Navigation Links
Air Pollution May Cause Appendicitis: Study
Date:10/5/2009

Researchers say cases go up in the warm-weather months when ozone is highest

MONDAY, Oct. 5 (HealthDay News) -- Air pollution is already linked to respiratory and cardiovascular ills, and now researchers say the dirty air you breathe may also cause appendicitis.

Authors of a new study published in the Oct. 5 issue of the Canadian Medical Association Journal found that cases of appendicitis go up when the air is dirtier.

"This makes us think about the underlying cause of appendicitis that could potentially be linked to air pollution," said Dr. Gilaad G. Kaplan, senior author of the study and assistant professor of medicine in the division of gastroenterology at the University of Calgary in Alberta. "Air pollution is a modifiable risk factor. If these findings are confirmed and we are able to legislate better air pollution control, cleaner air, then potentially we could prevent more cases of appendicitis."

But at this early point in the research, the implications are not so clear-cut, warned another expert.

"It's provocative, but there's a huge difference between correlating any number of factors with a disease and proving that any of these factors might actually cause a disease, and this study fails to show causation," said Dr. F. Paul Buckley III, assistant professor of surgery at the Texas A&M Health Science Center College of Medicine and a surgeon at Scott & White Healthcare Round Rock, Texas.

"Do we all want to decrease pollution? Yes. Is that going to decrease the incidence of appendicitis? I doubt it," said Buckley.

Parts of the findings were presented at a conference a year ago.

No one really knows why appendicitis, or swelling and infection of the appendix, occurs.

Appendicitis cases rose significantly in the late 19th century and early 20th century, as industrialization took hold. Cases declined in the middle and later parts of the last century, at about the time clean air legislation gained headway. Meanwhile, countries that are just now industrializing have increasing rates of the condition, the study authors stated.

A prevailing theory is that appendicitis occurs when the opening to the appendix, a pouch-like organ attached to the large intestine, gets blocked. Specifically, some experts believe that lower fiber intake among citizens of industrialized countries leads to obstruction of the appendix by the stool.

But that doesn't explain the decreased incidence of appendicitis in the second half of the 20th century, Kaplan said.

Air pollution is already linked with a wide range of health conditions, most notably respiratory diseases and cardiovascular disease, including heart attack and stroke.

Kaplan and his colleagues looked at more than 5,000 adults who were hospitalized in Calgary with appendicitis between April 1, 1999, and the end of 2006. This data was cross-referenced with an analysis of air pollutants the week prior to the admissions.

"We found that individuals were more likely to come in with appendicitis in weeks with higher concentrations of air pollutants, specifically ozone and nitrogen dioxide," Kaplan said.

More appendicitis admissions took place during Canada's warmest months (April through September, when people are more likely to be outdoors), and men seemed more likely to be affected by air pollutants than women. It's unclear why this gender difference exists, the researchers said.

Kaplan theorizes that inflammation may explain the link -- if it proves to exist -- between air quality and appendicitis.

"It's speculative, but air pollution might be driving inflammation which triggers appendicitis," he said. "We're a few steps away before we can make that statement. We need to confirm and replicate these findings."

Kaplan and his co-authors plan more studies in multiple cities in Canada.

Last year, Forbes magazine rated Calgary as the world's cleanest city and Baku, Azerbaijan, as the dirtiest.

More information

The U.S. National Institutes of Health has more on appendicitis.



SOURCES: Gilaad G. Kaplan, M.D., assistant professor of medicine, division of gastroenterology, University of Calgary, Alberta; F. Paul Buckley III, M.D., assistant professor of surgery, Texas A&M Health Science Center College of Medicine, and surgeon, Scott & White Healthcare Round Rock, Texas; Oct. 5, 2009, Canadian Medical Association Journal


'/>"/>
Copyright©2009 ScoutNews,LLC.
All rights reserved

Related medicine news :

1. Air Pollution May Raise Blood Pressure
2. Ampac Fine Chemicals LLC Recognized for Voluntarily Reducing Pollution
3. Oakland Port Commission Seeks Resolution to Allow Local Officials Real Power to Clean Up Diesel Truck Pollution; Improve Security, Safety
4. Acoustiblok, Inc. Combines Sound Abatement and Insulation Materials at Broward County Waste to Energy Plant to Reduce Industrial Noise Pollution
5. Latest trinational report presents most complete picture of North American industrial pollution
6. Environmental pollution increases the risk of liver disease
7. Short-Term Air Pollution Exposure May Damage DNA
8. Air Pollution Exposure May Slow Fetal Growth
9. Ozone Pollution Taking Toll on American Lives
10. Environmental Defense Fund Welcomes EPA Clean Air Standards to Reduce Hazardous Diesel Pollution
11. Prenatal Exposure to Traffic Pollution May Lead to Asthma
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:10/13/2017)... ... October 13, 2017 , ... Many families have long-term insurance that covers ... companies have a waiver for care if the client has a cognitive impairment diagnosis. ... pays for care, is often waived, so the benefits from their insurance start immediately,” ...
(Date:10/13/2017)... ... October 13, 2017 , ... Yisrayl Hawkins, Pastor and Overseer at ... of the most popular and least understood books in the Holy Scriptures, Revelation. The ... that have baffled scholars for centuries. Many have tossed it off as mere rubbish, ...
(Date:10/13/2017)... ... October 13, 2017 , ... “America On The Brink”: ... “America On The Brink” is the creation of published author, William Nowers. ... As a WWII veteran, he spent thirty years in the Navy. Following ...
(Date:10/12/2017)... ... October 12, 2017 , ... The company ... of today’s consumer and regulatory authorities worldwide. From Children’s to Adults 50+, every ... meet the highest standard. , These products are also: Gluten Free, Non-GMO, ...
(Date:10/12/2017)... ... 12, 2017 , ... Information about the technology: , Otomagnetics ... enable prevention of a major side effect of chemotherapy in children. Cisplatin and ... For cisplatin, hearing loss is FDA listed on-label as a dose limiting toxicity. ...
Breaking Medicine News(10 mins):
(Date:10/11/2017)... IRVING, Texas , Oct. 11, 2017  Caris ... science focused on fulfilling the promise of precision medicine, ... Institute has joined Caris, Precision Oncology Alliance™ (POA) as ... leading cancer centers, the St. Jude Crosson Cancer Institute ... to advance the use of tumor profiling, making cancer ...
(Date:10/10/2017)... 2017   West Pharmaceutical Services, Inc. (NYSE: ... drug administration, today shared the results of a study ... the intradermal administration of polio vaccines. The study results ... May 2017 by Dr. Ondrej Mach , Clinical ... Organization (WHO), and recently published in the journal ...
(Date:10/4/2017)... the Centers for Disease Control and Prevention (CDC), influenza vaccination should ... helping communities across Massachusetts , Connecticut ... shots through the end of the month. *Some exclusions apply ... ... is by the end of October, according to the Centers for Disease ...
Breaking Medicine Technology: