Navigation Links
Alcohol 'flush' signals increased cancer risk among East Asians
Date:3/23/2009

Many people of East Asian descent possess an enzyme deficiency that causes their skin to redden, or flush, when they drink alcohol. Scientists from the National Institute on Alcohol Abuse and Alcoholism (NIAAA) and Japan's Kurihama Alcohol Center now caution that heavy alcohol consumption greatly increases the risk for esophageal cancer among such individuals, who comprise about 8 percent of the world's population. Their review of recent research on this topic appears in the March 24, 2009 issue of PLoS Medicine. NIAAA is part of the National Institutes of Health.

"It is very important for clinicians who treat patients of East Asian descent to be aware of the risk of esophageal cancer from alcohol consumption in their patients who exhibit the alcohol flushing response, so they can counsel them about limiting their drinking," says NIAAA Acting Director Kenneth R. Warren, Ph.D.

First author Philip J. Brooks, Ph.D., of NIAAA's Laboratory of Neurogenetics, and his colleagues note that a clinician can reliably determine whether a patient is at risk simply by asking about previous episodes of facial flushing after drinking alcohol. Considered from this perspective, the authors point out, the flushing response is a clinically useful biomarker of genetic susceptibility to esophageal cancer risk from alcohol.

Dr. Brooks cites the high mortality from esophageal cancer and the large number of individuals with the deficient enzyme, known as aldehyde dehydrogenase 2 (ALDH2).

"Cancer of the esophagus is particularly deadly, with five-year survival rates ranging from 12 to 31 percent throughout the world. And we estimate that at least 540 million people have this alcohol-related increased risk for esophageal cancer," he notes. "We hope that, by raising awareness of this important public health problem, affected individuals who drink will reduce their cancer risk by limiting their alcohol consumption."

Dr. Brooks and hi
'/>"/>

Contact: NIAAA Press Office
niaaapressoffice@mail.nih.gov
301-443-3860
NIH/National Institute on Alcohol Abuse and Alcoholism
Source:Eurekalert

Page: 1 2 3

Related medicine news :

1. High alcohol consumption increases stroke risk among Chinese men
2. High alcohol consumption increases stroke risk, Tulane study says
3. Alcoholics With Cirrhosis Have More Brain Damage
4. Middle School Marks Most Critical Time to Start Ongoing Conversations About Drug and Alcohol Use With Kids
5. Recovery Resources Collaborates with Two Nonprofit Agencies for Children of Alcoholics Outreach Program
6. Frequent alcohol consumption increases cancer risk in older women
7. Family history of alcoholism affects response to drug used to treat heavy drinking
8. Alcohol and cancer: is drinking the new smoking?
9. Kaiser Permanente study: Alcohol amount, not type -- wine, beer, liquor -- triggers breast cancer
10. Kaiser Permanente Study Shows Alcohol Consumption - No Matter Beverage Type - Linked to Breast Cancer Risk
11. Hands2GO(R) Hand Sanitizer Offers Alcohol-Free Alternative to Stopping the Spread of Flu at School and Work
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:5/24/2015)... 24, 2015 Scientists with Cardno ChemRisk, ... air quality compliance issues that may have raised the ... Mesothelioma has just posted an article on the research. ... The group found airborne asbestos levels well above OSHA ... 1984 and 2011. , “Asbestos compliance sampling data associated ...
(Date:5/24/2015)... Medicx Media Solutions http://www.medicxmedia.com ... Krihak as its head of programmatic strategy and ... expertise and leadership position in the data driven ... , Krihak is an experienced, award-winning agency and ... sales planning teams for mobile platform Jumptap. ...
(Date:5/23/2015)... 23, 2015 Dr. David Benvenuti, an experienced ... posted a new article to his website that ... Dr Benvenuti explained in the fascinating blog, he has ... their earlobes. , Known as “gauging,” the technique involves placing ... Dr. Benvenuti said will eventually stretch the holes out to ...
(Date:5/23/2015)... A live auction will be held to sell over ... other medical facilities around the United States. Various types ... anesthesia, exam and much more. , The live auction ... starting at 9:00am CDT each day. The equipment is at ... Park, IL 60160. Anyone can participate in the auction ...
(Date:5/22/2015)... May 22, 2015 Pioneer Millworks, the ... the forefront of designing with reclaimed wood, introducing their ... Los Angeles, California. Their newest offerings, Vat 35, ... surface and color to America's largest design event. , ... at each show, anxious to see and feel the ...
Breaking Medicine News(10 mins):Health News:New Analysis Finds Too Many Employers Ignored OSHA Asbestos Guidelines, According to Surviving Mesothelioma 2Health News:Medicx Media Solutions Expands Executive Team 2Health News:Dr. Benvenuti, a Plastic Surgeon in Newport Beach, CA, Posts New Article about Repairing Ear Gauges 2Health News:Over 5,200 Lots of Medical Equipment Will Be Sold by Live Auction 2Health News:Pioneer Millworks to Reveal New Design Trends with Reclaimed Wood at Dwell on Design in LA 2Health News:Pioneer Millworks to Reveal New Design Trends with Reclaimed Wood at Dwell on Design in LA 3
... been conducted to explore the relationship between bicycle riding ... not a causal relationship existed between bicycle riding on ... it is now necessary to shift the focus on ... field. , ,Dr. Schrader's research in 2002 reported ...
... Dengue has claimed four lives in a week in Kolkata, ... Chief Prabhakar Chatterjee has admitted that the fever that swept ... brain fever., ,There have been reports of 4 casualties ... eight other people. The unofficial death toll is seven., ...
... to daily kill a few more people in Uttar Pradesh ... Nepal., ,In this special report we review encephalitis or ... essential information on its history, its spread, its life cycle ... of Japanese encephalitis occurred during the “summer encephalitis” outbreaks in ...
... compromising with the life of its patients and selling expired ... The criminal operation was brought to light // by ... camera. , ,As soon as the accusation was made ... caught. But with evidence staring them in the face they ...
... Indian Pharmaceuticals companies Glenmark pharma and Nicholas Piramal has ... USFDA ban the sale of Valdecoxib formulation products and ... of the government of India asking the pharma companies ... already withdrew the drug from the market after the ...
... School had provided a guideline for the psychotherapists as ... from dropping out of therapy sessions., ,Surveys show ... psychotherapy quit, dissatisfied, against the recommendation of their therapist. ... and, in group therapy, for other group members. , ...
Cached Medicine News:Health News:Brain Fever or Encephalitis Spreading in North India 2Health News:Quitting Psychotherapy Midway May Be Preventable 2
(Date:5/22/2015)... , May 22, 2015 The leading ... $13 billion global cardiac rhythm management device market ... found that Medtronic, St. Jude Medical, Boston Scientific ... of this market segment. The healthcare market research ... , uses 2015 as a base year, providing ...
(Date:5/22/2015)... OF PRUSSIA, Pa. , May 22, 2015  The ... Behring its 2015 Corporate Leadership Award as recognition for ... improving the care of the bleeding disorders community.  The award ... Director, CSL Limited, during the NHF Annual Spring Soiree in ... "The National Hemophilia Foundation is dedicated to finding ...
(Date:5/22/2015)... May 20, 2015 Research and Markets( ... "Guide to Prepare Application Dossiers for Oversea ... Edition) " report to their offering. ... of segment market of the most growth potentiality, ... device manufacturers and producers to penetrate such market. ...
Breaking Medicine Technology:Kalorama: Top Companies Dominate Cardiac Defibrillator Market 2Kalorama: Top Companies Dominate Cardiac Defibrillator Market 3Kalorama: Top Companies Dominate Cardiac Defibrillator Market 4National Hemophilia Foundation Honors CSL Behring with Corporate Leadership Award 2National Hemophilia Foundation Honors CSL Behring with Corporate Leadership Award 3National Hemophilia Foundation Honors CSL Behring with Corporate Leadership Award 4China Guide to Prepare Application Dossiers for Oversea Medical Device Registration and Recordation 2China Guide to Prepare Application Dossiers for Oversea Medical Device Registration and Recordation 3
... YORK, Feb. 23, 2011 Reportlinker.com announces that a ... Global Prepackaged Medical Kits and Trays ... This report analyzes the worldwide markets for Prepackaged ... following Product Segments: ENT Custom Trays, Ophthalmic Custom Trays, ...
... that a new market research report is available in ... Industry http://www.reportlinker.com/p087375/Global-Pain-Management-Industry.html ... Management in US$ Million by the following product segments: ... Services. The report provides separate comprehensive analytics for the ...
Cached Medicine Technology:Reportlinker Adds Global Prepackaged Medical Kits and Trays Industry 2Reportlinker Adds Global Pain Management Industry 2
The Model 340DT is a new desk top pulse oximeter that was designed for continuous pulse oximetry and has visual and audible alarms to aid with patient monitoring....
The Model 305 is a hand-held, portable, lightweight oximeter designed for spot checking. It has a NiCad rechargeable battery....
... Model 130 has expanded memory capabilities for overnight ... to retain oxygen saturation and pulse rate data, ... best suit your needs:, ,1. The Model ... information for a single patient, making the device ...
... After inserting a finger into comfortable ... on, and continuous measurement is performed., ... character height. In darker surroundings, back ... reading., ,Light weight, compact contour ...
Medicine Products: