Navigation Links
Alzheimer's Disease Risk Factors May Be Gender-Specific

French study finds depression, stroke key factors in progression toward dementia

THURSDAY, May 1 (HealthDay News) -- Depression in women and stroke in men are critical factors in the development of Alzheimer's disease, French researchers report.

They analyzed data from almost 7,000 people over the age of 65 in three French cities. None of them had dementia, but about 40 percent had mild cognitive impairment at the start of the study.

They were assessed two and four years later. Of those with mild cognitive impairment at the start of the study, just over 6.5 percent developed dementia over the next four years, about half had no change, and about one-third regained normal levels of cognitive ability.

People with depression, those taking anticholinergic drugs (which influence chemical signaling in the brain), and those with a variation in the ApoE gene (a known risk factor for dementia) were more likely to progress from mild cognitive impairment to dementia.

The researchers also found that risk factors varied according to gender. Men with mild cognitive impairment were more likely to be overweight, diabetic and to have had a stroke. Men who'd suffered a stroke were almost three times more likely to progress from mild cognitive impairment to dementia.

Women with mild cognitive impairment were more likely to be in poorer general health, disabled, suffering from insomnia, and to have a poor support network. Women with depression were twice as likely to progress from mild cognitive impairment to dementia, while women unable to perform routine daily tasks (which would allow them to live without assistance) were 3.5 times more likely to progress to dementia.

Stroke was not a risk factor for women, even though both women and men had similar rates of stroke.

The study was published online in the Journal of Neurology Neurosurgery & Psychiatry.

More information

The U.S. National Institute on Aging has more about Alzheimer's disease.

-- Robert Preidt

SOURCE: BMJ Specialist Journals, news release, May 1, 2008

Copyright©2008 ScoutNews,LLC.
All rights reserved

Related medicine news :

1. Alzheimers Research Target May Be a Dead End
2. Prozac Reduces Disease Activity in MS Patients
3. Salk study links diabetes and Alzheimers disease
4. High rate of complicated idiopathic gallstone disease in pediatric patients
5. How to manage Chinese obese children with non-alcoholic fatty liver disease?
6. Promising early evidence of the superior benefits of drug therapy for diabetic eye disease
7. New treatment could reduce chronic lung disease in premature babies
8. Hundreds of Heart Disease and Stroke Survivors Urge Congress to Step Up the Fight Against the Nations No. 1 Killer
9. Vermillion to Host Live Roundtable Discussion With Lead Investigator of its Peripheral Artery Disease Diagnostic Test Program
10. Transitioning patients with pediatric disease to adulthood
11. Investigators unveil new drug discovery tool for Alzheimers disease
Post Your Comments:
(Date:11/25/2015)... ... November 25, 2015 , ... On November 23rd 2015 Cozy ... personal heating products business. Cozy Products explains what this means for business moving ... well with the Cozy Products business model: to sell personal heaters that reduce energy ...
(Date:11/25/2015)... ... November 25, 2015 , ... ... of music, friendships, and learning in its 65th Anniversary Brillianteen Revue, scheduled for ... , For 65 years, Brillianteen has been a treasured tradition for ...
(Date:11/25/2015)... Missouri (PRWEB) , ... November 25, 2015 , ... ... HEAL, will provide scholarships for people struggling with eating disorders as a result ... from the second annual event, held at Fox Run Golf Club in Eureka, ...
(Date:11/25/2015)... , ... November 25, 2015 , ... ... of philanthropic seniors, is resulting in a way for homeless people to have ... Schaumburg have launched a new initiative whereby they are repurposing plastic bags into ...
(Date:11/25/2015)... (PRWEB) , ... November 25, 2015 , ... Students and ... were awarded to winners of the Create Real Impact awards. California Casualty ... to help stem the tide of distracted and reckless driving, the number one killer ...
Breaking Medicine News(10 mins):
(Date:11/25/2015)... DUBLIN , Nov. 25, 2015 Research ... of the "Membranes Market - Global Forecast to ... Asia-Pacific , accounting for 37.21% of the ... Asia-Pacific region is projected to ... This growth has been attributed primarily to the fast ...
(Date:11/25/2015)... 25, 2015 ... of the  "Global Drug Device Combination ... their offering.  --> ... the  "Global Drug Device Combination Products ... offering.  --> Research and ...
(Date:11/24/2015)... -- WuXi PharmaTech (Cayman) Inc. ("WuXi" or the "Company") ... and technology platform company serving the pharmaceutical, biotechnology, and ... and the United States ... of shareholders held today, the Company,s shareholders voted in ... previously announced agreement and plan of merger (the "Merger ...
Breaking Medicine Technology: