Aging Brains Get Out of Sync(cent of the aged 'normal' subjects were ...),Health

Date:12/5/2007

cent of the aged 'normal' subjects were probably actually on their way to Alzheimer's disease," said Greg M. Cole, associate director of research at the Geriatric Research Education and Clinical Center of the Greater Los Angeles Veterans Administration Medical Center.

However, the study is a significant advance and the authors are correct in that they are seeing age-related changes that are not caused by Alzheimer's per se, said Cole, who is also the associate director of the UCLA Alzheimer's Disease Research Center.

"Many of the old subjects retain measures of connectivity on a par with the younger group, so these changes are not necessarily an inevitable outcome of aging," Cole added. "Whatever the cause of the declines, we'd all like to know the secrets of the group that stays in the younger performance range."

More information

For more information on Alzheimer's disease, visit the Alzheimer's Association.

SOURCES: Randy Buckner, Ph.D., professor, psychology, Harvard University, Boston; Paul Sanberg, Ph.D., D.Sc., distinguished professor of neurosurgery, and director, University of South Florida Center of Excellence for Aging and Brain Repair, Tampa; Greg M. Cole, Ph.D., associate director, research, Geriatric Research Education and Clinical Center, Greater Los Angeles Veterans Administration Medical Center, and associate director, Alzheimer's Disease Research Center; University of California, Los Angeles; Dec. 6, 2007, Neuron

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