Navigation Links
Aging of Blood Stem Cells May Be Reversible
Date:1/27/2010

Older mice 'rejuvenated' when treated with blood factors from younger mice, researchers found

WEDNESDAY, Jan. 27 (HealthDay News) -- Scientists have found a way to make old stem cells in the blood act like young stem cells, a discovery that could lead to ways to slow the aging process.

Taking certain factors from the blood of young mice and putting them in old mice made old stem cells take on the characteristics of younger stem cells. In addition, the tissues of the older mice appeared much more "youthful," according to the Harvard Stem Cell Institute researchers at the Joslin Diabetes Center.

The change in the older stem cells is driven by signals from another type of cell nearby in the bone, the researchers explained. They added that this finding improves understanding of aging of the blood-forming system and points toward blood-based treatments for age-related health problems.

The study findings are published in the Jan. 27 issue of the journal Nature.

"What's most exciting is that the changes that occur in blood stem cells during aging are reversible, through signals carried by the blood itself. This means that the blood system offers a potential therapeutic avenue for age-related stem cell dysfunction," Amy J. Wagers, an associate professor in Harvard's Department of Stem Cell and Regenerative Biology, and an investigator at the Joslin Diabetes Center, said in a news release from the center.

The study doesn't directly address diabetes-related mechanisms but "there's more and more evidence of an overlap in the regulatory pathways that are implicated in aging and in type 2 diabetes," Wagers said.

More information

The U.S. National Institutes of Health has more about stem cells.



-- Robert Preidt



SOURCE: Joslin Diabetes Center, news release, Jan. 27, 2010


'/>"/>
Copyright©2010 ScoutNews,LLC.
All rights reserved

Related medicine news :

1. Stanford researchers find culprit in aging muscles that heal poorly
2. Brain imaging reveals breakdown of normal emotional processing
3. Clarity Imaging International, Inc. Rolls Out Mobile DEXA Program
4. Oncologists are critical in managing psychiatric disorders in patients with advanced cancer
5. Fry Construction Selected for High-Profile Medical Imaging Project
6. September is Healthy Aging Month
7. The era of global aging: GSAs annual meeting to present new research on hot topics in aging
8. Elbit Medical Imaging Ltd. Announces Publication of a Prospectus in Israel
9. U.S. Health Initiative Targets Aging Hispanics
10. Ultrasonix Adds Global Medical Imaging Into Its North American Sales Force
11. Imaging Software Helps Track, Treat Injured Brains
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:5/31/2016)... ... 31, 2016 , ... Spartan Bioscience today introduced the Spartan ... convenience. , The Cube is exceptionally small—it takes up the space of a ... into any space, whether in a hospital, doctor’s office, or pharmacy. , The ...
(Date:5/31/2016)... ... May 31, 2016 , ... Like jewels in a crown, ... know – London is home to Ontario’s leading day spa and one of Canada’s ... Tamba began with a unique concept to combine spa services with hair and ...
(Date:5/31/2016)... ... ... In his latest video, renowned AstroNumerologist Jesse Kalsi reveals ... candidate Donald Trump as an example, Kalsi describes the way AstroNumerology conveys the ... numbers up,” says Kalsi. “It is about looking at each individual number, since ...
(Date:5/31/2016)... ... 31, 2016 , ... Interest is on the rise for using the CRISPR-Cas9 ... tool for RNAi hit validation. A key reason may be that high-throughput synthesis—combined with ... CRISPR RNA (crRNA) collections in arrayed formats. , Arrayed crRNA screens ...
(Date:5/31/2016)... ... , ... In a recent interview on The Greenburgh Report radio show hosted ... WVOX (1460 AM), leading medical insurance advocate Adria Goldman Gross discussed several eye-opening ... maelstrom.” , During the interview with Mr. Feiner that aired on May 7, ...
Breaking Medicine News(10 mins):
(Date:5/31/2016)... 2016 194 Mitgliedsstaaten ... Eliminierung von viraler Hepatitis    Am ... eingegangen, virale Hepatitis bis 2030 zu eliminieren. ... Assembly haben sich die Staaten einstimmig dafür entschieden, ... Viral Hepatitis Strategy) zu verabschieden, was das bisher ...
(Date:5/30/2016)... , May 30, 2016 ... "Healthcare Analytical Testing Services Market by Type (Stability, ... Services), by End User (Pharmaceutical Companies, Medical Device ... MarketsandMarkets, The market witnessed healthy growth during the ... a CAGR of 11.3% between 2016 and 2021 ...
(Date:5/30/2016)... , May 30, 2016 ... 2016" market research report with comprehensive information on ... comparative analysis at various stages, therapeutics assessment by ... administration (RoA) and molecule type, along with latest ... also reviews key players involved in the therapeutic ...
Breaking Medicine Technology: