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Alexza Reports 2008 Year-End Financial Results and Updates Clinical Pipeline Status
Date:3/10/2009

Endo Pharmaceuticals, Inc. to terminate the license agreement with all rights to AZ-003 reverting back to Alexza. Alexza and Endo entered into this license agreement in December 2007. The Company does not expect to pursue the development of AZ-003 without a partner.
  • AZ-002 (Staccato alprazolam). Alexza is developing AZ-002 for the acute treatment of panic attacks associated with panic disorder. AZ-002 has completed Phase 1 testing and one Phase 2a proof-of-concept study in panic attacks, an indication the Company is not planning to pursue. However, given the demonstrated safety profile, the successful and reproducible delivery of alprazolam, and the IV-like pharmacological effect demonstrated to date, Alexza and Symphony Allegro are assessing AZ-002 for other possible indications and renewed clinical development.
  • AZ-002 has been licensed to Symphony Allegro, and the Company has the right to repurchase all rights to this product candidate.

    Conference Call Information

    Alexza will host a conference call today, March 10, 2009, at 4:30 p.m. Eastern Time. A replay of the call will be available for two weeks following the event. The conference call, replay and webcast are open to all interested parties.

    To access the conference call via the Internet, go to www.alexza.com, under the "Investor Relations" link. Please join the call at least 15 minutes prior to the start of the call to ensure time for any software downloads that may be required. Interested parties may also pre-register to avoid pre-call delays at

    https://www.theconferencingservice.com/prereg/key.process?key=P9J9NFRUU.

    To access the live conference call via phone, dial 888-713-4213. International callers may acc
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    SOURCE Alexza Pharmaceuticals, Inc.
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