Navigation Links
Allegheny Health Network Team Develops Biomarker for Early Detection of Esophageal Cancer
Date:8/6/2014

o esophageal cancer, such as Gastroesophageal Reflux Disease (GERD), Barrett’s Esophagus and high-grade dysplasia. Yet only a small minority of these patients develop life-threatening esophageal cancer. Better detection techniques are needed to identify the patients who will likely progress from these precursor lesions to cancer.”

The incidence of esophageal cancer is rapidly rising: up to 600 percent higher than in the 1970s. Survival is better when the disease is detected early, but unfortunately most patients do not sense difficulty swallowing until a tumor is advanced, making the development of biomarkers for the cancer critically important.

“We are excited and very optimistic about how this biomarker panel could be used to help patients, from early detection in at-risk patients, to risk-monitoring for patients with conditions that may lead to esophageal cancer, to monitoring the disease course in patients with cancer, adjusting their surveillance and treatment and potentially extending their lives,” said Ali Zaidi, MD, Director of Research at the AHN Esophageal and Thoracic Institute.

The development of blood-based biomarkers has improved early detection and impacted treatment of cancers such as ovarian and prostate, but development of blood-based esophageal cancer biomarkers has been hampered by the difficulty in identifying a single conserved and universal tracking marker.

Using tissue data from the esophageal cancer progression sequence, biomarkers having known cancer relevance and which are upregulated, were selected for testing in the serum. Followed by novel mathematical modeling, Dr. Jobe’s team was able to combine relevant and strong individual biomarkers into a panel that is accurate and reliable in detecting esophageal cancer.

The team used tissue samples obtained from the Department of Pathology at the University of Pittsburgh, representing patients with Barrett’s Esophagus, high-grade dysplasia and esophagea
'/>"/>

Source: PRWeb
Copyright©2014 Vocus, Inc.
All rights reserved

Page: 1 2 3

Related medicine news :

1. Study by Allegheny General Hospital Physicians Shows Oral Immunotherapy is a Safe, Effective Alternative to Allergy Shots for Ragweed Sufferers
2. West Penn Allegheny Health System is First in Pennsylvania to Perform Groundbreaking Minimally-Invasive Procedure for Swallowing Disorder
3. West Penn Allegheny Health System Physicians Pinpoint Gastroesophageal Reflux Disease (GERD) as a Factor That May Cause Chronic Cough
4. Allegheny Health Network Allergist Opposes OTC Sales of Corticosteroids in FDA Testimony, Citing Safety Concerns
5. Allegheny Health Network Becomes Official Medical Provider for Robert Morris University Athletic Program
6. Allegheny Health Network’s LifeFlight Marks 35th Year
7. Allegheny Health Network Partners with Region’s EMS Providers to Advance Treatment of Heart Attack Patients
8. Allegheny General Hospital Streamlines Testing for Liver Transplant Patients with Advanced Cardiac MRI
9. Allegheny Health Network Psychologist among Panelists at Senate Staff Briefing In Support of Legislation to Help Patients with Mental Health, Addiction Disorders
10. Four Allegheny Health Network Hospitals Named High Performers by U.S. News
11. Leading West Suburban OBGYN Practice, Premier Women’s Health, Joins Allegheny Health Network
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:3/5/2015)... In honor of National Drug Facts ... drug and alcohol abuse in schools and communities across ... with information on some of the dangers and statistics ... National Institute on Drug Abuse, this annual promotion of ... the illusions that teens and young adults get from ...
(Date:3/5/2015)... 05, 2015 Califia Farms , ... the natural products coffee drinks category[1], today unveils its ... West in Anaheim, Calif. Concentrated Cold Brew (CCB) ... Café, which democratizes the next wave of the coffee-taste ... need to become their own baristas. , Califia ...
(Date:3/5/2015)... York, NY (PRWEB) March 05, 2015 ... orthopedic Surgeon ( http://www.orthopedicsurgeonnyc.com ) has been named by ... the New York Metro area. Dr. Glashow has been ... its authoritative guide to the top specialty care doctors ... , The prestigious Castle Connolly program, which carefully screens ...
(Date:3/5/2015)... Nutrition Leaders, a premier purveyor of health, diet, ... Millennium 500 Creatine to its customers. Available from the ... creatine supplement that has been micronized to more quickly ... overall strength gains in users. , Creatine is a ... source in the body and helps fuel muscle contractions ...
(Date:3/5/2015)... 05, 2015 Wimbledon Health Partners ... vascular, echocardiogram and NCV testing, announced the ... Chief Medical Officer. Dr. Artel will be responsible for ... the WimbledonMED program and the continued growth and support ... working with Wimbledon Health Partners as a consulting physician ...
Breaking Medicine News(10 mins):Health News:A Forever Recovery Issues New Tips for Sobriety for National Drug Facts Week 2Health News:Califia Farms Personalizes At-Home Coffee Experience with the Launch of Concentrated Cold Brew Coffee 2Health News:Califia Farms Personalizes At-Home Coffee Experience with the Launch of Concentrated Cold Brew Coffee 3Health News:Califia Farms Personalizes At-Home Coffee Experience with the Launch of Concentrated Cold Brew Coffee 4Health News:Dr. Jonathan Glashow, NYC Orthopedic Surgeon, Named Top Doctor: New York Metro Area 2Health News:Nutrition Leaders Offers Reformulated Millennium 500 German Grade Creatine 2Health News:Wimbledon Health Partners Appoints Chief Medical Officer to Attain Medicare Market Share 2Health News:Wimbledon Health Partners Appoints Chief Medical Officer to Attain Medicare Market Share 3
... in a Queen,s University-led study do not have an influenza ... tested. In addition, key players were not involved in developing ... not good enough just to have a plan, you have ... will work in an emergency," says Dick Zoutman, Queen,s professor ...
... , AKRON, Ohio , Feb. 10 ... is launching its first bachelor,s degree programs in its 40-year ... Administration with a Business Management concentration Bachelor of Science ... Information Management Bachelor of Science – Technology Management with ...
... or GAD, have abnormalities in the way their brain unconsciously ... School of Medicine study, and the study authors say the ... our understanding of how emotion is regulated in everyday life. ... American Journal of Psychiatry. According to the National ...
... ... celiac disease, one of the most common and under-diagnosed autoimmune diseases, it,s symptoms, and how ... a year, one being day-time Emmy Award winner, Elisabeth Hasselbeck of ABC’s “The View”. ... (PRWEB) February 11, 2010 -- ...
... removal of tumors, study found , WEDNESDAY, Feb. 10 (HealthDay ... levels of spiritual thinking and feeling in patients, a finding ... and the physical makeup of the mind, researchers say. , ... Neuron , are based on research in patients who had ...
... , , PUYALLUP, Wash. , ... IT stimulus and the American Recovery and Reinvestment Act ... comprehensive digital imaging and data management integration project with ... paying dividends for MINW patients even after the completion ...
Cached Medicine News:Health News:Akron Institute of Herzing University Launches Its First Bachelor's Degree Programs to Prepare Students for Even Greater Success in Business, Health Care and IT 2Health News:Akron Institute of Herzing University Launches Its First Bachelor's Degree Programs to Prepare Students for Even Greater Success in Business, Health Care and IT 3Health News:People with anxiety disorder less able to regulate response to negative emotions, study shows 2Health News:People with anxiety disorder less able to regulate response to negative emotions, study shows 3Health News:Multi-Award Winning Author Tina Turbin Interviews Special Guest Dr. Peter H.R. Green, M.D. On The Thrive in Balance Radio Show 2Health News:Physical Changes in Brain Linked to Altered Spirituality 2Health News:Medical Imaging Northwest Completes Phase I of Its Healthcare IT Integration to Maintain Patient Care Improvements 2Health News:Medical Imaging Northwest Completes Phase I of Its Healthcare IT Integration to Maintain Patient Care Improvements 3
(Date:3/5/2015)... , Mar. 05, 2015 Research and ... the addition of the "Global Pharma US ... Cost Optimization Plays Major Role In Shaping Up ... to their offering. Strategy Diversification ... in healthy Cash position- Will accelerate Next wave ...
(Date:3/5/2015)... N.J. , March 5, 2015  ContraVir Pharmaceuticals, ... focused on the development and commercialization of targeted antiviral ... 27 th Annual ROTH Conference, to be held ... James Sapirstein , Chief ... business during his live presentation and will be available ...
(Date:3/5/2015)... March 5, 2015  Asterias Biotherapeutics, Inc. (NYSE MKT: ... of regenerative medicine, announced today that Atlanta ... rehabilitation hospitals for spinal cord injury and brain injury, ... of AST-OPC1 (oligodendrocyte progenitor cells) in newly injured patients ... (SCI). The Phase 1/2a trial follows ...
Breaking Medicine Technology:Global Pharma US & EU Outlook 2015: First -In-Class Innovations and Cost Optimization Plays Major Role In Shaping Up Business for Large Cap Pharmaceutical Companies 2Global Pharma US & EU Outlook 2015: First -In-Class Innovations and Cost Optimization Plays Major Role In Shaping Up Business for Large Cap Pharmaceutical Companies 3ContraVir to Present at 27th Annual ROTH Conference 2Asterias Biotherapeutics Initiates Patient Enrollment for Phase 1/2a Clinical Trial of AST-OPC1 in Newly Injured People with Complete Cervical Spinal Cord Injury 2Asterias Biotherapeutics Initiates Patient Enrollment for Phase 1/2a Clinical Trial of AST-OPC1 in Newly Injured People with Complete Cervical Spinal Cord Injury 3Asterias Biotherapeutics Initiates Patient Enrollment for Phase 1/2a Clinical Trial of AST-OPC1 in Newly Injured People with Complete Cervical Spinal Cord Injury 4
... , AUSTIN, Texas, Sept. 14 WillWalk, ... forefront of ending Paralysis. WillWalk will raise $3 million to help fund ... Injury (SCI). , , The money raised will fund ... cells being used are a non-controversial adult stem cell from umbilical cord ...
... , SAN DIEGO, Sept. 13 NexBio, Inc. ... against H1N1 influenza and NAI-resistant influenza at the 2009 Interscience ... September 13, 2009, in San Francisco, CA. The work ... Disease Control and Prevention (CDC), University of Hong Kong, and ...
Cached Medicine Technology:Paralyzed Artist Launches WillWalk Foundation to Cure Paralysis with Breakthrough Stem Cell Research 2NexBio(R) Presents DAS181 (Fludase(R)*) Potently Inhibits Novel Swine-Origin A(H1N1) and NAI-Resistant Influenza Viruses, at ICAAC 2009 2NexBio(R) Presents DAS181 (Fludase(R)*) Potently Inhibits Novel Swine-Origin A(H1N1) and NAI-Resistant Influenza Viruses, at ICAAC 2009 3
The Mini Vidas is a compact version of the Vidas system with a built-in computer, keyboard and printer. Two independent sections each accept six tests and can process up to 12 samples simultaneously....
... ARUP Laboratories is a national reference ... laboratory research and development. ARUP offers an ... unique medical tests in clinical and anatomic ... ARUP Laboratories' clients include more than half ...
... is a national reference laboratory and a ... development. ARUP offers an extensive test menu ... in clinical and anatomic pathology. Owned by ... include more than half of the nation's ...
... reference laboratory and a worldwide leader in ... an extensive test menu of highly complex ... anatomic pathology. Owned by the University of ... half of the nation's university teaching hospitals ...
Medicine Products: