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Allergies Linked to Lower Brain Cancer Rate in Study
Date:2/7/2011

By Randy Dotinga
HealthDay Reporter

MONDAY, Feb. 7 (HealthDay News) -- If you suffer from allergies, take heart: Researchers say you may be less likely to develop a tough-to-treat brain cancer, possibly because your immune system is on high alert.

It's not clear how this knowledge might improve prevention or treatment of brain cancer, but the study's lead author said the findings pave the way for further research.

"We need to do more studies to really get at that underlying mechanism. Then we might be able to do things that would influence people who might have a higher risk or may have a family history," said Bridget J. McCarthy, a research associate professor of epidemiology at the University of Illinois at Chicago.

The lesions studied are known as gliomas, the most common type of adult brain tumor. They account for more than half of the 18,000-plus malignant brain tumors diagnosed in the United States every year, according to the U.S. National Cancer Institute.

Gliomas -- which led to the death of Sen. Edward Kennedy -- often cause death within months, despite surgery or treatment with chemotherapy or radiation.

Researchers have published conflicting studies about whether people with allergies and autoimmune disorders (which cause the immune system to attack the body) have a lower risk of developing the tumors, McCarthy said. "We wanted to look at the spectrum and see if we found the association with any type of allergy," McCarthy explained.

In the study, published Feb. 7 in the journal Cancer Epidemiology, Biomarkers & Prevention, McCarthy and colleagues examined surveys filled out by 419 patients with gliomas and 612 cancer-free patients from North Carolina and Illinois. All of the patients were asked if they had doctor-diagnosed allergies -- seasonal, medication, food, pet or any other -- and whether they took antihistamines.

The researchers found that patients with b
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