Navigation Links
Alcohol could intensify the effects of some drugs in the body
Date:7/26/2012

Scientists are reporting another reason besides possible liver damage, stomach bleeding and other side effects to avoid drinking alcohol while taking certain medicines. Their report in ACS' journal Molecular Pharmaceutics describes laboratory experiments in which alcohol made several medications up to three times more available to the body, effectively tripling the original dose.

Christel Bergstrm and colleagues explain that beverage alcohol, or ethanol, can cause an increase in the amount of non-prescription and prescription drugs that are "available" to the body after taking a specific dose. Alcohol can change how enzymes and other substances in the body interact with many of the 5,000 such medications on the market. Some of these medications don't dissolve well in the gastrointestinal tract especially in the stomach and intestines. The researchers sought to test whether ethanol made these drugs dissolve more easily. If so, this would make the drugs more available in the body, possibly intensifying their effects when combined with alcohol.

To find out, the scientists used a simulated environment of the small intestine to test how rapidly medications dissolved when alcohol was and was not present. Almost 60 percent of the 22 medications in their tests dissolved much faster in the presence of alcohol. In addition, they found that certain types of substances, such as those that were acidic, were more affected. Some common acidic drugs include warfarin, the anticoagulant; Tamoxifen, used to treat certain forms of cancer; and naproxen, which relieves pain and inflammation.


'/>"/>

Contact: Michael Bernstein
m_bernstein@acs.org
202-872-6042
American Chemical Society
Source:Eurekalert

Page: 1

Related medicine news :

1. Study links alcohol/energy drink mixes with casual, risky sex
2. The Health Benefits, and Risks, of Alcohol
3. Alcohol Poses Serious Risks for Those With Diabetes
4. Moderate alcohol intake is associated with a lower risk of kidney cancer
5. Alcohol May Not Be Kind to the Aging Brain
6. Alcohol problems account for a quarter of Scottish intensive care unit admissions
7. New study suggests moderate alcohol consumption may help prevent bone loss
8. Oral contraceptive use in girls and alcohol consumption in boys are associated with increased BP....
9. 40 Million Americans Addicted to Cigarettes, Alcohol or Drugs
10. Whats the best way to treat problem alcohol use?
11. Limited amounts of alcohol during pregnancy do not harm children
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:4/29/2016)... ... 29, 2016 , ... Reltok Nasal Products proudly announces that Boston Medical Products, ... nose and throat specialty, has added the KOTLER NASAL AIRWAY™ to its diverse product ... a newly patented safety device secured by nasal surgeons onto the floor of the ...
(Date:4/29/2016)... ... April 29, 2016 , ... ... media enterprise focused entirely on patients with cancer, today announced that Lynne Malestic, ... as the 2016 CURE® Extraordinary Healer® for Oncology Nursing , which honors ...
(Date:4/29/2016)... (PRWEB) , ... April 29, 2016 , ... ... and hospice software, outsourced billing and coding services, and Deyta Analytics, recently announced ... hospices providing the highest level of quality as measured from the caregiver’s point ...
(Date:4/29/2016)... ... April 29, 2016 , ... Pro3rd Grunge is a ... Film Studios’ lower thirds to introduce people, characters, and locations without having to set ... lines, accents, textures and many more design components. Simply select a preset and drag ...
(Date:4/28/2016)... ... 2016 , ... Monthly subscription boxes are all the rage, and "My Subscription ... the ZEN BOX , the aromatherapy subscription box. , ZEN BOX delivers three new ... frankincense) and one Zen Blend (like immune boost, sublime sleep or de-stress blends) ...
Breaking Medicine News(10 mins):
(Date:4/28/2016)... 2016 Dr. Vivek Ahuja , ... Ste phen Schmidt ... provider of cloud-based software solutions for life sciences, today announced key ... a wealth of insight to a growing business.  This will bolster ... George Phillips joined ArisGlobal in the position of Vice ...
(Date:4/28/2016)... , April 28, 2016 ... H1 2016" is a report that provides an ... strengthen R&D pipelines by identifying new targets and ... Company Profiles discussed in this H1 2016 ... Riunite Srl, AbbVie Inc., Abiogen Pharma S.p.A., Ablynx ...
(Date:4/27/2016)... TURIN, Italy , April 27, 2016 ... MR-guided linear accelerator (MR-linac) platform will be the focal ... annual meeting of the European Society for Radiotherapy & ... Elekta,s MR-linac integrates a state-of-the-art radiotherapy system and ... a physician to clearly see the patient,s anatomy in ...
Breaking Medicine Technology: