Navigation Links
All-they-can-eat diet for lab mice and rats may foster inaccurate test results
Date:7/18/2012

The widespread practice of allowing laboratory rats and mice to eat as much as they want may be affecting the outcome of experiments in which scientists use these "test-tubes-on-four-feet" to test new drugs and other substances for toxicity and other effects. That's the conclusion of a new analysis published in ACS' journal Chemical Research in Toxicology.

Laboratory mice and rats serve as stand-ins for people for research that cannot be done on humans. In the article, Gale Carey and Lisa Merrill point out that the millions of lab rodents used in laboratory studies each year have a nutritional status that is different from other test animals. While other test animals are fed meals, rodents have round-the-clock access to food. And eat they do, gaining more weight and more body fat than meal-fed rodents. The authors cite other research indicating that lab rodents with free access to food tend to develop abnormally high blood fat levels, high cholesterol, nerve and heart damage, cancer and other disorders.

Their analysis of 54 studies concluded that having free access to food is likely to affect the results of tests for the toxicity and cancer-causing effects of new drugs and other substances in rodents, and could be the reason why such studies have been varying so much in recent years. "Therefore, it is crucial that feeding regimen be carefully considered in designing toxicology experiments," say the authors.


'/>"/>

Contact: Michael Bernstein
m_bernstein@acs.org
202-872-6042
American Chemical Society
Source:Eurekalert

Page: 1

Related medicine news :

1. Child abuse and foster care admissions increase when parents use methamphetamines
2. 2 new vitamin D blood tests are often highly inaccurate, researchers say
3. A better way to test new treatments? Approach could help patients and give useful results
4. Green Tea Weight Loss Results and Health Benefits Revealed
5. EVINCI results could lead to 75 percent reduction of invasive procedures for patients with suspected CAD
6. Long-term testosterone treatment for men results in reduced weight and waist size
7. ACP-New York State Chapter partnership results in patient safety organization recognition
8. Tight Blood-Sugar Control Shows Mixed Results for Health of Kidneys: Study
9. Quality of care, other issues may cause worse results in black prostate cancer surgery patients
10. Automated insulin dosage titration system demonstrates positive clinical study results
11. Stem Cell Study Shows Promising Results Against Heart Failure
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:11/28/2014)... 28, 2014 On Monday, November 24, ... will present Feeding America Eastern Wisconsin with a check ... to donate a portion of proceeds to Feeding America ... “7 Days, 7 Ways to Save” with Turbana bananas ... were two for $4 and Turbana bananas were 29 ...
(Date:11/28/2014)... Dr. Paul Vitenas, one of the most ... Glow Holiday Event for those in the area that would like ... Glitter & Glow will take place on December 11, 2014, from ... the heart of Houston at 4208 Richmond Ave. , “We ... you will come and celebrate the season with us on December ...
(Date:11/28/2014)... Planning on seconds at Thanksgiving Day dinner this year? If ... reflux disease (GERD) -- a few steps may help minimize ... throat specialist at Lenox Hill Hospital in New York City, ... Pace yourself. Rather than have one ... day. It,s also a good idea to have a healthy ...
(Date:11/28/2014)... Los Angeles, CA (PRWEB) November 28, 2014 ... Tonight online, reported during the hugely popular, ... 24th, the antismoking organization Truth launched ground-breaking celebrity ... aged 18-49. The MTV viewership figures were estimated ... pointing Truth antismoking ads placed the spotlight on ...
(Date:11/28/2014)... (PRWEB) November 28, 2014 Lice Troopers Lice ... of its in-home head lice service for moms in ... the center of Coral Gables on Pone De-leon Blvd in ... Harbor Islands that service Miami-Dade & Broward. Lice Troopers ... in South Florida which has been treating families for several ...
Breaking Medicine News(10 mins):Health News:Turbana Partners With Sendik's Food Market to Donate $11,500 to Local Hunger-Relief Non-Profit 2Health News:Turbana Partners With Sendik's Food Market to Donate $11,500 to Local Hunger-Relief Non-Profit 3Health News:Cosmetic Surgeon Dr. Paul Vitenas to Host Glitter & Glow Holiday Event 2Health News:Cosmetic Surgeon Dr. Paul Vitenas to Host Glitter & Glow Holiday Event 3Health News:Don't Let Chronic Heartburn Spoil Your Thanksgiving Feast 2Health News:Freedom Laser Therapy Applauds American Legacy’s Creative Advertising Targeting Celebrity Smokers 2Health News:Freedom Laser Therapy Applauds American Legacy’s Creative Advertising Targeting Celebrity Smokers 3Health News:Freedom Laser Therapy Applauds American Legacy’s Creative Advertising Targeting Celebrity Smokers 4Health News:Freedom Laser Therapy Applauds American Legacy’s Creative Advertising Targeting Celebrity Smokers 5Health News:Lice Troopers Lice Removal Service Expands in Miami-Dade 2
... , , SCHAUMBURG, Ill., Sept. ... American Veterinary Medical Association (AVMA) reveal an economic mixed bag when ... , The survey results appear in the ... 1, 2009, article entitled, "Employment, starting salaries, and educational indebtedness of ...
... , SHANGHAI, Sept. 1 /PRNewswire-Asia/ ... manufacturer and distributor,of healthcare-related disinfectants in China, put forward ... with the spread of H1N1. , ... to prevent and control,infectious diseases, and it will work ...
... HAIKOU CITY, China, Sept. 1 /PRNewswire-Asia-FirstCall/ -- China ... and markets specialty pharmaceutical products in China, today,announced it will ... -- Rodman & Renshaw Annual Global Investment Conference, held September, ... New York Palace Hotel in New York City. Management, ...
... BARCELONA, Spain, Sept. 1 New data ... (pitavastatin), high-density lipoprotein cholesterol (HDL-C) concentrations increased, and nearly ... with results sustained over 52 weeks. Additionally, LIVALO was ... as measured by reduction in LDL-C from baseline. The ...
... , , ... largest and most trusted source for online care, announced today that it ... which secured $7.5 million in financing in January of this year, opened ... leaders in Chicago,s investment community. , , ...
... Officials expect return of virus that first surfaced last spring ... H1N1 swine flu break out on U.S. college campuses, school ... preventative steps to keep the virus from spreading further. ... young people, who are often the least likely to take ...
Cached Medicine News:Health News:AVMA Survey Indicates Most Starting Salaries Are Up for New Veterinarians 2Health News:AVMA Survey Indicates Most Starting Salaries Are Up for New Veterinarians 3Health News:Which is the Real Terminator of H1N1 Disease, the Antisepsis or the Vaccine? 2Health News:Which is the Real Terminator of H1N1 Disease, the Antisepsis or the Vaccine? 3Health News:China Pharma Holdings, Inc. Announces Participation in September Conferences 2Health News:LIVALO(R) Demonstrates Sustained, Long-Term Efficacy and Tolerability in Patients With Primary Hypercholesterolemia or Mixed Dyslipidemia 2Health News:LIVALO(R) Demonstrates Sustained, Long-Term Efficacy and Tolerability in Patients With Primary Hypercholesterolemia or Mixed Dyslipidemia 3Health News:LIVALO(R) Demonstrates Sustained, Long-Term Efficacy and Tolerability in Patients With Primary Hypercholesterolemia or Mixed Dyslipidemia 4Health News:LIVALO(R) Demonstrates Sustained, Long-Term Efficacy and Tolerability in Patients With Primary Hypercholesterolemia or Mixed Dyslipidemia 5Health News:Growth Attracts Additional Investors to Sittercity.com 2Health News:Swine Flu on Campuses Boosts Call for Vaccinations 2
(Date:11/27/2014)... - New Solution That Makes ... JIN Co., Ltd. will launch JINS MEME "ACADEMIC PACK" ... yen or $5,000 (without tax /including two pairs of JINS ... a dedicated solution of "JINS MEME" to academic researchers, and ... generated by electrooculography and six-axis sensors without API. (*Physiological data ...
(Date:11/26/2014)... Mass. , Nov. 26, 2014   ... AEX: PHIA) today announced expanded availability of its ... DuraDiagnost, DigitalDiagnost, MobileDiagnost wDR, MobileDiagnost Opta[i] , ProGrade ... these solutions now available in the U.S., and ... markets, the portfolio offers Philips, customers innovative solutions ...
(Date:11/26/2014)... , Nov. 26, 2014  Perrigo Company plc ... global provider of "Quality Affordable Healthcare Products®," today announced ... relating to the sale of 6,809,210 ordinary shares at ... the full exercise of the option to purchase up ... Securities LLC and Barclays Capital Inc., as representatives of ...
Breaking Medicine Technology:JIN to Launch JINS MEME ACADEMIC PACK in Late April 2015 2JIN to Launch JINS MEME ACADEMIC PACK in Late April 2015 3Philips expands global reach of diagnostic X-Ray solutions 2Philips expands global reach of diagnostic X-Ray solutions 3Perrigo Company plc Announces The Closing Of Its Registered Public Offering Of Ordinary Shares 2Perrigo Company plc Announces The Closing Of Its Registered Public Offering Of Ordinary Shares 3Perrigo Company plc Announces The Closing Of Its Registered Public Offering Of Ordinary Shares 4
... DALLAS , June 21, 2010 ... store. , , , ... Cardiovascular Devices Market Outlook to 2016 (, http://www.reportsandreports.com/market-reports/netherlands-cardiovascular-de ,vices-market-outlook-to-2016/) , ... (Due to the length of these ...
... 21 Medco Health Solutions, Inc. (NYSE: MHS ) and ... joint venture with a long-term goal of improving patient health and helping to ... , , ... , , ...
Cached Medicine Technology:Cardiovascular Devices Market Outlook June Update by ReportsandReports 2Cardiovascular Devices Market Outlook June Update by ReportsandReports 3Cardiovascular Devices Market Outlook June Update by ReportsandReports 4Cardiovascular Devices Market Outlook June Update by ReportsandReports 5Cardiovascular Devices Market Outlook June Update by ReportsandReports 6Cardiovascular Devices Market Outlook June Update by ReportsandReports 7Cardiovascular Devices Market Outlook June Update by ReportsandReports 8Cardiovascular Devices Market Outlook June Update by ReportsandReports 9Cardiovascular Devices Market Outlook June Update by ReportsandReports 10Medco and Celesio Announce Pan-European Joint Venture to Enhance Quality of Clinical Care and Reduce Overall Healthcare Costs 2Medco and Celesio Announce Pan-European Joint Venture to Enhance Quality of Clinical Care and Reduce Overall Healthcare Costs 3Medco and Celesio Announce Pan-European Joint Venture to Enhance Quality of Clinical Care and Reduce Overall Healthcare Costs 4Medco and Celesio Announce Pan-European Joint Venture to Enhance Quality of Clinical Care and Reduce Overall Healthcare Costs 5Medco and Celesio Announce Pan-European Joint Venture to Enhance Quality of Clinical Care and Reduce Overall Healthcare Costs 6Medco and Celesio Announce Pan-European Joint Venture to Enhance Quality of Clinical Care and Reduce Overall Healthcare Costs 7
1000 L, Bulk Recommended for 500 and 1000 L pipettes....
Inquire...
... way to order tips. Each box contains 1000 ... which contains 200 tips (4 bags of 50 ... of 200 tips per pack. Bulk Packs are ... be opened for quick access to Gilsons Diamond ...
... Finntips have been designed to optimize the ... of our tip products is widely recognized ... range has been extended over the years ... standard and special tips including filter tips, ...
Medicine Products: