Navigation Links
Allergic-like reactions occur in premedicated patients
Date:2/8/2008

Allergic-like reactions can occur in patients (both children and adults) when given gadolinium containing contrast agents, even if they have been pre-medicated with corticosteroids and antihistamines, according to a recent study conducted by researchers at the University of Michigan Health Systems in Ann Arbor.

We pre-medicate patients at our institution who have a history of prior allergic-like reaction to gadolinium-containing contrast agents, said Jonathan R. Dillman, MD, lead author of the study. Pre-medication is sometimes also considered in patients who have a history of prior severe allergic-like reaction to another substance (including iodinated contrast material), said Dr. Dillman. While we know from previous studies that allergic-like reactions may occur following pre-medication in the setting of repeat iodinated contrast material injections (the so-called breakthrough reaction), we were uncertain if this phenomenon also occurred in the setting of repeat gadolinium-containing contrast material administration, he said.

The researchers reviewed contrast material reaction forms from the institutions department of radiology over a five-year period. According to the study, eight patients experienced nine allergic-like reactions (one patient experienced two breakthrough reactions) after being administered a gadolinium-containing contrast agent despite being pre-medicated. Of these reactions, six were mild and three were moderate. There were no severe or fatal breakthrough reactions. All patients who experienced breakthrough reactions had a history of allergic-like reactions to either gadolinium or iodine containing contrast media.

While we believe that pre-medication likely decreases an individuals risk of allergic-like reaction to gadolinium-containing contrast material, our study concludes that breakthrough reactions do occur. Radiologists, therefore, must be available to treat an allergic-like reaction following gadolinium-containing contrast material administration, even when a patient has been pre-medicated with corticosteroids and antihistamines, said Dr. Dillman.


'/>"/>

Contact: Necoya Tyson
necoya@arrs.org
703-858-4304
American Roentgen Ray Society
Source:Eurekalert

Related medicine news :

1. London School of Hygiene to play key role in global collaboration on adverse drug reactions
2. DOCTORS OPPOSE MARYLAND VACCINE ROUNDUP: Expect Dangerous Reactions When Children Are Treated Like Cattle
3. MDs reactions to pharma marketing influenced by brand, side effects: Management Insights
4. Allergic reactions to gadolinium-based contrast agents are rare, study finds
5. Smoking and depression often co-occur in new mothers
6. Mental illness and drug addiction may co-occur due to disturbance in part of the brain
7. Carnegie Mellon study identifies where thoughts of familiar objects occur inside the human brain
8. Sickle Cell Disease Pain Can Occur Daily and Is Much More Severe Than Previously Thought
9. Fluctuating eye pressure associated with visual field deterioration in glaucoma patients
10. Comparison of obstetric outcomes between on-call and patients own obstetricians
11. Vision restoration therapy shown to improve brain activity in brain injured patients
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:4/28/2017)... ... April 28, 2017 , ... Datta ... M.D. has joined the revolutionary endoscopic practice under Dr. Datta. Patel is a ... Pain Medicine. The patented, revolutionary eDiscSculpt Technique created and used by Datta Endoscopic ...
(Date:4/28/2017)... ... April 28, 2017 , ... People are starting to ... “Wearing a hearing aid doesn’t have the stigma it had when great-grandpa wore his ... of Greater Boston, in a NALA North American Speaker Series (NASS) segment. ...
(Date:4/28/2017)... ... April 28, 2017 , ... ... the Brooke Grove Foundation implement a Microsoft Dynamics GP solution that integrates to ... ERP expert that specializes in long-term care, Brooke Grove now has the capability ...
(Date:4/28/2017)... ... 2017 , ... Christie Medical Holdings, Inc. , with its market-leading ... Medical Inc. , a leader in infusion therapy and pain management. , Intravenous ... percent of hospital patients receiving a peripheral IV catheter as part of their treatment ...
(Date:4/27/2017)... ... April 27, 2017 , ... The American Brain Foundation ... Leadership in Neurology Award (PLINA). The couple joins a prestigious list of past ... Walter Mondale, actor Michael J. Fox and former U.S. Attorney General Janet Reno. ...
Breaking Medicine News(10 mins):
(Date:4/20/2017)... , April 20, 2017 Research and ... Pharmaceutical Contract Manufacturing Services Market Analysis By Service (Manufacturing, Research), ... Forecasts, 2014 - 2025" report to their offering. ... The Latin American pharmaceutical ... billion by 2025 Low drug registration cost in ...
(Date:4/19/2017)... The Mobile X-Ray product segment is the most ... the forecast period Mobile X-Ray segment is the ... X-Ray devices market, which is estimated to be valued at ... CAGR of 7% over the forecast period. Mobile X-Ray segment ... US$ 100 Mn in 2017 over 2016. The segment,s revenue ...
(Date:4/19/2017)... Global Prostate Cancer Therapeutics Market: Overview ... cancer therapeutics market analyzes the current and future ... prostate cancer, launch of promising emerging therapies, as ... drugs & therapeutic biological products, and high growth ... side effects are some of the drivers expected ...
Breaking Medicine Technology: