Navigation Links
Aging of Blood Stem Cells May Be Reversible
Date:1/27/2010

Older mice 'rejuvenated' when treated with blood factors from younger mice, researchers found

WEDNESDAY, Jan. 27 (HealthDay News) -- Scientists have found a way to make old stem cells in the blood act like young stem cells, a discovery that could lead to ways to slow the aging process.

Taking certain factors from the blood of young mice and putting them in old mice made old stem cells take on the characteristics of younger stem cells. In addition, the tissues of the older mice appeared much more "youthful," according to the Harvard Stem Cell Institute researchers at the Joslin Diabetes Center.

The change in the older stem cells is driven by signals from another type of cell nearby in the bone, the researchers explained. They added that this finding improves understanding of aging of the blood-forming system and points toward blood-based treatments for age-related health problems.

The study findings are published in the Jan. 27 issue of the journal Nature.

"What's most exciting is that the changes that occur in blood stem cells during aging are reversible, through signals carried by the blood itself. This means that the blood system offers a potential therapeutic avenue for age-related stem cell dysfunction," Amy J. Wagers, an associate professor in Harvard's Department of Stem Cell and Regenerative Biology, and an investigator at the Joslin Diabetes Center, said in a news release from the center.

The study doesn't directly address diabetes-related mechanisms but "there's more and more evidence of an overlap in the regulatory pathways that are implicated in aging and in type 2 diabetes," Wagers said.

More information

The U.S. National Institutes of Health has more about stem cells.



-- Robert Preidt



SOURCE: Joslin Diabetes Center, news release, Jan. 27, 2010


'/>"/>
Copyright©2010 ScoutNews,LLC.
All rights reserved

Related medicine news :

1. Stanford researchers find culprit in aging muscles that heal poorly
2. Brain imaging reveals breakdown of normal emotional processing
3. Clarity Imaging International, Inc. Rolls Out Mobile DEXA Program
4. Oncologists are critical in managing psychiatric disorders in patients with advanced cancer
5. Fry Construction Selected for High-Profile Medical Imaging Project
6. September is Healthy Aging Month
7. The era of global aging: GSAs annual meeting to present new research on hot topics in aging
8. Elbit Medical Imaging Ltd. Announces Publication of a Prospectus in Israel
9. U.S. Health Initiative Targets Aging Hispanics
10. Ultrasonix Adds Global Medical Imaging Into Its North American Sales Force
11. Imaging Software Helps Track, Treat Injured Brains
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:3/27/2017)... ... 27, 2017 , ... Osteitis pubis may be commonplace and ... it occurs when the muscles around the pelvis become inflamed. Over time, untreated ... torso, as well as accompanying tenderness and weakness. Without proper intervention, it can ...
(Date:3/27/2017)... ... 27, 2017 , ... The Association of Healthcare and Value ... their first Northeast Regional AHVAP Meeting. For 2017, Dr. Hayes will provide the ... value analysis professionals have a ‘seat at the table’ with clinical committees when ...
(Date:3/27/2017)... ... March 27, 2017 , ... Mt. Angel ... of a months-long rebranding effort. This includes the introduction of new packaging and ... and market research, we learned that a simple, proactive approach to wellness is ...
(Date:3/27/2017)... ... 27, 2017 , ... Harris Communications, Inc., a leading provider of assistive ... to the Deaf Seniors of America Conference, April 4-7 at the Hotel Westin Galleria ... ASL friendly staff from Harris Communications and to try out the newest assistive devices ...
(Date:3/24/2017)... ... 24, 2017 , ... Vighter established its NAEMT Authorized Training ... Prehospital Trauma Life Support (PHTLS) course scholarships to four medics assigned to the ... in cooperation with the American College of Surgeons to promote critical thinking in ...
Breaking Medicine News(10 mins):
(Date:3/27/2017)... , March 27, 2017  Sanderling Ventures, portfolio ... Ethicon, a division of Johnson & Johnson. Torax manufactures ... the treatment of gastro-esophageal reflux disease (GERD). The ... (MSA) technology and the procedure is currently available ... Torax Medical was founded by Sanderling Ventures, ...
(Date:3/27/2017)... 2017 BioLineRx Ltd. (NASDAQ/TASE: BLRX), a ... that AGI-134, an immunotherapy for the treatment of multiple cancers, ... be featured at the upcoming American Association for Cancer ... to be held on April 1-5, 2017. ... An abstract ...
(Date:3/27/2017)... -- The global clinical chemistry analyzers ... 2025, according to a new study by Grand View ... anticipated to be responsible for the high urgency to ... for growth during the forecast period. In addition, growing ... susceptible to chronic diseases, is presumed to impel the ...
Breaking Medicine Technology: