Navigation Links
Alternative to antibiotics
Date:10/1/2013

As they destroy bacteria very efficiently, plasmas constitute an alternative to chemical disinfectants and potentially to antibiotics, as well. How they achieve this effect has been investigated by biologists, plasma physicists and chemists at the Ruhr-Universitt (RUB). Cold atmospheric-pressure plasmas attack the prokaryote's cell envelope, proteins and DNA. "This is too great a challenge for the repair mechanisms and the stress response systems of bacteria," says Junior Professor Dr Julia Bandow, Head of the Junior Research Group Microbial Antibiotic Research at the RUB. "In order to develop plasmas for specific applications, for example for treating chronic wounds or for root canal disinfection, it is important to understand how they affect cells. Thus, undesirable side effects may be avoided right from the start." The team reports in the "Journal of the Royal Society Interface".

Plasmas affect cell envelope, DNA and proteins

Depending on their specific composition, plasmas may contain different components, for example ions, radicals or light in the ultraviolet spectrum, so-called UV photons. Until now, scientists have not understood which components of the complex mixture contribute to which extent to the antibacterial effect. Julia Bandow's team has analysed the effect of UV photons and reactive particles, namely radicals and ozone, on both the cellular level and on the level of single biomolecules, namely DNA and proteins. On the cellular level, the reactive particles alone were most effective: they destroyed the cell envelope. On the molecular level, both plasma components were effective. Both UV radiation and reactive particles damaged the DNA; in addition, the reactive particles inactivated proteins.

No effective antibiotics in ten years' time?

Atmospheric-pressure plasmas are already being used as surgical tools, for example in nasal and intestinal polyp extraction. Their properties as disinfectants may also be of interest with regard to medical applications. "In ten years, bacteria might have developed resistance against all antibiotics that are available to us today," says Julia Bandow. Without antibiotics, surgery would become impossible due to high infection rates.


'/>"/>

Contact: Dr. Julia Bandow
Julia.Bandow@rub.de
49-234-322-3102
Ruhr-University Bochum
Source:Eurekalert

Related medicine news :

1. Procedure gives patients with A-fib who cant take blood thinners alternative to reduce stroke
2. Study Supports Value of Sigmoidoscopy, an Alternative to Colonoscopy
3. Approval of Safer Alternative to Pradaxa Delayed by FDA
4. Smokers Drop Pricey Cigarettes for Cheaper Alternatives: CDC
5. Alternatives to Medicares fee-for-service payment system examined
6. NHS should replace traditional autopsies with non-invasive alternative
7. Complementary and alternative therapy improved lives of arthritis patients
8. Water Workouts a Great Alternative: Study
9. Controversial Alternative Heart Treatment Shows Hint of Benefit
10. GW researcher receives $4.1 million grant to find alternative treatment for kidney stones
11. Potential new technique for anticancer radiotherapy could provide alternative to brachytherapy
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:10/12/2017)... ... October 12, 2017 , ... The American College of Medical Informatics (ACMI) ... FACMI, during the Opening Session of AMIA’s Annual Symposium in Washington, D.C. AMIA’s ... Morris F. Collen, a pioneer in the field of medical informatics, this prestigious award ...
(Date:10/12/2017)... ANGELES (PRWEB) , ... October 12, 2017 , ... ... Parsa Mohebi Hair Restoration, has recently contributed a medical article to the newly ... on cosmetictown.com. Dr. Mohebi’s article spotlights the hair transplant procedure known as ...
(Date:10/12/2017)... , ... October 12, 2017 , ... On Saturday, October ... treadmill relay – Miles by Moonlight to raise money for the American Heart Association ... more. , Teams will work together to keep their treadmills moving for 5 ...
(Date:10/12/2017)... ... October 12, 2017 , ... ... property taxes a year. In some states—like New York, New Jersey, Massachusetts, Texas, ... many overseas retirement havens have extremely low property-tax rates, which contributes to the ...
(Date:10/12/2017)... ... October 12, 2017 , ... Vodori, ... Flow promotional review platform at the Promotional Review Committee Compliance and Best ... marketers streamline the medical, legal, and regulatory review (MLR) process – which ...
Breaking Medicine News(10 mins):
(Date:9/25/2017)... Sept. 25, 2017  EpiVax, Inc., a leader ... and immune-engineering today announced the launch of EpiVax ... of personalized therapeutic cancer vaccines. EpiVax has provided ... access to enabling technologies to the new precision ... lead EpiVax Oncology as Chief Executive Officer. Gad ...
(Date:9/19/2017)... 2017   ZirMed Inc ., a recognized leader in ... it has been ranked #1 by its users for the ... 2017 User Survey. ZirMed was recognized as the top-ranked end-to-end ... medical centers over 200 beds and holds one of the ... survey history. ...
(Date:9/12/2017)... Sept. 12, 2017  Consumer reviews on the independent review site ... the number one company for hearing aids, ranking it higher than ... brands. ... #1 by Consumers For Hearing Aids ... Hearing is an online store that provides high performance, state-of-the-art, German-engineered ...
Breaking Medicine Technology: