Navigation Links
Algae extract increases good cholesterol levels, Wayne State research finds
Date:7/6/2012

Detroit - A Wayne State University researcher has found that an extract from algae could become a key to regulating cardiovascular disease.

In a study funded by Health Enhancement Products of Bloomfield Hills, Mich., Smiti Gupta, Ph.D., assistant professor in the department of nutrition and food science in the College of Liberal Arts and Sciences, has found that dietary intake of ProAlgaZyme increased the level of high-density lipoprotein (HDL) in an animal model.

While medications for the control of high plasma cholesterol levels such as statins and numerous dietary supplements primarily function by lowering levels of low-density lipoproteins (LDL), or "bad cholesterol," Gupta's research explores the effects of raising levels of HDL, or "good cholesterol," which work in part by carrying cholesterol out of the arterial wall.

Results of her study, titled "ProAlgaZyme and its Sub-fractions Increase Plasma HDL-Cholesterol via Up Regulation of ApoA1, ABCA1 and SRB1 and Inhibition of CETP in Hypercholesterolemic Hamsters," were published recently in the Journal of Nutrition and Dietary Supplements.

"The cholesterol mechanism is crucial to heart disease," Gupta said. "Very few agents increase good cholesterol, but we found that this algae extract does. The ratio of total to HDL cholesterol improved significantly. This result, if replicated in humans, would be consistent with a decreased risk of heart disease."

ProAlgaZyme, a clear liquid, was administered as part of the drinking fluid over four weeks. In addition to increasing HDL levels, the group found that it also changed the expression of genes involved in the reverse cholesterol transport mechanism. And while they don't know exactly how it will function in humans, Gupta said other research suggests a similar outcome.

"Its biological effect over time and toxic effects, if any, need to be further investigated in a long-term study in an animal model before testing its effects in humans," she said. "But this is a step in the right direction, since increased HDL is considered an important therapeutic target for improvement of the lipid profile and thus reduction of the risk for cardiovascular disease."


'/>"/>

Contact: Julie O'Connor
julie.oconnor@wayne.edu
313-577-8845
Wayne State University - Office of the Vice President for Research
Source:Eurekalert

Related medicine news :

1. Childhood adversity increases risk for depression and chronic inflammation
2. Why smoking is BAD for the Fallopian tube -- and increases the risk of ectopic pregnancy
3. Why cancer rate increases with age (its not what you think)
4. Viewing terrorist attacks on TV increases pain intensity -- Ben-Gurion U. researchers
5. Bacterial Vaginosis Increases Female-to-Male HIV Transmission Risk
6. Lung nodule matching software dramatically increases radiologists efficiency
7. Prenatal exposure to common household chemical increases risk for childhood eczema, study says
8. US Drug Watchdog Dramatically Increases Their Efforts To Get All Recalled DePuy ASR Hip Implant Recipients Identified To The Best Possible Attorneys Before Time Runs Out
9. Tai Chi increases brain size, benefits cognition in randomized controlled trial of Chinese elderly
10. Study shows no evidence medical marijuana increases teen drug use
11. Haematopoietic stem cell transplantation increases survival in systemic sclerosis patients
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:6/26/2017)... (PRWEB) , ... June 26, 2017 , ... ... Male Fertility & Sexual Medicine Specialists, in collaboration with the Fertility Center of ... male fertility care: PESA (percutaneous epidydimal sperm aspiration) and TESA (percutaneous testicular sperm ...
(Date:6/26/2017)... (PRWEB) , ... June 26, 2017 , ... ... coding staff, and consumers are seeing lots of red these days. According to ... inaccurate charges that result from medical coding errors(1). Some studies point to Electronic ...
(Date:6/25/2017)... ... June 25, 2017 , ... Republicans in the United ... replace Obamacare, called the Better Care Reconciliation Act. It differs significantly from the American ... need to be reconciled in committee, or the House will have to take up ...
(Date:6/24/2017)... ... June 24, 2017 , ... Genes Advice, ... medications in select Florida and Texas doctors' offices and clinics. This breakthrough testing ... of genetic testing recognizes the role genes play in determining an individual's tolerance ...
(Date:6/23/2017)... RI (PRWEB) , ... June 23, 2017 , ... ... Care Network today announced the launch of Care Management Alerts and Dashboards, an ... 140,000 patients throughout Rhode Island. , RIQI’s Care Management Alerts and Dashboards provide ...
Breaking Medicine News(10 mins):
(Date:6/16/2017)... Datascope Corp. is voluntarily performing a worldwide field correction of certain Intra-Aortic Balloon ... ... CS100i ... 0998-UC-0446HXX; 0998-UC-0479HXX 0998-00-3013-XX;  0998-UC-3013-XX 0998-00-3023-XX;  ... This field correction also applies to any System 98 ...
(Date:6/14/2017)... , June 14, 2017  ivWatch LLC, a ... effectiveness of intravenous (IV) therapy, is pleased to announce ... category of Nonsurgical Hospital Supplies and Equipment at the ... program for the medtech industry. The award was presented ... Jacob K. Javits Center in New York ...
(Date:6/14/2017)... 2017  In 2016, Embodied Labs took ... competition and came away with $25,000 in seed-fund investment. ... Forbes as "entering the life of another" and by ... "empathy to medical professionals in an entirely new dimension." ... a finalist for the Department of Education,s EdSimChallenge, where ...
Breaking Medicine Technology: