Navigation Links
Alzheimer's Drugs Also Treat Behavioral, Psych Problems

Therapy effective at same dosage used to improve cognitive impairment, study says

WEDNESDAY, Dec. 17 (HealthDay News) -- Drugs used to treat Alzheimer's patients' cognitive symptoms are also a safe and effective therapy for behavioral and psychological symptoms such as aggression, wandering and paranoia, according to U.S. researchers.

They reviewed nine studies that examined the effectiveness of three popular cholinesterase inhibitors in managing Alzheimer's patients' behavioral and psychological symptoms, and found the drugs were effective at the same dosage used to improve cognitive impairment.

The study was published in the December issue of Clinical Interventions in Aging.

About 90 percent of Alzheimer's patients have behavioral and psychological symptoms. Cholinesterase inhibitors boost levels of a brain chemical called acetylcholine, which assists memory, thought and judgment.

"There is a need for safe alternatives to the antipsychotic drugs currently used to manage the behavioral and psychological symptoms of Alzheimer's disease. The results of the studies we analyzed are encouraging and suggestive that cholinesterase inhibitors are safe and effective alternatives," review co-author Dr. Malaz Boustani, an assistant professor of medicine at the Indiana University School of Medicine, said in a university news release.

"However, [cholinesterase inhibitors] are underutilized and typically prescribed for less than three months and for less than 10 percent of patients with Alzheimer's disease. Our findings might provide clinicians with useful data to justify the appropriate use of these medications," said Boustani, a researcher at the IU Center for Aging Research and chief research officer of the Indianapolis Discovery Network for Dementia.

"This class of medications has already been approved the Food and Drug Administration to manage symptoms of Alzheimer's type dementia, although the potential benefits on behavioral symptoms are not frequently identified by many prescribers," study co-author Noll Campbell, a clinical pharmacy specialist in geriatric psychiatry with Wishard Health Services, said in the news release. The use of cholinesterase inhibitors could reduce "the use of more harmful medications that are needed to control [dementia-related] behaviors."

More information

The U.S. National Institute on Aging has more about Alzheimer's medications.

-- Robert Preidt

SOURCE: Indiana University, news release, Dec. 9, 2008

Copyright©2008 ScoutNews,LLC.
All rights reserved  

Related medicine news :

1. Alzheimers Research Target May Be a Dead End
2. FDA Adds Suicide Warning to Epilepsy Drugs
3. UIC researchers hunting drugs for devastating parasitic disease
4. China Sky One Medical, Inc. Obtains Production Rights for Two Additional Drugs
5. Sanofi-aventis U.S. Announces Increased Access to Drugs for Low Income Patients Through Expanded PAP Programs
6. FDA Puts Black-Box Warning on Bowel-Cleansing Drugs
7. Cancer drugs in the pipeline
8. A new class of anti-inflammatory drugs
9. 2 Diabetes Drugs Double Fracture Risk in Women
10. Two common diabetes drugs double the risk of fractures in women
11. Popular class of diabetes drugs doubles risk of fractures in women
Post Your Comments:
Related Image:
Alzheimer's Drugs Also Treat Behavioral, Psych Problems
(Date:6/25/2016)... ... June 25, 2016 , ... Conventional wisdom preaches the benefits ... terms of the latter, setting the bar too high can result in disappointment, perhaps ... slow progress toward their goal. , Research from reveals that ...
(Date:6/24/2016)... (PRWEB) , ... June 24, 2016 , ... June 19, ... the dangers associated with chronic pain and the benefits of holistic treatments, Serenity ... who are suffering with Sickle Cell Disease. , Sickle Cell Disease (SCD) is a ...
(Date:6/24/2016)... ... 24, 2016 , ... Global law firm Greenberg Traurig, P.A. announced that 20 ... by their peers for this recognition are considered among the top 2 percent of ... honors as members of this year’s Legal Elite Hall of Fame: Miami Shareholders ...
(Date:6/24/2016)... ... June 24, 2016 , ... Topical BioMedics, Inc, makers of Topricin and MyPainAway Pain Relief Products, ... minimum wage raise to $12 an hour by 2020 and then adjusting it yearly to ... value of the minimum wage, assure the wage floor does not erode again, and make ...
(Date:6/24/2016)... ... June 24, 2016 , ... The Haute Beauty Network, ... M. Weintraub as a prominent plastic surgeon and the network’s newest partner. ... the most handsome men, look naturally attractive. Plastic surgery should be invisible.” He ...
Breaking Medicine News(10 mins):
(Date:6/24/2016)... SAN FRANCISCO, Calif. , June 24, 2016 ... GBT ), a biopharmaceutical company developing novel therapeutics ... significant unmet needs, today announced the closing of ... shares of common stock, at the public offering ... shares in the offering were offered by GBT. ...
(Date:6/24/2016)... June 24, 2016 Dehaier Medical Systems Ltd. ... which develops, markets and sells medical devices and wearable ... signed a strategic cooperation agreement with Hongyuan Supply Chain ... Chain") on June 20, 2016, to develop Dehaier,s new ... cooperation agreement, Dehaier will leverage Hongyuan Supply Chain,s sales ...
(Date:6/24/2016)... , June 24, 2016 ... appointment of Dr. Edward Futcher to ... Director, effective June 23, 2016.Dr. Futcher was also ... and Governance Committees.  As a non-executive member of ... expertise and strategic counsel to VolitionRx in connection ...
Breaking Medicine Technology: