Navigation Links
Alzheimer's Drugs Also Treat Behavioral, Psych Problems
Date:12/17/2008

Therapy effective at same dosage used to improve cognitive impairment, study says

WEDNESDAY, Dec. 17 (HealthDay News) -- Drugs used to treat Alzheimer's patients' cognitive symptoms are also a safe and effective therapy for behavioral and psychological symptoms such as aggression, wandering and paranoia, according to U.S. researchers.

They reviewed nine studies that examined the effectiveness of three popular cholinesterase inhibitors in managing Alzheimer's patients' behavioral and psychological symptoms, and found the drugs were effective at the same dosage used to improve cognitive impairment.

The study was published in the December issue of Clinical Interventions in Aging.

About 90 percent of Alzheimer's patients have behavioral and psychological symptoms. Cholinesterase inhibitors boost levels of a brain chemical called acetylcholine, which assists memory, thought and judgment.

"There is a need for safe alternatives to the antipsychotic drugs currently used to manage the behavioral and psychological symptoms of Alzheimer's disease. The results of the studies we analyzed are encouraging and suggestive that cholinesterase inhibitors are safe and effective alternatives," review co-author Dr. Malaz Boustani, an assistant professor of medicine at the Indiana University School of Medicine, said in a university news release.

"However, [cholinesterase inhibitors] are underutilized and typically prescribed for less than three months and for less than 10 percent of patients with Alzheimer's disease. Our findings might provide clinicians with useful data to justify the appropriate use of these medications," said Boustani, a researcher at the IU Center for Aging Research and chief research officer of the Indianapolis Discovery Network for Dementia.

"This class of medications has already been approved the Food and Drug Administration to manage symptoms of Alzheimer's type dementia, although the potential benefits on behavioral symptoms are not frequently identified by many prescribers," study co-author Noll Campbell, a clinical pharmacy specialist in geriatric psychiatry with Wishard Health Services, said in the news release. The use of cholinesterase inhibitors could reduce "the use of more harmful medications that are needed to control [dementia-related] behaviors."

More information

The U.S. National Institute on Aging has more about Alzheimer's medications.



-- Robert Preidt



SOURCE: Indiana University, news release, Dec. 9, 2008


'/>"/>
Copyright©2008 ScoutNews,LLC.
All rights reserved  

Related medicine news :

1. Alzheimers Research Target May Be a Dead End
2. FDA Adds Suicide Warning to Epilepsy Drugs
3. UIC researchers hunting drugs for devastating parasitic disease
4. China Sky One Medical, Inc. Obtains Production Rights for Two Additional Drugs
5. Sanofi-aventis U.S. Announces Increased Access to Drugs for Low Income Patients Through Expanded PAP Programs
6. FDA Puts Black-Box Warning on Bowel-Cleansing Drugs
7. Cancer drugs in the pipeline
8. A new class of anti-inflammatory drugs
9. 2 Diabetes Drugs Double Fracture Risk in Women
10. Two common diabetes drugs double the risk of fractures in women
11. Popular class of diabetes drugs doubles risk of fractures in women
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Alzheimer's Drugs Also Treat Behavioral, Psych Problems
(Date:1/23/2017)... ... January 23, 2017 , ... "ProRandom is a set of camera tools that allow video ... in Final Cut Pro X," said Christina Austin - CEO of Pixel Film Studios. ... of text with video footage. ProRandom works by using a virtual camera to create ...
(Date:1/23/2017)... ... January 23, 2017 , ... ... Society of Anesthesiologists® (ASA®), the Foundation for Anesthesia Education and Research (FAER), ... (AAOS) and the Cigna Foundation, encourages proposals supporting high quality research using ...
(Date:1/23/2017)... ... ... a story of love and redemption, hope and uncertainty as a girl makes her way ... at the Mill” is the creation of published author, Lois Kulp, who was born in ... County on Crow Hill. The inn, the mill and "Post Yokel" are within ...
(Date:1/23/2017)... , ... January 23, 2017 ... ... (SNP) has launched online education programs and resources at seafoodnutrition.org/programs and seafoodnutrition.org/resources ... benefits of a seafood-rich diet. These resources have been developed for use ...
(Date:1/23/2017)... ... ... “Some Infallible Characteristics of Christ”: a fascinating and entrancing novel exploring the gifts ... published author, Rev. Dr. Robert W. Thomas, the third of seven siblings. He was ... a pastor for over fifteen years. He is a graduate of N.C. College of ...
Breaking Medicine News(10 mins):
(Date:1/23/2017)... janvier 2017  ResMed (NYSE : RMD), BMC (Pékin, Chine) ... annoncé aujourd,hui qu,ils se sont mis d,accord sur le ... parties. BMC et 3B seront autorisés à vendre leurs ... ResMed, et ResMed effectuera le paiement de la décision ... litige de Floride entre les deux parties. Le règlement ...
(Date:1/23/2017)... 2017 NeuroVive Pharmaceutical AB (Nasdaq Stockholm: ... preclinical collaboration agreement with the Children,s Hospital of ... M.D., a US key opinion leader in the mitochondrial medicine ... ... from NeuroVive,s research program, NVP015, in certain experimental disease models. ...
(Date:1/22/2017)... DAVOS, Switzerland and ABU DHABI , ... leaders from the US ... , Hospital of the Future , at ... in the hospital of the future will be driven by big data and ... better," according to the panel of experts that discussed the ,Hospital of the ...
Breaking Medicine Technology: