Navigation Links
AlphaRx Presents Positive Preclinical Data on Zysolin(TM) Inhalable Nanoparticles at Controlled Release Society Annual Meeting
Date:7/23/2009

MARKHAM, ON, July 23 /PRNewswire-FirstCall/ - AlphaRx, Inc. (OTCBB: ALRX) announced positive preclinical results which demonstrated that an inhaled tobramycin nanoparticle (Zysolin(TM)) formulation was a more effective treatment in animal models of acute Pseudomonas aeruginosa pneumonia when compared to inhaled and injected conventional tobramycin solutions. The data was presented recently in an oral podium session at the 36th Annual Meeting and Exposition of the Controlled Release Society in Copenhagen, Denmark.

"These are very encouraging results, as they suggest that Zysolin(TM) employed in this route of administration may be more effective, providing significant advantages over conventional drug formulations," stated Joseph Schwarz, Ph.D., Chief Scientist of AlphaRx. "We believe that building on this data, additional research will lead us toward the development of a drug that targets and eradicates intracellular pathogens, which to date, have proven to be very difficult to treat clinically."

The study results demonstrate that Zysolin(TM) is significantly efficacious in acute pneumonia animal models induced by gram negative pathogens including P. aeruginosa. In these lethality-based studies, Zysolin(TM) consistently increased survival rate to 50% over a Tobramycin treatment group, wherein all untreated animals died within 24 hours after infection. P. aeruginosa is one of the most common and lethal pathogens responsible for ventilator-associated pneumonia in intubated patients, being directly responsible for death rates approaching 40%. This data suggests that the nanoparticulate formulation of Zysolin(TM) may utilize a unique mechanism of action differentiating it from conventional formulations, enhancing antimicrobial activity against gram negative pathogens. Zysolin(TM) has the potential to be a first-in-class anti-infective nanomedicine.

The Controlled Release Society (CRS) is an international organization consisting of 3,000 mem
'/>"/>

SOURCE AlphaRx Inc.
Copyright©2009 PR Newswire.
All rights reserved

Page: 1 2 3

Related medicine news :

1. AlphaRx Unveils its China Strategy
2. AlphaRx Reports Positive Preclinical Data on GAI-122 Against Liver Disease
3. AlphaRx and Gaia BioPharma Report Positive Efficacy Results in a Pre-Clinical Trial of GAI-122 Injectable Nano-emulsion for Post-operative Delirium
4. AlphaRx Shareholder Update
5. AlphaRx and Gaia BioPharma Provide GAI-122 Development Update
6. AlphaRx Signs Cooperative Research and Development Agreement with US Army
7. AlphaRx Provides Corporate and Development Update
8. AlphaRxs Indaflex(TM) Continues its Clinical Development
9. AlphaRx CEO Accumulates More Company Shares
10. AlphaRx Officers and Directors To Exercise Options, Warrants and Retain Shares
11. AlphaRx Announces Debt Conversion
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:8/20/2014)... New York, NY (PRWEB) August 20, 2014 ... Trailblazer Awards. PM360, a leading health-marketing industry trade magazine, ... in 2009, the Trailblazer Awards are given to outstanding ... industry has to offer. , “We are proud ... to our call to entries with double the number ...
(Date:8/20/2014)... A Missouri federal judge has remanded a lawsuit filed ... GranuFlo and NaturaLyte to the City of St. Louis Circuit ... The judge rejected an assertion by the defendants that the ... et al. v. Fresenius Medical Care North America Inc., et ... the manufacturer of the dialysis products GranuFlo and NaturaLyte. In ...
(Date:8/20/2014)... "I decided that there needed to be a ... without the hassles associated with using conventional oral devices," ... DR. GATES ORAL-HYGIENE TOOL provides an easy way to ... oral hygiene and fresh breath, and it eliminates the ... eco-friendly and easy to use, the device is producible ...
(Date:8/20/2014)... Manchester and Auckland suggest that both major forms of diabetes ... findings, published today in the FASEB Journal (20 ... type-2 diabetes are both caused by the formation of toxic ... results, based on 20 years, work in New Zealand, suggest ... and potentially reversed by medicines that stop amylin forming these ...
(Date:8/20/2014)... August 20, 2014 According to ... by technology (Electrochromics, SPD, Liquid Crystal, Microblinds, Thermographic ... generation, Electronics & others), by geography - Global ... the value of Smart glass market was worth ... reach $5814 Million by 2020, at an estimated ...
Breaking Medicine News(10 mins):Health News:PM360 Announces 2014 Trailblazer Award Finalists 2Health News:PM360 Announces 2014 Trailblazer Award Finalists 3Health News:PM360 Announces 2014 Trailblazer Award Finalists 4Health News:PM360 Announces 2014 Trailblazer Award Finalists 5Health News:PM360 Announces 2014 Trailblazer Award Finalists 6Health News:PM360 Announces 2014 Trailblazer Award Finalists 7Health News:PM360 Announces 2014 Trailblazer Award Finalists 8Health News:GranuFlo/NaturaLyte Case Remanded to State Court By Missouri Federal Judge, Baron and Budd Reports 2Health News:Scientists show type-1 and type-2 diabetes are caused by same underlying mechanism 2Health News:Smart Glass Market by Technology Worth $5814 Million by 2020 – New Report by MarketsandMarkets 2Health News:Smart Glass Market by Technology Worth $5814 Million by 2020 – New Report by MarketsandMarkets 3Health News:Smart Glass Market by Technology Worth $5814 Million by 2020 – New Report by MarketsandMarkets 4Health News:Smart Glass Market by Technology Worth $5814 Million by 2020 – New Report by MarketsandMarkets 5
... flu scare had prohibited the hunting and killing of any ... that the prohibition would continue// till Turkey has completely worked ... Turkey has seen two deaths due to bird flu. ... and also asked the support from the people to help ...
... people in Britain have increased the alcohol intake and liver cirrhosis ... deaths due to liver cirrhosis developed by drinking alcohol have doubled ... rise in the death rates due to liver cirrhosis. ... drinking associated diseases have been on the rise. ,In ...
... the journal Nature says that a team of Australian researchers ... Institute in Melbourne have successfully // isolated ... that could hold the key to future breast cancer treatments ... recurrences of breast cancer are triggered by a group of ...
... effects of HIV/AIDS. According to a report by NPR titled ... troubled family ties. ,Most Family structures ... // young Ugandan adults have succumbed to aids-related complexities in ... the Aged Association, is of the opinion that family structures ...
... health official of china it is supposed that China is lacking ... a new wave of HIV/Aids infections. The problem is more severe ... able to control it," Mr Wu a top Aids official at ... have seen some of the worst-hit areas with your own eyes ...
... radiation and gold nanoparticles can help in slowing down ... conducted by scientists from Spain and Chile. The healthy ... affected by this. According to their study, to be ... technique, a type of molecular surgery, has the potential ...
Cached Medicine News:Health News:Rise in the death rates among the British due to alcohol intake. 2
(Date:8/20/2014)... , Aug. 20, 2014   Ventana Medical ...  Group, today announced that its VENTANA System for ... in the European Union for routine pathology, including ... consisting of VENTANA Virtuoso software coupled with either ... HT slide scanner, provides automated digital slide creation, ...
(Date:8/20/2014)... CITY , Aug. 20, 2014 ApolloDx™ ... mobile diagnostic platform during a special event at the ... , on September 5, 2014. The event, which ... on the ApolloDx website, www.apollodx.com .    ... diagnostic testing," said Jared Bauer , Co-Founder and ...
(Date:8/20/2014)... DIEGO , Aug. 20, 2014 Trovagene, ... diagnostics, announced today that results from two clinical studies ... conference for the Company,s urine-based diagnostic test for the ... The IPV conference is scheduled to take place in ... to 25 th . Additionally, a new U.S. ...
Breaking Medicine Technology:Full digitization of the anatomic pathology lab is here with the VENTANA System for Primary Diagnosis 2Full digitization of the anatomic pathology lab is here with the VENTANA System for Primary Diagnosis 3Trovagene Provides Update on Its Urine-Based HPV Test 2Trovagene Provides Update on Its Urine-Based HPV Test 3
The focus of HandEchart Professional is to offer a practical and basic electronic patient record keeping system that anyone can learn in minutes....
Archimedes is an innovative specialty calculator. Forget having to remember complicated formulas, just enter the values and out come the results....
A handy, quick reference for physicians, nurses, and other health care providers treating cancer patients....
A handy quick-reference tool for busy residents and clinicians with key facts and points essential for day-to-day patient care....
Medicine Products: