Navigation Links
Allegheny Health Network Team Develops Biomarker for Early Detection of Esophageal Cancer
Date:8/6/2014

l cancer; for identifying and selecting targets for blood testing using a global proteomics profiling platform. The candidate biomarkers were then tested in blood samples from patients with non-Barrett’s esophagus GERD and esophageal cancer. The findings were validated in an independent but similar cohort assembled at Allegheny Health Network and Roswell Park Cancer Institute in Buffalo.

Out of 3,777 identified tissue proteins, five were shown to have significantly elevated levels in blood of patients with esophageal cancer, as compared to those with non-Barrett’s esophagus GERD, and on mathematical modeling four of those five were shown to have predictive value.

Potential future uses for the protein biomarker assay include screening high-risk patients such as those with obesity and GERD, monitoring disease progression from Barrett’s esophagus to high-risk dysplasia to esophageal cancer, tracking a patient’s response to therapy and enabling therapy tailored to a patient’s individual disease biology and detecting recurrence prior to clinical imaging.

“Dr. Jobe’s research shows the value of our approach to working collaboratively and across the full spectrum of disease,” said David Parda, MD, System Chair, Allegheny Health Network Cancer Institute. “This tour de force research integrates clinical work and advanced biology/informatics to improve prevention, treatment, prognostic and predictive capabilities.”

Researchers from the Academic Medical Center in Amsterdam also participated in the study.

Read the full story at http://www.prweb.com/releases/2014/08/prweb12074625.htm.


'/>"/>
Source: PRWeb
Copyright©2014 Vocus, Inc.
All rights reserved

Page: 1 2 3

Related medicine news :

1. Study by Allegheny General Hospital Physicians Shows Oral Immunotherapy is a Safe, Effective Alternative to Allergy Shots for Ragweed Sufferers
2. West Penn Allegheny Health System is First in Pennsylvania to Perform Groundbreaking Minimally-Invasive Procedure for Swallowing Disorder
3. West Penn Allegheny Health System Physicians Pinpoint Gastroesophageal Reflux Disease (GERD) as a Factor That May Cause Chronic Cough
4. Allegheny Health Network Allergist Opposes OTC Sales of Corticosteroids in FDA Testimony, Citing Safety Concerns
5. Allegheny Health Network Becomes Official Medical Provider for Robert Morris University Athletic Program
6. Allegheny Health Network’s LifeFlight Marks 35th Year
7. Allegheny Health Network Partners with Region’s EMS Providers to Advance Treatment of Heart Attack Patients
8. Allegheny General Hospital Streamlines Testing for Liver Transplant Patients with Advanced Cardiac MRI
9. Allegheny Health Network Psychologist among Panelists at Senate Staff Briefing In Support of Legislation to Help Patients with Mental Health, Addiction Disorders
10. Four Allegheny Health Network Hospitals Named High Performers by U.S. News
11. Leading West Suburban OBGYN Practice, Premier Women’s Health, Joins Allegheny Health Network
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:12/25/2014)... Dallas, TX (PRWEB) December 26, 2014 ... and Market Analysis to 2023” focuses on the ... commercial opportunities in the colorectal cancer market. Stivarga ... treatment of colon or rectal cancer. Boehringer Ingelheim ... inhibitor, for the treatment of refractory CRC in ...
(Date:12/25/2014)... Recently, Dylan Queen, a famous online company ... collection of discounted prom dresses, most of which are ... of the company, the promotion is valid until Jan. ... expand the UK market. , The prom dresses in ... and styles: A-line strapless, empire strapless chiffon, one shoulder, ...
(Date:12/25/2014)... 25, 2014 When head lice hits a ... a frenzy to get rid of it while keeping it ... Coral Gables now have the solution right in their neighborhood: ... location, Lice Troopers provides full spectrum head lice screening and ... area, including Sunset, Key Biscayne, Brickell, Coconut Grove, Kendall, Pinecrest ...
(Date:12/25/2014)... News) -- Among early stage breast cancer patients who ... one percent will eventually develop leukemia as a result ... finding comes from a review of more than 20,000 ... it suggests that the risk for developing treatment-related leukemia, ... thought. "The frequency of bone marrow cancers such ...
(Date:12/25/2014)... Plugin creators from Pixel Film Studios ... customizable business presentation tool made specifically for Final ... business tool, users can now display their stats and ... Film Studios. “ProFire 5k gives users a multiple options ... to a presentation” , Pixel Film Studios takes the ...
Breaking Medicine News(10 mins):Health News:Nintedanib Colorectal Cancer Market Analysis and Forecast to 2023 Report at RnRMarketReserach.com 2Health News:Nintedanib Colorectal Cancer Market Analysis and Forecast to 2023 Report at RnRMarketReserach.com 3Health News:Nintedanib Colorectal Cancer Market Analysis and Forecast to 2023 Report at RnRMarketReserach.com 4Health News:Dylan Queen: Cheap Prom Dresses for the UK Market 2Health News:Coral Gables Florida Gets Ready to Be Lice-Free with Lice Troopers 2Health News:Breast Cancer Chemo Tied to Small But Significant Leukemia Risk 2Health News:Breast Cancer Chemo Tied to Small But Significant Leukemia Risk 3Health News:Announcing a new ProFire 5k plugin from Pixel Film Studios for Final Cut Pro X Professionals 2
... University of Helsinki, and Oncos Therapeutics, the biotech company ... oncolytic viruses, published initial results from their Advanced Therapy ... program is based on scientific research at the University ... clinical development. The results demonstrate an anti-tumor ...
... new nationwide registry will allow researchers to conduct larger, ... thousands of children in the United States. ... the American Recovery and Reinvestment Act of 2009, Cincinnati ... Eosinophilic Gastrointestinal Disorders (REGID). The first of ...
... Thanks to ... Surgery Institute of Southeast Texas. Houston plastic surgeon Dr. Leo Lapuerta leads the way in Houston ... ... area and lead to impressive results, especially as summer and beach season approaches. Recovery from a ...
... Counting calories ... Stacey Rosenfeld , ... York, NY (Vocus) -- With the incidence of disordered eating continuing to rise among children, ... eating disorder or have a poor body image, says New York City-based psychologist and eating ...
... many veterans, are at 8 times the risk after head ... People who are hospitalized for a traumatic brain injury face ... , That,s the finding of a team led by Charles ... Washington School of Medicine in Seattle and first author of ...
... ... featuring classic cars, live music, giveaways and more on Saturday, May 22, 2010 from 11:00 a.m. ... (Vocus) May 18, ... Classic Woody Car Show featuring classic cars, live music, giveaways and more on Saturday, May 22, ...
Cached Medicine News:Health News:Oncolytic viruses mediating anti-tumor immunity in human cancer patients 2Health News:National registry to track eosinophilic disorders 2Health News:New On-Q Pain Pump Making Tummy Tucks Easier 2Health News:Dr. Stacey Rosenfeld Offers Tips on How to Raise a Child who has Body Confidence and a Healthy Relationship with Food 2Health News:Dr. Stacey Rosenfeld Offers Tips on How to Raise a Child who has Body Confidence and a Healthy Relationship with Food 3Health News:Major Depression Often Follows Brain Injury 2Health News:Major Depression Often Follows Brain Injury 3Health News:Retirement Community in Arizona Hosts Classic Car Show with Live Music 2
(Date:12/24/2014)... NEW YORK and LONDON ... in global orthopedic industry are expected to grow at ... consumption in terms of value and volume. Hip, knee ... the developed world while in emerging economies they have ... failure rates are challenging the use of composites. Non-metallic ...
(Date:12/24/2014)... LifeScienceIndustryResearch.com adds 2014 ... Industry of 178 pages providing 10 company ... The 2014 Market Research Report ... professional and deep research report on Global ... report introduces Disposable Syringe basic information including ...
(Date:12/24/2014)... 2014 Tianyin Pharmaceutical Co., Inc. (NYSE ... patented biopharmaceutical, modernized traditional Chinese medicine (mTCM), branded ... that the Company achieved the Public Notice (Gong ... certificate of TPI,s Qionglai Facility (QLF) from the ... notice period is a significant procedure of GMP ...
Breaking Medicine Technology:Use of Composites in Orthopedic Industry to Reach $596 Million by 2020 2Use of Composites in Orthopedic Industry to Reach $596 Million by 2020 3World Disposable Syringe Market 2014 Report: China and Regional Analysis 2World Disposable Syringe Market 2014 Report: China and Regional Analysis 3World Disposable Syringe Market 2014 Report: China and Regional Analysis 4World Disposable Syringe Market 2014 Report: China and Regional Analysis 5TPI QLF Achieved Public Notice Status of GMP Certification 2TPI QLF Achieved Public Notice Status of GMP Certification 3
... CITY, Nov. 27 Booth - 3646/South Hall A - Varian ... of X-ray tubes and flat panel digital image detectors, will exhibit ... Chicago, Ill. from November 29 - December 3, 2009. Varian ... well as specialized cancer treatment technologies. , Varian,s exhibit will ...
... , WESTON, Fla., Nov. ... is pleased to announce that they have opened a regional marketing ... able to secure a location abroad, providing an essential gateway for ... products for children and adults to be distributed and sold globally. ...
Cached Medicine Technology:Varian Medical Systems to Highlight the Latest Digital Detectors, X-ray Tubes and Cancer Treatment Technology at the Radiological Society of North America (RSNA) Annual Meeting in Chicago 2American Scientific Resources Inc. Opens Shanghai Location 2
... Intersurgical Incorporated manufactures high ... and moisture exchangers, ventilator ... hand-held nebulizers and an ... and connectors for anesthesia ...
... has the right product for any patient ... intubated patients to patients with tracheotomies. These ... and critical care applications., ,The Unti-Mist ... patients and staff members. This entire product ...
... The Ulti-Mist™ HME product line has the ... pediatrics to adults and from intubated patients ... superior humidification for both anesthesia and critical ... HME/Filters provide maximum protection for patients and ...
Bacterial/Viral Filters for Anesthesia and Respiratory Applications...
Medicine Products: