Navigation Links
Alzheimer's Drugs Also Treat Behavioral, Psych Problems
Date:12/17/2008

Therapy effective at same dosage used to improve cognitive impairment, study says

WEDNESDAY, Dec. 17 (HealthDay News) -- Drugs used to treat Alzheimer's patients' cognitive symptoms are also a safe and effective therapy for behavioral and psychological symptoms such as aggression, wandering and paranoia, according to U.S. researchers.

They reviewed nine studies that examined the effectiveness of three popular cholinesterase inhibitors in managing Alzheimer's patients' behavioral and psychological symptoms, and found the drugs were effective at the same dosage used to improve cognitive impairment.

The study was published in the December issue of Clinical Interventions in Aging.

About 90 percent of Alzheimer's patients have behavioral and psychological symptoms. Cholinesterase inhibitors boost levels of a brain chemical called acetylcholine, which assists memory, thought and judgment.

"There is a need for safe alternatives to the antipsychotic drugs currently used to manage the behavioral and psychological symptoms of Alzheimer's disease. The results of the studies we analyzed are encouraging and suggestive that cholinesterase inhibitors are safe and effective alternatives," review co-author Dr. Malaz Boustani, an assistant professor of medicine at the Indiana University School of Medicine, said in a university news release.

"However, [cholinesterase inhibitors] are underutilized and typically prescribed for less than three months and for less than 10 percent of patients with Alzheimer's disease. Our findings might provide clinicians with useful data to justify the appropriate use of these medications," said Boustani, a researcher at the IU Center for Aging Research and chief research officer of the Indianapolis Discovery Network for Dementia.

"This class of medications has already been approved the Food and Drug Administration to manage symptoms of Alzheimer's type dementia, although the potential benefits on behavioral symptoms are not frequently identified by many prescribers," study co-author Noll Campbell, a clinical pharmacy specialist in geriatric psychiatry with Wishard Health Services, said in the news release. The use of cholinesterase inhibitors could reduce "the use of more harmful medications that are needed to control [dementia-related] behaviors."

More information

The U.S. National Institute on Aging has more about Alzheimer's medications.



-- Robert Preidt



SOURCE: Indiana University, news release, Dec. 9, 2008


'/>"/>
Copyright©2008 ScoutNews,LLC.
All rights reserved  

Related medicine news :

1. Alzheimers Research Target May Be a Dead End
2. FDA Adds Suicide Warning to Epilepsy Drugs
3. UIC researchers hunting drugs for devastating parasitic disease
4. China Sky One Medical, Inc. Obtains Production Rights for Two Additional Drugs
5. Sanofi-aventis U.S. Announces Increased Access to Drugs for Low Income Patients Through Expanded PAP Programs
6. FDA Puts Black-Box Warning on Bowel-Cleansing Drugs
7. Cancer drugs in the pipeline
8. A new class of anti-inflammatory drugs
9. 2 Diabetes Drugs Double Fracture Risk in Women
10. Two common diabetes drugs double the risk of fractures in women
11. Popular class of diabetes drugs doubles risk of fractures in women
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Alzheimer's Drugs Also Treat Behavioral, Psych Problems
(Date:5/31/2016)... Atlanta, GA (PRWEB) , ... May 31, 2016 ... ... Contact Center Solutions , today announced it has been included by Gartner, ... 2016 report mentions a wide range of Contact Center Infrastructure technologies, some of ...
(Date:5/31/2016)... ... May 31, 2016 , ... Splashtop Inc., the worldwide leader ... with e-Jan Networks Co., the leading provider of secure mobile remote access solution ... Networks’s leading CACHATTO remote access solution. Splashtop for CACHATTO will be ...
(Date:5/31/2016)... ... May 31, 2016 , ... St. Joseph Medical Center (SJMC) ... exchange, which enables physicians at SJMC’s two hospital campuses, downtown and in the ... in the exchange. SJMC’s membership in the health information exchange underscores the hospital’s ...
(Date:5/31/2016)... , ... May 31, 2016 , ... Twenty years ago ... experience, rather than trying to silence the voices they hear. But this approach has ... itself. , The method has steadily gained credibility and now is used around the ...
(Date:5/31/2016)... ... 31, 2016 , ... The University of Tennessee Medical Center ... the latest in Clinical Patient Pod (CPP) technologies provided through Jvion’s ... into the clinical workflow. These insights are empowering the more than 30 case ...
Breaking Medicine News(10 mins):
(Date:5/31/2016)... May 31, 2016   Plexus Technology Group, ... anesthesia information management systems (AIMS), is pleased to ... as Vice President of Technology. In this new ... aspects of the company,s technological development. He will ... to determine the expansion of new products, product ...
(Date:5/31/2016)... , May 31, 2016 ... market is progressing at a CAGR of 10.6% within ... was valued at US$0.46 bn in 2013. Owing to ... expected to reach US$0.88 bn by the end of ... derived from the market,s holistic representation in a research ...
(Date:5/31/2016)... , May 31, 2016 ... the initiation of a first-in-human clinical trial of its ... molecule - S101 is currently being developed for the ... study is designed to evaluate the safety and tolerability ... at several sites across the United States ...
Breaking Medicine Technology: