Navigation Links
Alternative to antibiotics
Date:10/1/2013

As they destroy bacteria very efficiently, plasmas constitute an alternative to chemical disinfectants and potentially to antibiotics, as well. How they achieve this effect has been investigated by biologists, plasma physicists and chemists at the Ruhr-Universitt (RUB). Cold atmospheric-pressure plasmas attack the prokaryote's cell envelope, proteins and DNA. "This is too great a challenge for the repair mechanisms and the stress response systems of bacteria," says Junior Professor Dr Julia Bandow, Head of the Junior Research Group Microbial Antibiotic Research at the RUB. "In order to develop plasmas for specific applications, for example for treating chronic wounds or for root canal disinfection, it is important to understand how they affect cells. Thus, undesirable side effects may be avoided right from the start." The team reports in the "Journal of the Royal Society Interface".

Plasmas affect cell envelope, DNA and proteins

Depending on their specific composition, plasmas may contain different components, for example ions, radicals or light in the ultraviolet spectrum, so-called UV photons. Until now, scientists have not understood which components of the complex mixture contribute to which extent to the antibacterial effect. Julia Bandow's team has analysed the effect of UV photons and reactive particles, namely radicals and ozone, on both the cellular level and on the level of single biomolecules, namely DNA and proteins. On the cellular level, the reactive particles alone were most effective: they destroyed the cell envelope. On the molecular level, both plasma components were effective. Both UV radiation and reactive particles damaged the DNA; in addition, the reactive particles inactivated proteins.

No effective antibiotics in ten years' time?

Atmospheric-pressure plasmas are already being used as surgical tools, for example in nasal and intestinal polyp extraction. Their properties as disinfectants may also be of interest with regard to medical applications. "In ten years, bacteria might have developed resistance against all antibiotics that are available to us today," says Julia Bandow. Without antibiotics, surgery would become impossible due to high infection rates.


'/>"/>

Contact: Dr. Julia Bandow
Julia.Bandow@rub.de
49-234-322-3102
Ruhr-University Bochum
Source:Eurekalert

Related medicine news :

1. Procedure gives patients with A-fib who cant take blood thinners alternative to reduce stroke
2. Study Supports Value of Sigmoidoscopy, an Alternative to Colonoscopy
3. Approval of Safer Alternative to Pradaxa Delayed by FDA
4. Smokers Drop Pricey Cigarettes for Cheaper Alternatives: CDC
5. Alternatives to Medicares fee-for-service payment system examined
6. NHS should replace traditional autopsies with non-invasive alternative
7. Complementary and alternative therapy improved lives of arthritis patients
8. Water Workouts a Great Alternative: Study
9. Controversial Alternative Heart Treatment Shows Hint of Benefit
10. GW researcher receives $4.1 million grant to find alternative treatment for kidney stones
11. Potential new technique for anticancer radiotherapy could provide alternative to brachytherapy
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:4/29/2016)... ... April 29, 2016 , ... ... author of best seller "LOVE, MEDICINE and MIRACLES") addresses touchy topics related to ... and podcasted thereafter . Dr. Bernie Siegel, author of a plethora of ...
(Date:4/29/2016)... , ... April 29, 2016 , ... ... reveals that infants born with severe congenital diaphragmatic hernia have better survival rates ... with congenital diaphragmatic hernia (CDH)—a condition where the diaphragm fails to form completely, ...
(Date:4/29/2016)... ... April 29, 2016 , ... World Patent Marketing , ... exercise invention which aids in proper muscle development. , "The Gym & Exercise ... Director of World Patent Marketing. "Globalization has threatened the future growth of the ...
(Date:4/29/2016)... ... ... New York City based oral and maxillofacial surgeon Dr. Majid Jamali is an ... obstructive sleep apnea. Dr. Jamali is proud to offer this permanent solution to patients who ... both jaw bones. This surgery is performed to correct the alignment of the jaw. It ...
(Date:4/29/2016)... ... 29, 2016 , ... Innovations with Ed Begley Jr., announced ... airing third quarter 2016 via Discovery Channel. Dates and show times TBA. , ... located in Greenwood, Wisconsin applies product research and development and continuous technological improvements ...
Breaking Medicine News(10 mins):
(Date:4/27/2016)... 2016 The global  gamma ... billion by 2022, according to a new report ... towards a healthy lifestyle is expected to drive ...      (Logo: http://photos.prnewswire.com/prnh/20150105/723757 ) , ... health treatment expenditure has urged consumers to switch ...
(Date:4/26/2016)... FLINT, Mich. , April 26, 2016 ... the promotion of Jennifer Hagerman , Pharm D., ... In her growing role at Diplomat, Hagerman will continue ... of the company that delivers custom education and training ... to the specialty pharmacy industry. Diplomat University also houses ...
(Date:4/26/2016)... 26, 2016 US demand for infection ... 4.9 percent annually to $27.6 billion in 2020.  ... to decrease rates of healthcare-associated infections (HAIs) will ... and services.  Although declining, the overall rate of ... levels set by the CDC.  Recent statistics indicate ...
Breaking Medicine Technology: