Navigation Links
Allergic-like reactions occur in premedicated patients
Date:2/8/2008

Allergic-like reactions can occur in patients (both children and adults) when given gadolinium containing contrast agents, even if they have been pre-medicated with corticosteroids and antihistamines, according to a recent study conducted by researchers at the University of Michigan Health Systems in Ann Arbor.

We pre-medicate patients at our institution who have a history of prior allergic-like reaction to gadolinium-containing contrast agents, said Jonathan R. Dillman, MD, lead author of the study. Pre-medication is sometimes also considered in patients who have a history of prior severe allergic-like reaction to another substance (including iodinated contrast material), said Dr. Dillman. While we know from previous studies that allergic-like reactions may occur following pre-medication in the setting of repeat iodinated contrast material injections (the so-called breakthrough reaction), we were uncertain if this phenomenon also occurred in the setting of repeat gadolinium-containing contrast material administration, he said.

The researchers reviewed contrast material reaction forms from the institutions department of radiology over a five-year period. According to the study, eight patients experienced nine allergic-like reactions (one patient experienced two breakthrough reactions) after being administered a gadolinium-containing contrast agent despite being pre-medicated. Of these reactions, six were mild and three were moderate. There were no severe or fatal breakthrough reactions. All patients who experienced breakthrough reactions had a history of allergic-like reactions to either gadolinium or iodine containing contrast media.

While we believe that pre-medication likely decreases an individuals risk of allergic-like reaction to gadolinium-containing contrast material, our study concludes that breakthrough reactions do occur. Radiologists, therefore, must be available to treat an allergic-like reaction following gadolinium-containing contrast material administration, even when a patient has been pre-medicated with corticosteroids and antihistamines, said Dr. Dillman.


'/>"/>

Contact: Necoya Tyson
necoya@arrs.org
703-858-4304
American Roentgen Ray Society
Source:Eurekalert

Related medicine news :

1. London School of Hygiene to play key role in global collaboration on adverse drug reactions
2. DOCTORS OPPOSE MARYLAND VACCINE ROUNDUP: Expect Dangerous Reactions When Children Are Treated Like Cattle
3. MDs reactions to pharma marketing influenced by brand, side effects: Management Insights
4. Allergic reactions to gadolinium-based contrast agents are rare, study finds
5. Smoking and depression often co-occur in new mothers
6. Mental illness and drug addiction may co-occur due to disturbance in part of the brain
7. Carnegie Mellon study identifies where thoughts of familiar objects occur inside the human brain
8. Sickle Cell Disease Pain Can Occur Daily and Is Much More Severe Than Previously Thought
9. Fluctuating eye pressure associated with visual field deterioration in glaucoma patients
10. Comparison of obstetric outcomes between on-call and patients own obstetricians
11. Vision restoration therapy shown to improve brain activity in brain injured patients
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:2/27/2017)... ... February 27, 2017 , ... This webinar , sponsored ... a tool to characterize particle size distributions in the field of geoscience and ... novel scientific findings. It describes methods of optimized and standardized sample collection, preparation ...
(Date:2/27/2017)... ... February 27, 2017 , ... POUGHKEEPSIE, N. Y. – Peer-reviewed guidelines from ... scientific studies, the Center for Disease Control ( CDC ) and Infectious Diseases Society ... B. Liegner, M.D. has compiled into a single volume a compelling argument that the ...
(Date:2/27/2017)... ... February 27, 2017 , ... Sunshine Coast Health Centre ... Columbia, Canada, at https://www.sunshinecoasthealthcentre.ca/ , is proud to announce the addition of ... showcases the Centre's commitment to innovation in drug rehab and alcohol treatment strategies ...
(Date:2/27/2017)... ... February 27, 2017 , ... ... and environs, is proud to announce an upgrade to the company's Yelp listing. ... Yelp page on topics as diverse as Platelet Rich Plasma (PRP) therapy, hair ...
(Date:2/26/2017)... , ... February 25, 2017 , ... The February 13, ... heightened awareness and concern over nerve agents and the deadly use of chemical weapons. ... nervous system and how even small doses can be lethal. , Jay Jagannathan, M.D., ...
Breaking Medicine News(10 mins):
(Date:2/27/2017)...  Infinity Pharmaceuticals, Inc. (NASDAQ: INFI ) ... th Annual Healthcare Conference on Monday, March 6, ... MA. A live webcast of Infinity,s presentation ... website at www.infi.com , and will be available ... Infinity,Infinity is an innovative biopharmaceutical company dedicated to advancing ...
(Date:2/27/2017)... Inc. (NASDAQ: IPXL ) today announced that it plans to ... Raymond James and Associates, 38 th Annual Institutional Investors Conference ... FL. Cowen and Company 37 th ... in Boston, MA. Barclays Global ... Miami, FL. Individuals may listen to ...
(Date:2/27/2017)... -- A recent research report published by Grand View ... expected to reach a value of $55.8 billion by 2025. Earlier ... states have legalized marijuana for medical uses. In 2016, states such ... North Dakota , Ohio ... drug in medical applications such as chemotherapies and pain management. The ...
Breaking Medicine Technology: