Navigation Links
Alcoholism-associated molecular adaptations in brain neurocognitive circuits
Date:7/8/2008

After many years of heavy drinking, alcohol produces pathological alterations in the brain. In many alcoholics these changes culminate in massive social deterioration and disorders of memory and learning. Severe cognitive impairments occur in approximately 10% of heavy drinkers. Alcoholic dementia is the second leading course of adult dementia in the Western countries, accounting for 10% of the cases, and still represents an unresolved problem. So far no effective pharmacotherapy for memory problems in alcoholics is available.

Nowadays this problem can be approached by innovative research using molecular and epigenetic analyses, which yield new insight into brain pathophysiology. Molecular dysregulations in endogenous opioids a neurotransmitter system in the brain that is central to reward function and pain control are supposed to play a critical role in the development of alcoholism and associated cognitive impairment.

Professor Georgy Bakalkin, involved in a research team focusing on biochemical mechanisms underlying neuropsychiatric disorders, will highlight the latest findings on this clinical challenge and presents a novel mechanism and understanding of cognitive deficit in human alcoholics. Thereby an emerging concept that proposes a new target for pharmacotherapy will be discussed, which might lead to innovative therapeutic interventions to improve or prevent alcohol-induced cognitive impairment in patients with alcohol dependence, and may be generalized to other learning and memory disorders.


'/>"/>

Contact: Sonja Mak
s.mak@update.europe.at
43-140-55734
European College of Neuropsychopharmacology
Source:Eurekalert

Page: 1

Related medicine news :

1. Schizophrenia linked to dysfunction in molecular brain pathway activated by marijuana
2. New research sheds light on the molecular basis of crib death
3. Solis Womens Health Brings Molecular Breast Imaging to Dallas-Fort Worth Metroplex
4. New Molecular Trigger Described for Hypertension, Diabetes
5. New molecular insight into amboebic dysentery
6. Molecular insight begins Trofex Phase 1 trial for detection of metastatic prostate cancer
7. Molecular insight begins Trofex Ph. 1 trial for detection of metastatic prostate cancer
8. Siemens Showcases Innovative Leadership in Molecular Imaging at SNM 2008
9. Xceed Molecular Licenses Signature from Moffitt Cancer Center and Adds Moffitt to Strategic Collaborator Program
10. DiagnoCures molecular diagnostic tests - PCA3 and GCC - discussed at scientific meetings
11. Research reveals molecular fingerprint of cocaine addiction
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:1/23/2017)... Portland, Oregon (PRWEB) , ... January 23, 2017 ... ... systems, announced today it has earned organic certification under the USDA National Organic ... the USDA Organic Certification process, we have established organic production and handling systems ...
(Date:1/23/2017)... ... January 23, 2017 , ... ... the American Society of Anesthesiologists® (ASA®), the Foundation for Anesthesia Education and ... Orthopaedic Surgeons (AAOS) and the Cigna Foundation, encourages proposals supporting high quality ...
(Date:1/23/2017)... ... ... “Crossing the Bar”: a moving and eloquent drama depicting the events ... is the creation of published author, Charlotte Hotte, a North Carolina native, a mother ... of the book to her sister, Denise, wishes to acknowledge her savior, Jesus Christ, ...
(Date:1/23/2017)... ... 23, 2017 , ... “Some Infallible Characteristics of Christ”: a fascinating and ... Christ” is the creation of published author, Rev. Dr. Robert W. Thomas, the third ... a preacher for over nineteen, a pastor for over fifteen years. He is a ...
(Date:1/22/2017)... ... January 22, 2017 , ... Zifam Pinnacle, an Australian company dedicated ... met with big-name retail buyers at the January ECRM Trade Show in Hilton Head, ... the utmost safety standards in all of its creations to help create a more ...
Breaking Medicine News(10 mins):
(Date:1/20/2017)... January 20, 2017 Stock-Callers.com today evaluates ... SGYP ), Novo Nordisk A/S (NYSE: NVO ... Pernix Therapeutics Holdings Inc. (NASDAQ: PTX ). These ... January 19 th , 2017, finishing near its session lows. ... dropped over 0.7%, while shares of health care companies in ...
(Date:1/20/2017)... , VAE, January 20, 2017 ... gestiegenen Bedarf an Nothilfe   Die internationale humanitäre ... für Hilfsgüter zu schaffen   Seine ... Premierminister der VAE sowie Herrscher von Dubai ... internationalen Stadt der Hilfe (International Humanitarian City IHC) zu ...
(Date:1/19/2017)... Jan. 19, 2017 Report Details ... Which areas are going to grow at the fastest ... 2026, assessing data, trends, opportunities and prospects. Our ... the most lucrative areas in the industry and the ... forecasted sales across the all the major categories of ...
Breaking Medicine Technology: