Navigation Links
Alcoholism's effect on sleep persists during long periods of sobriety
Date:9/30/2009

Westchester, Ill. - A study in the Oct.1 issue of the journal Sleep shows that long-term alcoholism affects sleep even after long periods of abstinence, and the pattern of this effect is similar in both men and women.

Results indicate that in long-term alcoholics who had not had a drink for up to 719 days, the percentage of slow wave sleep was significantly lower (6.6% in men, 11.1% in women) than in controls (12.0% in men, 12.1% in women). Alcoholics also had significantly more stage 1 non-rapid eye movement (NREM) sleep (8.5% in men, 6.3% in women) than controls (6.2% in men, 5.6% in women). According to the authors, having less deep, slow wave sleep and more light, stage 1 sleep is reflective of poorer sleep quality, which could act as an exacerbating factor in alcoholics' cognitive decline.

Although women had better sleep efficiency and fewer wake periods than men, no significant interactions between sex and alcoholism diagnosis were found for any measures. This suggests that women show the same general pattern of alcoholism-related sleep changes as men.

Principal investigator Ian Colrain, PhD, director of the SRI International Human Sleep Research Program and a professional fellow in psychology at the University of Melbourne in Australia, also was surprised to find that a significant increase in the percentage of REM sleep persisted in alcoholics who had abstained from drinking for an extended period.

"Previously the REM changes in the acute detox period were assumed to be related to a rebound of the REM suppression effects of alcohol," said Colrain. "The persistence indicates that there is some possibly permanent structural/functional change in REM regulation mechanisms produced by long-term alcohol abuse."

The study involved 42 alcoholics (mean age 49 years, 27 men) who were recruited from an inpatient treatment program and 42 controls (mean age 51 years, 19 men). Estimated lifetime alcohol consumption was significantly higher in male alcoholics (1,607.2 kg) than female alcoholics (843.7 kg). All participants were screened for medical, psychiatric and sleep problems, and their sleep was measured by a full night of polysomnography following an adaptation night. Data were collected from multiple scalp sights and subjected to power spectral analysis. Sleep architecture and electroencephalogram (EEG) spectral power measures were evaluated for the effects of alcoholism diagnosis and sex using age as a covariate.

Results also show that perceived sleep as measured by the Pittsburgh Sleep Quality Index (PSQI) was significantly worse in alcoholics than in controls. Estimated lifetime alcohol consumption was significantly related to the scores on the PSQI in men and women, with higher lifetime consumption predicting less sleep satisfaction. Spectral analysis revealed that alcoholics had significantly reduced levels of slow wave activity during NREM sleep but not during REM sleep, showing that the reduction in slow wave activity in alcoholism is sleep-state specific.

Colrain said that there is a substantial body of literature describing the functional correlates of the structural damage produced by long-term alcohol abuse. Many aspects of psychological functioning are affected by damage to the frontal cortex, including those that relate to judgment and risk taking. He added that there is a growing appreciation for the role of slow wave sleep in supporting memory and other mental functions.


'/>"/>

Contact: Kelly Wagner
kwagner@aasmnet.org
708-492-0930
American Academy of Sleep Medicine
Source:Eurekalert

Related medicine news :

1. New treatment effective in counteracting cocaine-induced symptoms
2. Use of certain lipid measures not more effective in predicting coronary heart disease
3. HPV vaccine does not appear to be effective for treating pre-existing HPV infection
4. Effectiveness of mouse breeds that mimic Alzheimers disease symptoms questioned
5. Stanford study highlights cost-effective method of lowering heart disease risks
6. New study may explain Vioxx side-effects
7. Jefferson specialists studying innovative surgery for effectively treating sleep apnea
8. Case Management Cost-Effective Way to Cut Heart Risks
9. ResMed Names Kieran Gallahue as Chief Executive Officer, Effective January 1, 2008.
10. Nasal Anthrax Vaccine Proves Effective in Animal Study
11. Family-based treatment more effective than supportive psychotherapy in treating bulimia
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:10/13/2017)... ... October 13, 2017 , ... Coveros, ... Development, has been awarded a contract by the Center for Medicare and Medicaid ... to accelerate the enterprise use of Agile methodologies in a consistent and high ...
(Date:10/12/2017)... ... October 12, 2017 , ... ... sleep apnea using cutting-edge Oventus O2Vent technology. As many as 18 ... characterized by frequent cessation in breathing. Oral appliances can offer significant relief to ...
(Date:10/12/2017)... (PRWEB) , ... October 12, 2017 , ... The American ... Excellence to Carol Friedman, PhD, FACMI, during the Opening Session of AMIA’s Annual Symposium ... 8. , In honor of Morris F. Collen, a pioneer in the field of ...
(Date:10/12/2017)... ... October 12, 2017 , ... HMP , a leader in healthcare events ... Magazine Eddie Digital Award for ‘Best B-to-B Healthcare Website.’ Winners were announced during the ... The annual award competition recognizes editorial and design excellence across a range of sectors. ...
(Date:10/12/2017)... , ... October 12, 2017 , ... ... the nation's first interactive health literacy software tool, and the Cancer Patient Education ... of cancer patient education, today announce a new strategic alliance. , As ...
Breaking Medicine News(10 mins):
(Date:10/2/2017)... Oct. 2, 2017 The Rebound mobile app is ... to reverse the tide of prescription drug addiction. The app ... medicine intake and stepping down their dosage in a safe, ... in December 2017; the first 100,000 people to sign up ... http://www.rebound-solution.com/ ...
(Date:9/27/2017)... NEW YORK , Sept. 27, 2017  DarioHealth Corp. (NASDAQ: DRIO), ... solutions, today announced that its MyDario product is expected to appear on ... for when The Dr. Oz Show airs in your area: http://www.doctoroz.com/page/where-watch-dr-oz-show ... The nine-time Emmy award-winning, The Dr. ... ...
(Date:9/22/2017)... -- As the latest Obamacare repeal effort moves is debated, ... and Lindsey Graham (R-SC) medical device market ... is in an odd place.  The industry wants repeal ... on medical device sales passed along with the Affordable ... visits and hospital customers with the funding to invest ...
Breaking Medicine Technology: