of Massachusetts. Plaintiffs in ...
(Date:10/19/2014)... October 19, 2014 When patients and their ... Hospital and turn the corner to face the Hummingbird Gift ... hospital volunteers to sell there. There’s unique home décor. Cooking ... so obvious, though, is the importance this small gift shop ... Tappahannock and Northern Neck community of the future. , ...
Breaking Medicine News(10 mins):Health News:High Quality Bamboo Deckings, New Items Unveiled By BambooIndustry.com 2Health News:The Best VPS Hosting Suppliers In The Market Unveiled By Top10BestSEOHosting.com 2Health News:Dr. Stephen T. Greenberg – Nominated for the 10th Consecutive Year for One of Long Island’s Best Cosmetic Surgeons for 2015 by the Long Island Press 2Health News:More than 2,100 GranuFlo Lawsuits Now Filed in Federal Dialysis Drug Litigation, Bernstein Liebhard LLP Reports 2Health News:More than 2,100 GranuFlo Lawsuits Now Filed in Federal Dialysis Drug Litigation, Bernstein Liebhard LLP Reports 3Health News:More than 2,100 GranuFlo Lawsuits Now Filed in Federal Dialysis Drug Litigation, Bernstein Liebhard LLP Reports 4Health News:Riverside Tappahannock Hospital Capital Campaign Gets Boost From Community Through Gift Shop 2Health News:Riverside Tappahannock Hospital Capital Campaign Gets Boost From Community Through Gift Shop 3
... Given Green Light by Insurers, SANTA MONICA, ... California health regulators acknowledged that patients,should be able ... their health coverage. Yet the details of the ... insurers, said Consumer Watchdog,allowing them in many cases ...
... aciclovir shows no added benefit , , THURSDAY, June 19 ... reduce the risk of HIV-1 infection in people who ... U.S. study finds. , Previous research has shown that ... common cause of genital herpes -- increases the risk ...
... Visit redcrossracing.com, WASHINGTON, June 19 3M Company ... recently devastated,by severe weather in the Midwest. For the ... and toll-free number, 1-800-RED-CROSS, will be,displayed on the TV ... also donated,approximately 25,000 units of hand sanitizer, insect repellant ...
... Ind., June 19 Zimmer Holdings, Inc.,(NYSE: ... that it will partner with AmeriCares,one of ... donations, to support emergency response and ongoing ... at $1 million to,three of AmeriCares, primary ...
... lead to more effective treatments for diarrhea worldwide, study says ... they,ve identified an enzyme that may help dysentery-causing amoeba evade ... lead to new ways to fight dysentery, a form of ... and is a serious health threat in many regions. ...
... Center,is pleased to announce that KARE 11 TV has ... Distinction., Over the years, Twin Cities based KARE ... 264 (275 including 2008) community,volunteers. The story of each ... Courage Center volunteers (including three pairs of,volunteers) have been ...
Cached Medicine News:Health News:PacifiCare 'Rescission' Settlement Gives Lip Service to Patient Losses But Stacks Legal Deck in Favor of Insurers 2Health News:Herpes Suppression May Not Prevent HIV Infection 2Health News:3M Company Supports Red Cross Relief Efforts through Red Cross Racing 2Health News:3M Company Supports Red Cross Relief Efforts through Red Cross Racing 3Health News:Zimmer Holdings to Partner with AmeriCares for Global Product Donation Program 2Health News:Zimmer Holdings to Partner with AmeriCares for Global Product Donation Program 3Health News:Scientists ID Enzyme That Allows Dysentery Amoeba to Hide 2Health News:Courage Center Honored With KARE TV's 2008 Eleven Who Care Agency of Distinction 2
(Date:10/17/2014)... -- Investor-Edge has initiated coverage on the ... ), NPS Pharmaceuticals Inc. (NASDAQ: NPSP ), ... Inc. (NASDAQ: MNTA ), and Catalyst Pharmaceutical ... companies can be accessed at: http://investor-edge.com/register . ... ended on a mixed note as the Dow Jones ...
(Date:10/17/2014)... -- Ameritox SM , the nation,s leader in medication monitoring ... , M.D., as Chief Medical Officer. In this role, ... for healthcare providers, patients and managed care plans.   ... variety of healthcare companies that have provided him with ... health sides of Ameritox,s business. He most recently served ...
(Date:10/17/2014)... ANGELES , Oct. 17, 2014 CytRx ... and development company specializing in oncology, announced that data ... aldoxorubicin for the treatment of first-line soft tissue sarcoma ... at the 2014 Connective Tissue Oncology Society (CTOS) Annual ... Berlin , Germany. Due to the longer ...
Breaking Medicine Technology:Biotech Equities Technical Briefing - Arena Pharma, NPS Pharma, XOMA, Momenta Pharma, and Catalyst Pharma Partners 2Biotech Equities Technical Briefing - Arena Pharma, NPS Pharma, XOMA, Momenta Pharma, and Catalyst Pharma Partners 3Biotech Equities Technical Briefing - Arena Pharma, NPS Pharma, XOMA, Momenta Pharma, and Catalyst Pharma Partners 4Biotech Equities Technical Briefing - Arena Pharma, NPS Pharma, XOMA, Momenta Pharma, and Catalyst Pharma Partners 5Ameritox Appoints New Chief Medical Officer 2CytRx to Present Data from Global Phase 2b Clinical Trial of Aldoxorubicin in First-Line Soft Tissue Sarcoma at 2014 CTOS Annual Meeting 2CytRx to Present Data from Global Phase 2b Clinical Trial of Aldoxorubicin in First-Line Soft Tissue Sarcoma at 2014 CTOS Annual Meeting 3CytRx to Present Data from Global Phase 2b Clinical Trial of Aldoxorubicin in First-Line Soft Tissue Sarcoma at 2014 CTOS Annual Meeting 4CytRx to Present Data from Global Phase 2b Clinical Trial of Aldoxorubicin in First-Line Soft Tissue Sarcoma at 2014 CTOS Annual Meeting 5CytRx to Present Data from Global Phase 2b Clinical Trial of Aldoxorubicin in First-Line Soft Tissue Sarcoma at 2014 CTOS Annual Meeting 6
... (OTC: IDTA) CEO Yaacov Shoham today announced the following order. ... sales in many new markets, including Australia-a most important market ... order for 2000 detectors from the Australian representative GK ... the past several months we have been in continuous contact ...
... 13, 2011 Quest Diagnostics Incorporated (NYSE: DGX ... services, announced today that it will report third quarter 2011 ... will hold its quarterly conference call with investors to discuss ... The public may access the conference call through ...
Cached Medicine Technology:International Drug & Explosives Detection Company IDenta Corp. Receives Order From Australia 2Quest Diagnostics to Release Third Quarter 2011 Financial Results 2
... ARUP Laboratories is a national reference ... laboratory research and development. ARUP offers an ... unique medical tests in clinical and anatomic ... ARUP Laboratories' clients include more than half ...
... national reference laboratory and a worldwide leader ... offers an extensive test menu of highly ... and anatomic pathology. Owned by the University ... than half of the nation's university teaching ...
... ARUP Laboratories is a national reference ... laboratory research and development. ARUP offers an ... unique medical tests in clinical and anatomic ... ARUP Laboratories' clients include more than half ...
... Laboratories is a national reference laboratory and ... and development. ARUP offers an extensive test ... tests in clinical and anatomic pathology. Owned ... clients include more than half of the ...
Medicine Products: