Navigation Links
Aging of Blood Stem Cells May Be Reversible
Date:1/27/2010

Older mice 'rejuvenated' when treated with blood factors from younger mice, researchers found

WEDNESDAY, Jan. 27 (HealthDay News) -- Scientists have found a way to make old stem cells in the blood act like young stem cells, a discovery that could lead to ways to slow the aging process.

Taking certain factors from the blood of young mice and putting them in old mice made old stem cells take on the characteristics of younger stem cells. In addition, the tissues of the older mice appeared much more "youthful," according to the Harvard Stem Cell Institute researchers at the Joslin Diabetes Center.

The change in the older stem cells is driven by signals from another type of cell nearby in the bone, the researchers explained. They added that this finding improves understanding of aging of the blood-forming system and points toward blood-based treatments for age-related health problems.

The study findings are published in the Jan. 27 issue of the journal Nature.

"What's most exciting is that the changes that occur in blood stem cells during aging are reversible, through signals carried by the blood itself. This means that the blood system offers a potential therapeutic avenue for age-related stem cell dysfunction," Amy J. Wagers, an associate professor in Harvard's Department of Stem Cell and Regenerative Biology, and an investigator at the Joslin Diabetes Center, said in a news release from the center.

The study doesn't directly address diabetes-related mechanisms but "there's more and more evidence of an overlap in the regulatory pathways that are implicated in aging and in type 2 diabetes," Wagers said.

More information

The U.S. National Institutes of Health has more about stem cells.



-- Robert Preidt



SOURCE: Joslin Diabetes Center, news release, Jan. 27, 2010


'/>"/>
Copyright©2010 ScoutNews,LLC.
All rights reserved

Related medicine news :

1. Stanford researchers find culprit in aging muscles that heal poorly
2. Brain imaging reveals breakdown of normal emotional processing
3. Clarity Imaging International, Inc. Rolls Out Mobile DEXA Program
4. Oncologists are critical in managing psychiatric disorders in patients with advanced cancer
5. Fry Construction Selected for High-Profile Medical Imaging Project
6. September is Healthy Aging Month
7. The era of global aging: GSAs annual meeting to present new research on hot topics in aging
8. Elbit Medical Imaging Ltd. Announces Publication of a Prospectus in Israel
9. U.S. Health Initiative Targets Aging Hispanics
10. Ultrasonix Adds Global Medical Imaging Into Its North American Sales Force
11. Imaging Software Helps Track, Treat Injured Brains
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:4/28/2016)... ... 2016 , ... Starting today, households across the United States ... Prescription Assistance Program. They are customized to reflect the specific health needs of ... ready-to-use, state-themed card and, in the near future, material that highlights savings on ...
(Date:4/28/2016)... (PRWEB) , ... April 28, 2016 , ... North ... care as soon as possible is essential when it comes to dental accidents or ... the difference between saving and losing a tooth. Toothaches, knocked-out teeth, chipped teeth, and ...
(Date:4/28/2016)... ... April 28, 2016 , ... For many, a diet is only as good as it looks. ... not look good. In addition, an individual cannot deny the importance of maintaining a healthy ... therefore, has worked to create a product range that could entice people to eat clean ...
(Date:4/28/2016)... ... 28, 2016 , ... Dr. Farhan Qureshi has recently added yet another high ... Rated Alexandria Dentist from Find Local Doctors . This recognition is ... sources. Find Local Doctors is an online directory that features these patient reviews, helping ...
(Date:4/28/2016)... , ... April 28, 2016 , ... In an effort ... destructive flooding, Dynamic Fitness has announced that it will donate $5.00 for every membership ... to the City of Houston Storm Recovery Fund: http://www.houstonemergency.org/go/doc/2263/2523430 ...
Breaking Medicine News(10 mins):
(Date:4/28/2016)... 28, 2016 Dr. Vivek Ahuja ... and Ste phen Schmidt ... leading provider of cloud-based software solutions for life sciences, today announced ... bring a wealth of insight to a growing business.  This will ... George Phillips joined ArisGlobal in the position of ...
(Date:4/28/2016)... TapImmune,Inc. (TPIV), a clinical-stage ... gene-based immunotherapeutics and vaccines for the treatment of cancer & ... 3rd Annual Growth Capital Expo to be held ... Caesars Palace in Las Vegas, Nevada.  The Company presentation ... th by Dr. John N. Bonfiglio a ...
(Date:4/27/2016)... Avril 2016   ... +5% sur le trimestre, soutenu par une croissance ... Croissance de +16% des ventes aux hôpitaux ... Kea Technologies (Euronext : MKEA, FR0010609263 ; OTCQX : MKEAY), inventeur ... aujourd,hui son chiffre d,affaires pour le premier trimestre ...
Breaking Medicine Technology: