Navigation Links
Allegheny Health Network Team Develops Biomarker for Early Detection of Esophageal Cancer
Date:8/6/2014

o esophageal cancer, such as Gastroesophageal Reflux Disease (GERD), Barrett’s Esophagus and high-grade dysplasia. Yet only a small minority of these patients develop life-threatening esophageal cancer. Better detection techniques are needed to identify the patients who will likely progress from these precursor lesions to cancer.”

The incidence of esophageal cancer is rapidly rising: up to 600 percent higher than in the 1970s. Survival is better when the disease is detected early, but unfortunately most patients do not sense difficulty swallowing until a tumor is advanced, making the development of biomarkers for the cancer critically important.

“We are excited and very optimistic about how this biomarker panel could be used to help patients, from early detection in at-risk patients, to risk-monitoring for patients with conditions that may lead to esophageal cancer, to monitoring the disease course in patients with cancer, adjusting their surveillance and treatment and potentially extending their lives,” said Ali Zaidi, MD, Director of Research at the AHN Esophageal and Thoracic Institute.

The development of blood-based biomarkers has improved early detection and impacted treatment of cancers such as ovarian and prostate, but development of blood-based esophageal cancer biomarkers has been hampered by the difficulty in identifying a single conserved and universal tracking marker.

Using tissue data from the esophageal cancer progression sequence, biomarkers having known cancer relevance and which are upregulated, were selected for testing in the serum. Followed by novel mathematical modeling, Dr. Jobe’s team was able to combine relevant and strong individual biomarkers into a panel that is accurate and reliable in detecting esophageal cancer.

The team used tissue samples obtained from the Department of Pathology at the University of Pittsburgh, representing patients with Barrett’s Esophagus, high-grade dysplasia and esophagea
'/>"/>

Source: PRWeb
Copyright©2014 Vocus, Inc.
All rights reserved

Page: 1 2 3

Related medicine news :

1. Study by Allegheny General Hospital Physicians Shows Oral Immunotherapy is a Safe, Effective Alternative to Allergy Shots for Ragweed Sufferers
2. West Penn Allegheny Health System is First in Pennsylvania to Perform Groundbreaking Minimally-Invasive Procedure for Swallowing Disorder
3. West Penn Allegheny Health System Physicians Pinpoint Gastroesophageal Reflux Disease (GERD) as a Factor That May Cause Chronic Cough
4. Allegheny Health Network Allergist Opposes OTC Sales of Corticosteroids in FDA Testimony, Citing Safety Concerns
5. Allegheny Health Network Becomes Official Medical Provider for Robert Morris University Athletic Program
6. Allegheny Health Network’s LifeFlight Marks 35th Year
7. Allegheny Health Network Partners with Region’s EMS Providers to Advance Treatment of Heart Attack Patients
8. Allegheny General Hospital Streamlines Testing for Liver Transplant Patients with Advanced Cardiac MRI
9. Allegheny Health Network Psychologist among Panelists at Senate Staff Briefing In Support of Legislation to Help Patients with Mental Health, Addiction Disorders
10. Four Allegheny Health Network Hospitals Named High Performers by U.S. News
11. Leading West Suburban OBGYN Practice, Premier Women’s Health, Joins Allegheny Health Network
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:9/18/2014)... This news release is available in German . ... at Technische Universitt Mnchen have won the ,International ... Hepatitis C Virus., As their prize, the scientists will ... the space station. The project involves crystallizing two proteins ... shuttle bringing these proteins to the International Space Station ...
(Date:9/18/2014)... (PRWEB) September 18, 2014 According to a ... and Services Market - Global Industry Analysis, Size, Share, Growth, ... and services market was valued at USD 77607.7 million in ... 5.9% from 2014 to 2020, to reach an estimated value ... products and services market is growing at a rapid pace ...
(Date:9/18/2014)... September 18, 2014 “Awesome” is the ... (Smart Teens Accepting Responsibility Today) Internship Program at ARDX ... Darcy C. describe the program as “Inspirational” and “Life-changing,” ... idea about what they would be doing during their ... do food runs and other mindless tasks,” but, instead ...
(Date:9/18/2014)... Maureen Salamon HealthDay Reporter ... in midlife may be associated with increased odds of ... years, new research suggests. The study, which did ... conditions, also suggested that the migraine-Parkinson,s association was stronger ... is a warning sign of a pending attack that ...
(Date:9/18/2014)... How much is a serving? , ... contributing to the obesity epidemic in the United States. ... how to manage portion size during the next “Healthy ... Humility House, 755 Ohltown Road, Austintown. , Registered dietician ... discussion and answer questions from 12:30 to 2 p.m. ...
Breaking Medicine News(10 mins):Health News:Hepatitis C virus proteins in space 2Health News:Dialysis Products and Services Market Expected to Reach USD 115.4 Billion Globally in 2020 2Health News:Dialysis Products and Services Market Expected to Reach USD 115.4 Billion Globally in 2020 3Health News:Dialysis Products and Services Market Expected to Reach USD 115.4 Billion Globally in 2020 4Health News:ARDX Internship Helps Students to START on the Right Business Path 2Health News:ARDX Internship Helps Students to START on the Right Business Path 3Health News:ARDX Internship Helps Students to START on the Right Business Path 4Health News:Are Migraines in Middle Age Tied to Raised Parkinson's Risk Later? 2Health News:Are Migraines in Middle Age Tied to Raised Parkinson's Risk Later? 3Health News:HMHP Workshop Addresses Portion Control 2
... newsletter deals with two pressing societal concerns the ... perspective of older minority adults. WHAT,S HOT is ... (GSA), the country,s largest interdisciplinary organization devoted to the ... by sanofi-aventis. Based on presentation highlights from GSA,s ...
... puzzle, because less visceral fat should mean less obesity-linked ... -- Blacks tend to carry around less of a ... though they suffer more from obesity-linked illness, researchers report. ... guidelines may need to be tailored to specific racial ...
... , , SAN DIEGO, Dec. 18 I AM ... an event to bring peace and wellness to children and their ... suffer from illnesses such as asthma, diabetes and cancer, as well ... stress and pain. This will be an inspiring and eye-opening event ...
... University of Vigo, Rutgers University in the United States ... developed "laser spinning", a novel method of producing glass ... bioglass nanofibres, the bioactive glass used in regenerating bone, ... possible to produce glass nanofibres of compositions that would ...
... , ... an inescapable part of modern life. According to Patt Lind-Kyle, the key to thriving (instead ... instead of allowing it to manage you. , ... Fulton, CA (PRWEB) December 18, 2009 -- Stress and worry consume many ...
... Local ... ... 2009 -- Milton & DeKruif, a Glendale - based law firm serving the needs of ... development campaign in order to raise its market visibility in front of new and existing ...
Cached Medicine News:Health News:Blacks Have Less 'Bad Fat' Than Whites 2Health News:Blacks Have Less 'Bad Fat' Than Whites 3Health News:Blacks Have Less 'Bad Fat' Than Whites 4Health News:Kids Discover Their Magic for Helping Patients and Families 2Health News:Dancing in the Eye of the Hurricane: How to Stop Running from Stress…and Start Asking It to Dance 2Health News:Dancing in the Eye of the Hurricane: How to Stop Running from Stress…and Start Asking It to Dance 3Health News:Dancing in the Eye of the Hurricane: How to Stop Running from Stress…and Start Asking It to Dance 4Health News:Milton & DeKruif Launches New Client Development Campaign 2
(Date:9/18/2014)... -- New device to be showcased at ... medical technology company focused on Navigated Brain Stimulation (NBS), announces ... noninvasive presurgical mapping in clinical neurosurgery. The new device will ... of October 2014, one in Europe ... The new NBS 5 system combines MRI-guided Transcranial ...
(Date:9/17/2014)... Sept. 17, 2014 North America Gynecological ... GlobalData,s new report, "North America ... market data on the North America Gynecological Devices ... US dollars, volume (in units) and average prices ... Sterilization Devices (Transcervical Sterilization Devices (Micro-inserts) and Mechanical ...
(Date:9/17/2014)... , Sept. 17, 2014 BRIC ... Summary GlobalData,s new report, "BRIC ... market data on the BRIC Gynecological Devices market. ... dollars, volume (in units) and average prices (in ... Devices (Transcervical Sterilization Devices (Micro-inserts) and Mechanical Sterilization ...
Breaking Medicine Technology:Nexstim Launches Next Generation NBS 5 System 2Nexstim Launches Next Generation NBS 5 System 3Nexstim Launches Next Generation NBS 5 System 4Nexstim Launches Next Generation NBS 5 System 5North America Gynecological Devices Market Outlook to 2020 2North America Gynecological Devices Market Outlook to 2020 3BRIC Gynecological Devices Market Outlook to 2020 2BRIC Gynecological Devices Market Outlook to 2020 3
... May 21 BARC, a global,central laboratory today ... trials currently being performed in South Africa by ... vaccine trials are designed to answer scientific questions,that ... safe and effective,vaccine to prevent HIV infection. The ...
... and long-term survivors validate Jennerex ... breakthrough product approach, SAN ... Francisco, CA and Ottawa, Ontario), and its South,Korean partner Green ... its first-in-class lead product JX-594 were published in,the premier journal ...
Cached Medicine Technology:BARC Announces Long-Term Cooperation In South African Biobanking for HIV Vaccine Trials 2BARC Announces Long-Term Cooperation In South African Biobanking for HIV Vaccine Trials 3Jennerex Publishes Promising Results from Cancer Clinical Trial of JX-594 in Lancet Oncology 2Jennerex Publishes Promising Results from Cancer Clinical Trial of JX-594 in Lancet Oncology 3Jennerex Publishes Promising Results from Cancer Clinical Trial of JX-594 in Lancet Oncology 4
Aerosolized Medication Device for Infants. An alternative to aerosol blow-by., ,The PediNeb™ was designed to enhance the delivery of aerosolized medication, while reducing the apprehension enc...
... Respiratory Products, ,Westmed designs, manufacturers and ... and Respiratory professionals. Our mission is to ... clinician's ability to deliver quality medical care ... line. , ,Our web site is ...
... ULTRA compressor. This high output compressor can ... medication to the patient's lungs. When combined ... LC STAR® Reusable Nebulizer, the particle size ... retention into the lungs. With less medication ...
... Air., ,Allied Healthcares Timeter® PCS 414 portable ... air compressors that you may wonder if its ... 414 features a durable, mar-resistant steel case thats ... weighs only 26.5 pounds. The PCS 414 has ...
Medicine Products: