Navigation Links
Air pollution alters immune function, worsens asthma symptoms
Date:10/5/2010

Berkeley Exposure to dirty air is linked to decreased function of a gene that appears to increase the severity of asthma in children, according to a joint study by researchers at Stanford University and the University of California, Berkeley.

While air pollution is known to be a source of immediate inflammation, this new study provides one of the first pieces of direct evidence that explains how some ambient air pollutants could have long-term effects.

The findings, published in the October 2010 issue of the Journal of Allergy and Clinical Immunology, come from a study of 181 children with and without asthma in the California cities of Fresno and Palo Alto.

The researchers found that air pollution exposure suppressed the immune system's regulatory T cells (Treg), and that the decreased level of Treg function was linked to greater severity of asthma symptoms and lower lung capacity. Treg cells are responsible for putting the brakes on the immune system so that it doesn't react to non-pathogenic substances in the body that are associated with allergy and asthma. When Treg function is low, the cells fail to block the inflammatory responses that are the hallmark of asthma symptoms.

The findings have potential implications for altered birth outcomes associated with polluted air, much the same as those noted for the effects of cigarette smoke.

"When it came out that cigarettes can cause molecular changes, it meant the possibility that mothers who smoked could affect the DNA of their children during fetal development," said study lead author Dr. Kari Nadeau, pediatrician at Stanford's Lucile Packard Children's Hospital and an assistant professor of allergy and immunology at Stanford's School of Medicine. "Similarly, these new findings suggest the possibility of an inheritable effect from environmental pollution."

Forty-one participants came from the Fresno Asthmatic Children's Environment Study (FACES
'/>"/>

Contact: Sarah Yang
scyang@berkeley.edu
510-643-7741
University of California -- Berkeley
Source:Eurekalert

Page: 1 2 3

Related medicine news :

1. Years of Exposure to Traffic Pollution Raises Blood Pressure
2. Air Pollution Slows Womens Marathon Times
3. Whats Cookin? It Could Be Air Pollution
4. Hear the World Survey Reveals Growing Noise Pollution Affecting both Physical and Mental Health
5. Air Pollution Raises Risk of Heart Disease, Death
6. Revised Oil Pollution Act Case Digest and Source Book to be Published June 2, 2010
7. Revised Edition of the Oil Pollution Act Case Digest and Source Book Released
8. Air Pollution Tied to Breathing Problems in Sleep
9. Studies confirm presence, severity of pollution in national parks
10. New map offers a global view of health-sapping air pollution
11. Using new approach, Mayo Clinic researchers find level of gene alters risk of Alzheimers disease
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:7/29/2014)... LEBANON, NH (July 29, 2014) Using quality improvement ... Northern New England Cardiovascular Disease Study Group, researchers have ... undergoing a procedure with contrast dye. , Currently, 7-15 ... procedure with contrast-dye end up with kidney injury, which ... function leading to temporary or permanent dialysis, says a ...
(Date:7/29/2014)... Historically, Memorial Day kicks off a ... celebrated throughout that time by picnics, barbecues and beach ... mark the start of a period that will witness ... In 2012 nearly 1.000 people were killed in crashes ... to Labor Day. , The summer's warmer weather, longer ...
(Date:7/29/2014)... (PRWEB) July 29, 2014 During his 37 ... Bruce, DMD & Associates, has had a steady stream of ... dentistry. These students have now gone on to dental school ... proving that the shadowing program helps college students find success. ... Bruce has given them the chance to see a realistic ...
(Date:7/29/2014)... A team of scientists, led by ... has developed a blood test for Alzheimer’s disease risk ... of Alzheimer’s disease interventions, according to an article published ... and this study represents one of several pieces that ... couple of years,” Ethell said. , The study, “Women ...
(Date:7/29/2014)... July 29, 2014 Just months after ... to 4 new states, the exciting FX family does ... and one time farmboy from Arkansas, is shocking the ... innovative event technologies to the masses. This time ... packed island of Jamaica. This new office is ...
Breaking Medicine News(10 mins):Health News:Reducing kidney injury using a quality improvement method 2Health News:Narconon New Life Retreat Launches New Alcohol Prevention Program 2Health News:Arthur Bruce Dental Helps College Students 2Health News:Professor Develops Blood Test for Alzheimer’s Disease Risk 2Health News:Atlanta Special FX Rapidly Expanding Just Opens First International Corporate Office in Jamaica 2
... to Ensure Equitable Protections,for All Americans and Their ... America,s,Health (TFAH) issued the following statement on the ... Services(HHS) Draft Guidances to Assist in,Preparation for an ... government must do all it can to ensure ...
... Cadence Pharmaceuticals,Inc. (Nasdaq: CADX ), a ... product candidates principally,for use in the hospital setting, ... Schroeder will present the corporate overview on,Wednesday, June ... pm Pacific Time),during the Seventh Annual Needham & ...
... DALLAS, June 4 The echocardiography lab ... by the,Inter-societal Commission for the Accreditation of ... two hospitals in the region,accredited by the ... is paramount," said Dr.,Jorge Cheirif, Presbyterian,s chief ...
... abuse after college as well as face ... College students with a "dense" family history of alcoholism ... study says. , While most university students tend to ... young adults, some develop alcohol-use disorders, or AUDs. Most ...
... participants saw urine protein levels lowered significantly , , WEDNESDAY, June ... to combat some of the damaging effects of type 2 ... a new Danish study has found. , But ... and aliskiren (Tekturna) to block the activity of a molecule ...
... progress among Hispanic children , , WEDNESDAY, June 4 (HealthDay ... to engage in risky health behaviors, including sexual intercourse, ... U.S. health officials said Wednesday. , While there have ... students, Hispanic students remain at higher risk for some ...
Cached Medicine News:Health News:Trust for America's Health on New HHS Influenza Pandemic Draft Guidance 2Health News:Cadence Pharmaceuticals' CEO Theodore Schroeder to Present at the Seventh Annual Needham & Company, LLC Biotechnology and Medical Technology Conference on June 11, 2008 in New York 2Health News:Echocardiography Lab at Presbyterian Hospital of Dallas Achieves Prestigious Reaccreditation 2Health News:Family History of Alcoholism Puts Student Drinkers at Risk 2Health News:Two-Drug Combo Reduces Diabetic Kidney Damage 2Health News:Two-Drug Combo Reduces Diabetic Kidney Damage 3Health News:Fewer U.S. High School Students Engage in Risky Behaviors 2Health News:Fewer U.S. High School Students Engage in Risky Behaviors 3
(Date:7/29/2014)... 29, 2014  Alexza Pharmaceuticals, Inc. (Nasdaq: ... two healthcare conferences during the third quarter, the 2014 ... Global Healthcare 2014 Conference.  Alexza,s corporate presentation will be ... on each event are below: , 2014 ... in Boston , MA.  The format ...
(Date:7/29/2014)... -- Edwards Lifesciences Corporation (NYSE: EW ), the ... monitoring, today reported net income for the quarter ended June ... and non-GAAP net income of $94.0 million, or $0.88 per ... earlier was $93.3 million, or $0.81 per diluted share, and ... share.  Net sales for the quarter ended ...
(Date:7/29/2014)... 29, 2014 New high priced hepatitis C ... by a projected $2.9 to $5.8 billion next year, ... Milliman released today by the Pharmaceutical Care Management Association ... increase by as much as 8.6 percent in 2015 ... Sovaldi and Olysio. The study finds that ...
Breaking Medicine Technology:Alexza Pharmaceuticals Announces Participation in Upcoming Investor Conferences 2Alexza Pharmaceuticals Announces Participation in Upcoming Investor Conferences 3Edwards Lifesciences Reports Strong Second Quarter Results 2Edwards Lifesciences Reports Strong Second Quarter Results 3Edwards Lifesciences Reports Strong Second Quarter Results 4Edwards Lifesciences Reports Strong Second Quarter Results 5Edwards Lifesciences Reports Strong Second Quarter Results 6Edwards Lifesciences Reports Strong Second Quarter Results 7Edwards Lifesciences Reports Strong Second Quarter Results 8Edwards Lifesciences Reports Strong Second Quarter Results 9Edwards Lifesciences Reports Strong Second Quarter Results 10Edwards Lifesciences Reports Strong Second Quarter Results 11Edwards Lifesciences Reports Strong Second Quarter Results 12Edwards Lifesciences Reports Strong Second Quarter Results 13Edwards Lifesciences Reports Strong Second Quarter Results 14Edwards Lifesciences Reports Strong Second Quarter Results 15Edwards Lifesciences Reports Strong Second Quarter Results 16Edwards Lifesciences Reports Strong Second Quarter Results 17Edwards Lifesciences Reports Strong Second Quarter Results 18Edwards Lifesciences Reports Strong Second Quarter Results 19Edwards Lifesciences Reports Strong Second Quarter Results 20Edwards Lifesciences Reports Strong Second Quarter Results 21Edwards Lifesciences Reports Strong Second Quarter Results 22Edwards Lifesciences Reports Strong Second Quarter Results 23Edwards Lifesciences Reports Strong Second Quarter Results 24Edwards Lifesciences Reports Strong Second Quarter Results 25New Milliman Study: Hepatitis C Drugs Could Increase Medicare Part D Spending by $2.9 to $5.8 Billion in 2015 2
... GTHR.PK), announces it will soon begin offering its Real Time,PCR ... , GeneThera is set ... January of 2009. According to GeneThera Chairman, Dr. Tony ... PCR test for Johne,s disease,called HerdGuard(TM) by the first of ...
... A new cancer treatment is,realizing outstanding results against ... large, stage 4 tumor was reduced in size ... no longer could be definitely,identified on scans. Pancreatic ... diagnosis. NeoPlas Innovation,s combination of FDA-approved drugs,appears to ...
Cached Medicine Technology:GeneThera Announces it is Set to Begin Commercial Testing for Johne's Disease as Soon as January, 2009. 2GeneThera Announces it is Set to Begin Commercial Testing for Johne's Disease as Soon as January, 2009. 3GeneThera Announces it is Set to Begin Commercial Testing for Johne's Disease as Soon as January, 2009. 4New Cancer Treatment Shrinks Pancreatic Tumor 2
... The National Laboratory Training Network (NLTN) ... Association of Public Health Laboratories (APHL) and ... (CDC). NLTN provides cost-effective training in a ... resources, including a FREE Lending Library. Log ...
... The AAFP-PT Laboratory Proficiency Testing and Quality ... are designed to assist POLs, clinics and ... designed to assure accuracy of patient lab ... requirements. Participation provides the opportunity to earn ...
An indirect immunofluorescence (IFA) antibody test for the detection and semiquantitation of anti-glomerular basement membrane (GBM) antibodies in human serum. Slide Detail: 6-well Monkey Kidney Subs...
An enzyme linked immunosorbant assay (ELISA) for the detection and quantitation of Rheumatoid Factor (RF) of IgM isotype in human serum....
Medicine Products: